Structural Classification of Proteins

Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like

: N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
uperfamily

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178]
multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179]
N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
uperfamily

Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (5)
Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain
Mannitol 2-dehydrogenase [81843] (1)
Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI) [48184] (2)
HCDH C-domain-like [48187] (3)
Conserved hypothetical protein MTH1747 [74762] (1)
UDP-glucose/GDP-mannose dehydrogenase dimerisation domain [48191] (2)
N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [48194] (1)
Glycerol-3-phosphate dehydrogenase [48197] (2)
Ketopantoate reductase PanE [69084] (1)
ProC C-terminal domain-like [116984] (3)
similar dimer to the class I KARI
HMD dimerization domain-like [140777] (1)
dimer similar to those of the GDP-mannose 6-dehydrogenase and class I KARI domains
TyrA dimerization domain-like [140780] (3)
new dimerisation mode with swapping of C-terminal helices