Structural Classification of Proteins
home mail help root up expand collapse

Family: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain

Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178]
    multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
  4. Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179]
    N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
    link to SUPERFAMILY database - Superfamily
  5. Family: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180]
    Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain

Protein Domains:

  1. Hydroxyisobutyrate dehydrogenase [101357]
    forms similar dimeric and tetrameric structures to the 6-phosphogluconate dehydrogenase domain and its dimer, respectively
    1. Thermus thermophilus [TaxId: 274] [101358] (8) picpic
      structural genomics
    2. Salmonella typhimurium [TaxId: 90371] [109948] (1) picpic
      SQ Q8ZLV8
    3. Pseudomonas aeruginosa [TaxId: 287] [158733] (1) picpic
      SQ Q9I5I6 163-296
  2. 6-phosphogluconate dehydrogenase (6PGD) [48181]
    duplication; contains two structural repeats
    1. Sheep (Ovis orientalis aries) [TaxId: 9940] [48182] (5) picpic
    2. Trypanosoma brucei [TaxId: 5691] [48183] (1) picpic
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk