Structural Classification of Proteins
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Family: EGF-type module

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Knottins (small inhibitors, toxins, lectins) [57015]
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
  4. Superfamily: EGF/Laminin [57196]
    link to SUPERFAMILY database - Superfamily
  5. Family: EGF-type module [57197]

Protein Domains:

  1. Factor IX (IXa) [57198]
    1. Human (Homo sapiens) [TaxId: 9606] [57199] (7)
      1. 1edm picpic
        complexed with ca
        1. chain b [44203] picpiclink
        2. chain c [44204] picpiclink
      2. 2ec9 picpicxrefxref
        automatically matched to d1pfxl1
        complexed with 24x, ca, fuc, glc
        1. region l:46-82 [146786] picpiclink
      3. 2ec9 picpicxrefxref
        automatically matched to d1pfxl2
        complexed with 24x, ca, fuc, glc
        1. region l:91-140 [146787] picpiclink
      4. 1rfn picpicxref
        complexed with ca, pbz, tbu
        1. chain b [44205] picpiclink
      5. 2zp0 picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with bgc, ca, fuc, pi0
        1. region l:46-82 [154745] picpiclink
      6. 2zp0 picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with bgc, ca, fuc, pi0
        1. region l:91-140 [154746] picpiclink
      7. 1ixa picpic
        1. chain a [44206] picpiclink
    2. Pig (Sus scrofa) [TaxId: 9823] [57200] (31)
      1. 2c4f picpicxrefxrefxref
        automatically matched to d1pfxl1
        complexed with ca, fuc, gil, glc, nag
        1. region l:46-82 [129806] picpiclink
      2. 2c4f picpicxrefxrefxref
        automatically matched to d1pfxl2
        complexed with ca, fuc, gil, glc, nag
        1. region l:91-140 [129807] picpiclink
      3. 2a2q picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with ca, cl, fuc, glc, mg, na, pbz, zn
        1. region l:46-82 [126053] picpiclink
      4. 2a2q picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with ca, cl, fuc, glc, mg, na, pbz, zn
        1. region l:91-140 [126054] picpiclink
      5. 2aer picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with ben, ca, cl, fuc, glc, mg, na, zn
        1. region l:46-82 [126641] picpiclink
      6. 2aer picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with ben, ca, cl, fuc, glc, mg, na, zn
        1. region l:91-140 [126642] picpiclink
      7. 1wtg picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with 3bp, bgc, ca, fuc
        1. region l:46-82 [121263] picpiclink
      8. 1wtg picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with 3bp, bgc, ca, fuc
        1. region l:91-140 [121264] picpiclink
      9. 2fir picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with ca, cl, fuc, glc, mg, na, zn
        1. region l:46-82 [133532] picpiclink
      10. 2fir picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with ca, cl, fuc, glc, mg, na, zn
        1. region l:91-140 [133533] picpiclink
      11. 1z6j picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with ca, mg, py3
        1. region l:46-82 [124524] picpiclink
      12. 1z6j picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with ca, mg, py3
        1. region l:91-140 [124525] picpiclink
      13. 1wun picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with bgc, ca, fuc, p5b
        1. region l:46-82 [121299] picpiclink
      14. 1wun picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with bgc, ca, fuc, p5b
        1. region l:91-140 [121300] picpiclink
      15. 1wqv picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with bgc, ca, fuc, psm
        1. region l:46-82 [121174] picpiclink
      16. 1wqv picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with bgc, ca, fuc, psm
        1. region l:91-140 [121175] picpiclink
      17. 1w0y picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with 771, bgc, ca, cac, fuc
        1. region l:46-82 [120568] picpiclink
      18. 1w0y picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with 771, bgc, ca, cac, fuc
        1. region l:91-140 [120569] picpiclink
      19. 1wss picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with 3cb, bgc, ca, fuc
        1. region l:46-82 [121239] picpiclink
      20. 1wss picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with 3cb, bgc, ca, fuc
        1. region l:91-140 [121240] picpiclink
      21. 1wv7 picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with 5pi, bgc, ca, fuc
        1. region l:46-82 [121321] picpiclink
      22. 1wv7 picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with 5pi, bgc, ca, fuc
        1. region l:91-140 [121322] picpiclink
      23. 2aei picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with 03r, ca, cac
        1. region l:46-82 [126632] picpiclink
      24. 2aei picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with 03r, ca, cac
        1. region l:91-140 [126633] picpiclink
      25. 1w2k picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with 380, bgc, ca, cac, fuc
        1. region l:46-82 [120585] picpiclink
      26. 1w2k picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with 380, bgc, ca, cac, fuc
        1. region l:91-140 [120586] picpiclink
      27. 2b8o picpicxrefxrefxrefxref
        automatically matched to d1pfxl1
        complexed with ca, cl, fuc, glc, mg, na, zn
        1. region l:46-82 [128096] picpiclink
      28. 2b8o picpicxrefxrefxrefxref
        automatically matched to d1pfxl2
        complexed with ca, cl, fuc, glc, mg, na, zn
        1. region l:91-140 [128097] picpiclink
      29. 1pfx picpicxrefxref
        complexed with doh
        1. region l:47-86 [44207] picpiclink
        2. region l:87-146 [44208] picpiclink
      30. 1x7a picpicxref
        automatically matched to d1pfxl1
        complexed with 187
        1. region l:50-86 [121782] picpiclink
      31. 1x7a picpicxref
        automatically matched to d1pfxl2
        complexed with 187
        1. region l:87-146 [121783] picpiclink
  2. Coagulation factor VIIa [57201]
    1. Human (Homo sapiens) [TaxId: 9606] [57202] (19)
      SQ P08709 108-202 ! SQ P08709 107-202
      1. 2bz6 picpicxref
        automatically matched to d1klil_
        complexed with 346, ca, so4
        1. region l:90-142 [129553] picpiclink
      2. 1w7x picpicxref
        automatically matched to d1klil_
        complexed with 413, ca, gol, so4
        1. region l:90-143 [120700] picpiclink
      3. 1kli picpicxref
        C-terminal domain
        complexed with ben, ca, gol, so4
        1. chain l [77436] picpiclink
      4. 1ygc picpicxref
        automatically matched to d1klil_
        complexed with 905, ca, so4
        1. region l:90-142 [123143] picpiclink
      5. 1jbu picpicxref
        complexed with ben, so4
        1. chain l [62857] picpiclink
      6. 1dan picpicxrefxrefxref
        complexed with ca, cac, ch2, cl, fuc, glc
        1. region l:49-86 [44209] picpiclink
        2. region l:87-142 [44210] picpiclink
      7. 1cvw picpicxref
        complexed with ans, ca
        1. chain l [44211] picpiclink
      8. 1o5d picpicxrefxref
        complexed with cr9; mutant
        1. region l:47-86 [103881] picpiclink
        2. region l:87-142 [103882] picpiclink
      9. 1fak picpicxrefxrefxrefxref
        1. region l:49-86 [44212] picpiclink
        2. region l:87-143 [44213] picpiclink
      10. 1klj picpicxref
        C-terminal domain
        complexed with ca, egl
        1. chain l [77438] picpiclink
      11. 1w8b picpicxref
        automatically matched to d1klil_
        complexed with 413, ca
        1. region l:88-143 [120717] picpiclink
      12. 1qfk picpicxref
        complexed with ca, ch2, fuc, glc, nag
        1. region l:49-86 [44214] picpiclink
        2. region l:87-144 [44215] picpiclink
      13. 1j9c picpicxrefxref
        complexed with ca, fuc, glc, nag
        1. region l:48-86 [103842] picpiclink
        2. region l:87-142 [103843] picpiclink
      14. 1dva picpicxref
        complexed with ace, ca, cac, ch2, fuc, gal, glc
        1. region l:42-86 [44216] picpiclink
        2. region l:87-142 [44217] picpiclink
        3. region m:42-86 [44218] picpiclink
        4. region m:87-142 [44219] picpiclink
      15. 1bf9 picpic
        N-terminal domain
        1. chain a [44223] picpiclink
      16. 1f7e picpic
        N-terminal domain
        1. chain a [44221] picpiclink
      17. 1ff7 picpic
        N-terminal domain
        complexed with fuc
        1. chain a [44222] picpiclink
      18. 1f7m picpic
        N-terminal domain
        1. chain a [44224] picpiclink
      19. 1ffm picpic
        N-terminal domain
        complexed with fuc
        1. chain a [44220] picpiclink
  3. E-selectin, EGF-domain [57203]
    1. Human (Homo sapiens) [TaxId: 9606] [57204] (5)
      1. 1g1t picpicxref
        complexed with 1na, ca, fuc, gal, sia
        1. region a:119-157 [65105] picpiclink
      2. 1g1s picpicxref
        complexed with fuc, gal, mpd, na, nag, nga, sia, sr
        1. region a:119-158 [65101] picpiclink
        2. region b:119-157 [65103] picpiclink
      3. 1esl picpicxref
        complexed with ca, cl
        1. region a:119-157 [44225] picpiclink
      4. 1g1q picpicxref
        complexed with ca, mpd
        1. region a:119-160 [65085] picpiclink
        2. region b:119-160 [65087] picpiclink
        3. region c:119-159 [65089] picpiclink
        4. region d:119-160 [65091] picpiclink
      5. 1g1r picpicxref
        complexed with 1na, ca, fuc, gal, mpd, sia
        1. region a:119-160 [65093] picpiclink
        2. region b:119-160 [65095] picpiclink
        3. region c:119-159 [65097] picpiclink
        4. region d:119-160 [65099] picpiclink
  4. Factor X, N-terminal module [57205]
    1. Human (Homo sapiens) [TaxId: 9606] [57206] (75)
      SQ P00742 127-178
      1. 2p3u picpicxref
        automatically matched to d1g2lb_
        complexed with 663, ca
        1. region a:87-137 [149188] picpiclink
      2. 2uwp picpicxref
        automatically matched to d1g2lb_
        complexed with 894, ca, mg
        1. region b:-2-49 [140001] picpiclink
      3. 2bok picpicxref
        automatically matched to d1g2lb_
        complexed with 784, na; mutant
        1. region l:87-138 [128917] picpiclink
      4. 2uwo picpicxref
        automatically matched to d1g2lb_
        complexed with 701
        1. region b:-2-49 [139999] picpiclink
      5. 2j4i picpicxref
        automatically matched to d1g2lb_
        complexed with ca, gsj
        1. region b:-1-49 [138004] picpiclink
      6. 2pr3 picpicxref
        automatically matched to d1g2lb_
        complexed with 237, ca
        1. region b:1-50 [149798] picpiclink
      7. 3cen picpicxref
        automatically matched to d1g2lb_
        complexed with fxa
        1. region l:87-138 [156531] picpiclink
      8. 2j2u picpicxref
        automatically matched to d1g2lb_
        complexed with gsq
        1. region b:-1-49 [137973] picpiclink
      9. 2p3t picpicxref
        automatically matched to d1g2lb_
        complexed with 993, ca, cl
        1. region a:87-138 [149186] picpiclink
      10. 2j34 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, gs6
        1. region b:-1-50 [137977] picpiclink
      11. 1z6e picpicxref
        automatically matched to d1g2lb_
        complexed with ik8
        1. region b:87-138 [124519] picpiclink
      12. 2j95 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, gsx
        1. region b:-1-50 [138148] picpiclink
      13. 2uwl picpicxref
        automatically matched to d1g2lb_
        complexed with 895
        1. region b:-2-49 [139991] picpiclink
      14. 1g2l picpicxref
        complexed with ca, t87
        1. chain b [65113] picpiclink
      15. 2j94 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, g15
        1. region b:-2-49 [138146] picpiclink
      16. 2q1j picpicxref
        automatically matched to d1g2lb_
        complexed with ca, fxi
        1. region b:0-50 [149997] picpiclink
      17. 1fjs picpicxref
        complexed with ca, cl, gol, z34
        1. chain l [44226] picpiclink
      18. 2cji picpicxref
        automatically matched to d1g2lb_
        complexed with ca, gsk
        1. region b:-1-50 [130539] picpiclink
      19. 2p93 picpicxref
        automatically matched to d1g2lb_
        complexed with me1
        1. region l:87-138 [149323] picpiclink
      20. 1lpg picpicxref
        complexed with ca, ima
        1. chain a [84666] picpiclink
      21. 1mq5 picpicxref
        complexed with ca, gol, xlc
        1. chain l [79401] picpiclink
      22. 2ei8 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, dt8
        1. region b:85-138 [146867] picpiclink
      23. 2p94 picpicxref
        automatically matched to d1g2lb_
        complexed with me4
        1. region l:87-138 [149325] picpiclink
      24. 2j38 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, gs5
        1. region b:-1-49 [137980] picpiclink
      25. 3cs7 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, lg0
        1. region l:87-138 [156957] picpiclink
      26. 1mq6 picpicxref
        complexed with ca, gol, xld
        1. chain l [79403] picpiclink
      27. 2d1j picpicxref
        automatically matched to d1g2lb_
        complexed with ca, d01
        1. region b:85-138 [131128] picpiclink
      28. 2boh picpicxref
        automatically matched to d1g2lb_
        complexed with ca, iia
        1. region a:-3-51 [128910] picpiclink
      29. 2bq7 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, iid
        1. region a:-2-49 [128963] picpiclink
      30. 2p16 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, gg2
        1. region l:87-138 [149155] picpiclink
      31. 1nfy picpicxref
        complexed with ca, rtr
        1. chain b [80474] picpiclink
      32. 2p95 picpicxref
        automatically matched to d1g2lb_
        complexed with me5
        1. region l:87-138 [149327] picpiclink
      33. 1v3x picpicxref
        complexed with ca, d76
        1. chain b [113507] picpiclink
      34. 1kye picpicxref
        complexed with ca, rup
        1. chain b [77630] picpiclink
      35. 2fzz picpicxref
        automatically matched to d1g2lb_
        complexed with 5qc
        1. region l:87-138 [134487] picpiclink
      36. 1nfu picpicxref
        complexed with ca, rrp
        1. chain b [80468] picpiclink
      37. 1nfw picpicxref
        complexed with ca, rrr
        1. chain b [80470] picpiclink
      38. 1f0r picpicxref
        complexed with 815, ca
        1. chain b [44227] picpiclink
      39. 1nfx picpicxref
        complexed with ca, rdr
        1. chain b [80472] picpiclink
      40. 1c5m picpicxref
        1. chain f [44228] picpiclink
      41. 1f0s picpicxref
        complexed with ca, pr2
        1. chain b [44229] picpiclink
      42. 1lpk picpicxref
        complexed with ca, cbb
        1. chain a [84668] picpiclink
      43. 2ei6 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, d92
        1. region b:85-138 [146863] picpiclink
      44. 1wu1 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, d91
        1. region b:85-138 [121271] picpiclink
      45. 2g00 picpicxref
        automatically matched to d1g2lb_
        complexed with 4qc
        1. region l:87-138 [134489] picpiclink
      46. 2ei7 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, d93
        1. region b:85-138 [146865] picpiclink
      47. 2h9e picpicxrefxref
        automatically matched to d1g2lb_
        complexed with act, lpd, na, po4
        1. region l:89-136 [136256] picpiclink
      48. 1ezq picpicxref
        complexed with ca, rpr
        1. chain b [44230] picpiclink
      49. 1hcg picpicxref
        1. chain b [44231] picpiclink
      50. 1iqg picpicxref
        complexed with ca, xme
        1. chain l [90675] picpiclink
      51. 2bmg picpicxref
        automatically matched to d1g2lb_
        complexed with ca, i1h
        1. region a:-2-50 [128795] picpiclink
      52. 1ksn picpicxref
        complexed with ca, fxv
        1. chain b [72925] picpiclink
      53. 1lpz picpicxref
        complexed with ca, cmb
        1. chain a [84670] picpiclink
      54. 1iqn picpicxref
        complexed with ca, xmc
        1. chain l [90689] picpiclink
      55. 2phb picpicxref
        automatically matched to d1g2lb_
        complexed with 230, ca
        1. region b:0-50 [149465] picpiclink
      56. 1lqd picpicxref
        complexed with ca, cmi
        1. chain a [84676] picpiclink
      57. 1iqm picpicxref
        complexed with ca, xmk
        1. chain l [90687] picpiclink
      58. 2bqw picpicxref
        automatically matched to d1g2lb_
        complexed with ca, iie
        1. region a:-2-49 [128971] picpiclink
      59. 1g2m picpicxref
        complexed with ca, r11
        1. chain b [65115] picpiclink
      60. 1fax picpicxref
        complexed with ca, dx9; mutant
        1. chain l [44238] picpiclink
      61. 1xkb picpicxref
        complexed with 4pp, ca, doh
        1. region a:48-86 [44232] picpiclink
        2. region a:87-138 [44233] picpiclink
        3. region b:50-86 [44234] picpiclink
        4. region b:87-139 [44235] picpiclink
      62. 1iql picpicxref
        complexed with ca, xmj
        1. chain l [90685] picpiclink
      63. 1xka picpicxref
        complexed with 4pp, ca, doh
        1. region l:49-86 [44236] picpiclink
        2. region l:87-139 [44237] picpiclink
      64. 1p0s picpicxrefxrefxref
        complexed with mg, na; mutant
        1. region l:87-138 [93874] picpiclink
      65. 1iqh picpicxref
        complexed with ca, xmf
        1. chain l [90677] picpiclink
      66. 2bq6 picpicxref
        automatically matched to d1g2lb_
        complexed with ca, iib
        1. region a:1a-49 [128961] picpiclink
      67. 1iqi picpicxref
        complexed with ca, xmg
        1. chain l [90679] picpiclink
      68. 1ioe picpicxref
        complexed with ca, xma
        1. chain l [90668] picpiclink
      69. 1iqj picpicxref
        complexed with ca, xmh
        1. chain l [90681] picpiclink
      70. 1iqk picpicxref
        complexed with ca, xmi
        1. chain l [90683] picpiclink
      71. 1iqf picpicxref
        complexed with ca, xmd
        1. chain l [90673] picpiclink
      72. 2p3f picpicxref
        automatically matched to d1g2lb_
        complexed with na
        1. region l:88-138 [149176] picpiclink
      73. 1iqe picpicxref
        complexed with ca, xmb
        1. chain l [90671] picpiclink
      74. 2gd4 picpicxrefxrefxrefxref
        automatically matched to d1g2lb_
        complexed with bma, ca, man, nag, nto; mutant
        1. region a:87-138 [135004] picpiclink
      75. 2gd4 picpicxrefxrefxrefxref
        automatically matched to d1g2lb_
        complexed with bma, ca, man, nag, nto; mutant
        1. region l:87-138 [135005] picpiclink
    2. Cow (Bos taurus) [TaxId: 9913] [57207] (5)
      1. 1kig picpicxrefxref
        1. chain l [44239] picpiclink
      2. 1ccf picpic
        complexed with hyd
        1. chain a [44241] picpiclink
      3. 1apo picpic
        complexed with oh
        1. chain a [44240] picpiclink
      4. 1whe picpicxref
        complexed with doh
        1. region a:47-86 [44242] picpiclink
      5. 1whf picpicxref
        complexed with doh
        1. region a:47-86 [44243] picpiclink
  5. Activated protein c (autoprothrombin IIa) [57208]
    1. Human (Homo sapiens) [TaxId: 9606] [57209] (1)
      1. 1aut picpicxref
        complexed with mai
        1. region l:49-96 [44244] picpiclink
        2. region l:97-146 [44245] picpiclink
  6. Prostaglandin H2 synthase-1, EGF-like module [57210]
    the rest of protein is heme-linked peroxidase, all-alpha fold
    1. Sheep (Ovis aries) [TaxId: 9940] [57211] (22)
      SQ P05979 32-584
      1. 1q4g picpicxref
        complexed with bfl, bog, gol, hem, man, nag
        1. region a:32-73 [95790] picpiclink
        2. region b:32-73 [95792] picpiclink
      2. 2ayl picpicxrefxref
        automatically matched to d1cqeb2
        complexed with bog, flp, gol, man, mnh, nag
        1. region a:32-73 [127560] picpiclink
      3. 2ayl picpicxrefxref
        automatically matched to d1cqeb2
        complexed with bog, flp, gol, man, mnh, nag
        1. region b:1032-1073 [127562] picpiclink
      4. 1eqh picpicxref
        complexed with bog, flp, hem, nag
        1. region a:33-73 [59492] picpiclink
        2. region b:33-73 [59494] picpiclink
      5. 1eqg picpicxref
        complexed with bog, hem, ibp, nag
        1. region a:33-73 [59488] picpiclink
        2. region b:33-73 [59490] picpiclink
      6. 1ht8 picpicxref
        complexed with 34c, bog, hem, nag
        1. region a:33-73 [61249] picpiclink
        2. region b:33-73 [61251] picpiclink
      7. 1ht5 picpicxref
        complexed with bog, fl2, hem, nag
        1. region a:33-73 [61245] picpiclink
        2. region b:33-73 [61247] picpiclink
      8. 1cqe picpicxref
        complexed with bog, flp, hem, nag
        1. region a:32-73 [44246] picpiclink
        2. region b:31-73 [44247] picpiclink
      9. 1diy picpicxref
        complexed with acd, bma, bog, coh, nag
        1. region a:32-73 [44249] picpiclink
      10. 2oyu picpicxref
        automatically matched to d1cqeb2
        complexed with bma, bog, hem, ims, nag
        1. region p:32-73 [149081] picpiclink
      11. 1ebv picpicxref
        complexed with hem, nag, scl
        1. region a:33-73 [44252] picpiclink
      12. 1pth picpicxrefxref
        complexed with bog, brm, hem, nag, sal
        1. region a:33-73 [44248] picpiclink
      13. 1pth picpicxrefxref
        duplicate of 1PTH 33-73
        complexed with bog, brm, hem, nag, sal
        1. region b:33-73 [118583] picpiclink
      14. 1pge picpicxref
        complexed with bog, hem, isf, nag
        1. region a:33-73 [44250] picpiclink
        2. region b:33-73 [44251] picpiclink
      15. 1igz picpicxref
        complexed with bma, bog, coh, eic, glc, nag
        1. region a:32-73 [66139] picpiclink
      16. 1fe2 picpicxref
        complexed with bma, bog, coh, lax, nag
        1. region a:32-73 [59779] picpiclink
      17. 2oye picpicxref
        automatically matched to d1cqeb2
        complexed with bma, bog, flc, hem, im8, nag, ndg
        1. region p:32-73 [149066] picpiclink
      18. 1igx picpicxref
        complexed with bma, bog, coh, epa, glc, nag
        1. region a:32-73 [66137] picpiclink
      19. 1u67 picpicxref
        complexed with acd, bma, bog, coh, nag; mutant
        1. region a:32-73 [107698] picpiclink
      20. 1prh picpicxref
        complexed with hem
        1. region a:33-73 [44253] picpiclink
        2. region b:33-73 [44254] picpiclink
      21. 1pgf picpicxref
        complexed with hem, imm, nag
        1. region a:33-73 [44257] picpiclink
        2. region b:33-73 [44258] picpiclink
      22. 1pgg picpicxref
        complexed with hem, imm, nag
        1. region a:33-73 [44255] picpiclink
        2. region b:33-73 [44256] picpiclink
    2. Mouse (Mus musculus) [TaxId: 10090] [57212] (8)
      1. 1cvu picpicxref
        complexed with acd, bog, man, nag; mutant
        1. region a:33-73 [44259] picpiclink
        2. region b:2033-2073 [44260] picpiclink
      2. 3pgh picpicxref
        complexed with flp, hem, nag
        1. region a:33-73 [44269] picpiclink
        2. region b:33-73 [44270] picpiclink
        3. region c:33-73 [44271] picpiclink
        4. region d:33-73 [44272] picpiclink
      3. 4cox picpicxref
        complexed with hem, imn, nag
        1. region a:33-73 [44265] picpiclink
        2. region b:33-73 [44266] picpiclink
        3. region c:33-73 [44267] picpiclink
        4. region d:33-73 [44268] picpiclink
      4. 6cox picpicxref
        complexed with hem, nag, s58
        1. region a:33-73 [44273] picpiclink
        2. region b:33-73 [44274] picpiclink
      5. 1cx2 picpicxref
        complexed with hem, nag, s58
        1. region a:33-73 [44261] picpiclink
        2. region b:33-73 [44262] picpiclink
        3. region c:33-73 [44263] picpiclink
        4. region d:33-73 [44264] picpiclink
      6. 1pxx picpicxref
        complexed with bog, dif, hem, nag
        1. region a:33-73 [95308] picpiclink
        2. region b:1033-1073 [95310] picpiclink
        3. region c:2033-2073 [95312] picpiclink
        4. region d:3033-3073 [95314] picpiclink
      7. 5cox picpicxref
        complexed with hem, nag
        1. region a:33-73 [44279] picpiclink
        2. region b:33-73 [44280] picpiclink
        3. region c:33-73 [44281] picpiclink
        4. region d:33-73 [44282] picpiclink
      8. 1ddx picpicxref
        complexed with bog, nag, pgx
        1. region a:33-73 [44275] picpiclink
        2. region b:1033-1073 [44276] picpiclink
        3. region c:2033-2073 [44277] picpiclink
        4. region d:3033-3073 [44278] picpiclink
  7. P-selectin, EGF-domain [57213]
    1. Human (Homo sapiens) [TaxId: 9606] [57214] (1)
      1. 1fsb picpic
        1. chain a [44283] picpiclink
  8. Epidermal growth factor, EGF [57215]
    1. Mouse (Mus musculus) [TaxId: 10090] [57216] (8)
      1. 3egf picpic
        1. chain a [44285] picpiclink
      2. 1egf picpic
        1. chain a [44290] picpiclink
      3. 1eph picpic
        1. chain a [44287] picpiclink
      4. 1a3p picpic
        complexed with aba; mutant
        1. chain a [44284] picpiclink
      5. 1epg picpic
        1. chain a [44286] picpiclink
      6. 1epj picpic
        1. chain a [44289] picpiclink
      7. 1epi picpic
        1. chain a [44288] picpiclink
      8. 1gk5 picpic
        EGF/TGFalpha chimera
        1. chain a [70209] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [69939] (4)
      1. 1nql picpicxrefxref
        complexed with EGF receptor
        complexed with aso, nag
        1. chain b [86037] picpiclink
      2. 1jl9 picpic
        1. chain a [66831] picpiclink
        2. chain b [66832] picpiclink
      3. 1ivo picpicxrefxref
        complexed with EGF receptor
        complexed with nag
        1. chain c [76853] picpiclink
        2. chain d [76854] picpiclink
      4. 1p9j picpic
        EGF/TGFalpha chimera
        1. chain a [94391] picpiclink
  9. Transforming growth factor alpha [57217]
    1. Human (Homo sapiens) [TaxId: 9606] [57218] (6)
      1. 1mox picpicxrefxref
        complexed with EGF receptor
        complexed with cd, cl, fuc, man, nag, pt
        1. chain c [91380] picpiclink
        2. chain d [91381] picpiclink
      2. 3tgf picpic
        1. chain a [44292] picpiclink
      3. 1yug picpic
        1. chain a [44293] picpiclink
      4. 2tgf picpic
        1. chain a [44291] picpiclink
      5. 4tgf picpic
        1. chain a [44294] picpiclink
      6. 1yuf picpic
        1. chain a [44295] picpiclink
  10. Epiregulin, EGF-domain [103561]
    1. Human (Homo sapiens) [TaxId: 9606] [103562] (2)
      1. 1k36 picpic
        1. chain a [90931] picpiclink
      2. 1k37 picpic
        1. chain a [90932] picpiclink
  11. Betacellulin-2 [75670]
    1. Human (Homo sapiens) [TaxId: 9606] [75671] (2)
      1. 1iox picpic
        1. chain a [71252] picpiclink
      2. 1ip0 picpic
        1. chain a [71253] picpiclink
  12. Heparin-binding epidermal growth factor, HBEGF [57219]
    extracellular domain
    1. Human (Homo sapiens) [TaxId: 9606] [57220] (1)
      1. 1xdt picpicxrefxrefxref
        1. chain r [44296] picpiclink
  13. Plasminogen activator (urokinase-type) [57221]
    1. Human (Homo sapiens) [TaxId: 9606] [57222] (12)
      1. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with po4
        1. region a:10-49 [137110] picpiclink
      2. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with po4
        1. region b:10-49 [137112] picpiclink
      3. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with po4
        1. region c:11-49 [137114] picpiclink
      4. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with po4
        1. region d:10-49 [137116] picpiclink
      5. 2fd6 picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with edo, etx, fuc, nag, pg4, pge, so4
        1. region a:11-49 [133293] picpiclink
      6. 3bt2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urka1
        complexed with nag
        1. region a:9-49 [155540] picpiclink
      7. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with bma, nag, so4; mutant
        1. region a:11-49 [137118] picpiclink
      8. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with bma, nag, so4; mutant
        1. region b:11-49 [137120] picpiclink
      9. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with bma, nag, so4; mutant
        1. region c:11-49 [137122] picpiclink
      10. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_1
        complexed with bma, nag, so4; mutant
        1. region d:11-49 [137124] picpiclink
      11. 3bt1 picpicxrefxrefxrefxrefxref
        automatically matched to d1urka1
        complexed with man, nag
        1. region a:8-49 [155534] picpiclink
      12. 1urk picpicxref
        complexed with fuc
        1. region a:6-49 [44297] picpiclink
  14. Heregulin-alpha, EGF-like domain [57223]
    1. Human (Homo sapiens) [TaxId: 9606] [57224] (4)
      1. 1hae picpic
        1. chain a [44298] picpiclink
      2. 1haf picpic
        1. chain a [44299] picpiclink
      3. 1hrf picpic
        1. chain a [44301] picpiclink
      4. 1hre picpic
        1. chain a [44300] picpiclink
  15. Thrombomodulin, different EGF-like domains [57225]
    1. Human (Homo sapiens) [TaxId: 9606] [57226] (6)
      1. 1dx5 picpicxref
        complexed with ca, fmt, na, nag; mutant
        1. region i:345-387 [44302] picpiclink
        2. region i:388-422 [44303] picpiclink
        3. region i:423-462 [44304] picpiclink
        4. region j:345-387 [44305] picpiclink
        5. region j:388-422 [44306] picpiclink
        6. region j:423-462 [44307] picpiclink
        7. region k:345-387 [44308] picpiclink
        8. region k:388-422 [44309] picpiclink
        9. region k:423-462 [44310] picpiclink
        10. region l:345-387 [44311] picpiclink
        11. region l:388-422 [44312] picpiclink
        12. region l:423-462 [44313] picpiclink
      2. 1zaq picpic
        1. chain a [44314] picpiclink
      3. 1tmr picpic
        mutant
        1. chain a [44316] picpiclink
      4. 1adx picpic
        1. chain a [44315] picpiclink
      5. 1dqb picpic
        complexed with nag
        1. region a:1-44 [44318] picpiclink
        2. region a:45-83 [44319] picpiclink
      6. 2adx picpic
        1. chain a [44317] picpiclink
  16. Fibrillin-1 [57227]
    duplication: contains 47 EFG-like domains
    1. Human (Homo sapiens) [TaxId: 9606] [57228] (8)
      1. 1uzk picpicxref
        automatically matched to d1uzja1
        complexed with ca
        1. region a:1486-1528 [119806] picpiclink
      2. 1uzk picpicxref
        automatically matched to d1uzja2
        complexed with ca
        1. region a:1605-1647 [119807] picpiclink
      3. 1uzp picpicxref
        CBEGF22 and CBEGF23
        complexed with sm
        1. region a:1486-1528 [100232] picpiclink
        2. region a:1605-1647 [100233] picpiclink
      4. 1uzj picpicxref
        CBEGF22 and CBEGF23
        complexed with ca
        1. region a:1486-1528 [100223] picpiclink
        2. region a:1605-1647 [100224] picpiclink
        3. region b:2486-2528 [100226] picpiclink
        4. region b:2605-2647 [100227] picpiclink
        5. region c:3486-3528 [100229] picpiclink
        6. region c:3605-3647 [100230] picpiclink
      5. 1uzq picpicxref
        CBEGF22 and CBEGF23
        1. region a:1486-1528 [100235] picpiclink
        2. region a:1605-1647 [100236] picpiclink
      6. 1emo picpic
        39th and 40th calcium-binding EGF-like domains
        complexed with ca
        1. region a:2124-2166 [44320] picpiclink
        2. region a:2167-2205 [44321] picpiclink
      7. 1emn picpic
        39th and 40th calcium-binding EGF-like domains
        complexed with ca
        1. region a:2124-2166 [44322] picpiclink
        2. region a:2167-2205 [44323] picpiclink
      8. 1lmj picpic
        12th and 13th calcium-binding EGF-like domains
        complexed with ca
        1. region a:3-46 [84631] picpiclink
        2. region a:47-88 [84632] picpiclink
  17. Mannose-binding protein associated serine protease 2, MASP2 [90141]
    EGF-like domain separates two CUB domains
    1. Rat (Rattus norvegicus) [TaxId: 10116] [90142] (1)
      1. 1nt0 picpicxref
        complexed with ahb, ca, edo, nag
        1. region a:120-164 [86145] picpiclink
        2. region g:120-164 [86148] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [111402] (1)
      SQ O00187 17-181
      1. 1szb picpicxref
        complexed with ca
        1. region a:124-168 [106146] picpiclink
        2. region b:124-168 [106148] picpiclink
  18. Complement C1S component [90143]
    1. Human (Homo sapiens) [TaxId: 9606] [90144] (1)
      1. 1nzi picpicxref
        complexed with ca, mg
        1. region a:118-159 [86450] picpiclink
        2. region b:118-159 [86452] picpiclink
  19. Complement protease C1R [57229]
    1. Human (Homo sapiens) [TaxId: 9606] [57230] (1)
      1. 1apq picpic
        1. chain a [44324] picpiclink
  20. Plasminogen activator (tissue-type), t-PA [57231]
    1. Human (Homo sapiens) [TaxId: 9606] [57232] (1)
      1. 1tpg picpicxref
        mutant
        1. region a:51-91 [44325] picpiclink
  21. Low density lipoprotein (LDL) receptor, different EGF domains [64539]
    1. Human (Homo sapiens) [TaxId: 9606] [64540] (7)
      SQ P01130 272-353
      1. 1ijq picpicxref
        1. region a:643-692 [62507] picpiclink
        2. region b:643-692 [62509] picpiclink
      2. 3bps picpic
        automatically matched to d1hj7a1
        complexed with ca
        1. region e:293-332 [155489] picpiclink
      3. 1i0u picpic
        complexed with ca
        1. region a:1-41 [61493] picpiclink
        2. region a:42-82 [61494] picpiclink
      4. 1hz8 picpic
        complexed with ca
        1. region a:1-41 [61432] picpiclink
        2. region a:42-82 [61433] picpiclink
      5. 1hj7 picpic
        complexed with ca
        1. region a:293-333 [61071] picpiclink
        2. region a:334-372 [61072] picpiclink
      6. 1xfe picpicxref
        complexed with ca
        1. region a:45-83 [115259] picpiclink
      7. 1n7d picpicxrefxref
        modules A, B, and C in the whole receptor structure context
        complexed with ca, keg, man, nag; mutant
        1. region a:296-332 [80237] picpiclink
        2. region a:333-376 [80238] picpiclink
        3. region a:643-693 [80239] picpiclink
  22. Neurogenic locus notch homolog protein 1, Notch1 [118243]
    1. Human (Homo sapiens) [TaxId: 9606] [118244] (4)
      SQ P46531 411-526
      1. 2vj3 picpic
        automatically matched to d1toza1
        complexed with ca, cl, na
        1. region a:411-452 [153180] picpiclink
      2. 2vj3 picpic
        automatically matched to d1toza2
        complexed with ca, cl, na
        1. region a:453-491 [153181] picpiclink
      3. 2vj3 picpic
        automatically matched to d1toza3
        complexed with ca, cl, na
        1. region a:492-526 [153182] picpiclink
      4. 1toz picpic
        mutant
        1. region a:411-452 [112605] picpiclink
        2. region a:453-491 [112606] picpiclink
        3. region a:492-526 [112607] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk