Structural Classification of Proteins
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Family: Prokaryotic type I DNA topoisomerase

domain 4 contains the catalytic tyrosine residue

Lineage:

  1. Root: scop
  2. Class: Multi-domain proteins (alpha and beta) [56572]
    Folds consisting of two or more domains belonging to different classes
  3. Fold: Prokaryotic type I DNA topoisomerase [56711]
    4 domains: (1) Toprim alpha/beta; (2&4) "winged helix"-like; (3) barrel: n=6, S=8
  4. Superfamily: Prokaryotic type I DNA topoisomerase [56712]
    duplication: the protein chain passing through the domains 2-4 makes two structural repeats
    The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV
    link to SUPERFAMILY database - Superfamily
  5. Family: Prokaryotic type I DNA topoisomerase [56713]
    domain 4 contains the catalytic tyrosine residue

Protein Domains:

  1. DNA topoisomerase I, 67K N-terminal domain [56714]
    1. Escherichia coli [TaxId: 562] [56715] (12) picpic
  2. DNA topoisomerase III [56716]
    1. Escherichia coli [TaxId: 562] [56717] (2) picpic
  3. Topoisomerase "domain" of reverse gyrase [69890]
    1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [69891] (2) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk