Superfamily: Prokaryotic type I DNA topoisomerase

duplication: the protein chain passing through the domains 2-4 makes two structural repeats
The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV
uperfamily

Lineage:

1. Root: scop
2. Class: Multi-domain proteins (alpha and beta) [56572]
   Folds consisting of two or more domains belonging to different classes
3. Fold: Prokaryotic type I DNA topoisomerase [56711]
   4 domains: (1) Toprim alpha/beta; (2&4) "winged helix"-like; (3) barrel: n=6, S=8
4. Superfamily: Prokaryotic type I DNA topoisomerase [56712]
   duplication: the protein chain passing through the domains 2-4 makes two structural repeats
   The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV
   uperfamily

Families:

1. Prokaryotic type I DNA topoisomerase [56713] (3)
   domain 4 contains the catalytic tyrosine residue
   1. DNA topoisomerase I, 67K N-terminal domain [56714]
      1. Escherichia coli [TaxId: 562] [56715] (12)
   2. DNA topoisomerase III [56716]
      1. Escherichia coli [TaxId: 562] [56717] (2)
   3. Topoisomerase "domain" of reverse gyrase [69890]
      1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [69891] (2)

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk