Fold: DNA/RNA polymerases

divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

Lineage:

1. Root: scop
2. Class: Multi-domain proteins (alpha and beta) [56572]
   Folds consisting of two or more domains belonging to different classes
3. Fold: DNA/RNA polymerases [56671]
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

Superfamilies:

1. DNA/RNA polymerases [56672] (6)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
   uperfamily
   1. DNA polymerase I [56673] (12)
   2. Lesion bypass DNA polymerase (Y-family), catalytic domain [100888] (6)
      contains a distinct 'fingers' domain possibly related to the C-terminal subdomain of hypothetical protein Ta1206 (1qw2)
   3. Reverse transcriptase [56686] (3)
   4. T7 RNA polymerase [56691] (1)
   5. RNA-dependent RNA-polymerase [56694] (11)
   6. dsRNA phage RNA-dependent RNA-polymerase [64480] (1)

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk