Structural Classification of Proteins
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Family: CBS-domain pair

Pfam 00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: CBS-domain pair [54630]
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. Superfamily: CBS-domain pair [54631]
    link to SUPERFAMILY database - Superfamily
  5. Family: CBS-domain pair [54632]
    Pfam 00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain

Protein Domains:

  1. Hypothetical protein TM0935 [102895]
    1. Thermotoga maritima [TaxId: 2336] [102896] (1) picpic
  2. Hypothetical protein MTH1622 [102897]
    1. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [102898] (1) picpic
  3. Hypothetical protein Ta0289 [102899]
    contains extra C-terminal zinc-finger domain
    1. Archaeon Thermoplasma acidophilum [TaxId: 2303] [102900] (3) picpic
  4. Type II inosine monophosphate dehydrogenase CBS domains [54633]
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
    1. Human (Homo sapiens), type I [TaxId: 9606] [89899] (1) picpic
    2. Human (Homo sapiens), type II [TaxId: 9606] [54634] (3) picpic
    3. Chinese hamster (Cricetulus griseus) [TaxId: 10029] [64260] (1) picpic
    4. Streptococcus pyogenes [TaxId: 1314] [54635] (1) picpic
  5. Hypothetical protein YkuL [117881]
    1. Bacillus subtilis [TaxId: 1423] [117882] (1) picpic
      SQ O31698 9-142
  6. Nuclear protein SNF4 [143134]
    duplication: comprises four CBS repeats
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [143135] (3) picpic
      SQ P12904 181-265
  7. Hypothetical protein TM0892, CBS tandem [143136]
    1. Thermotoga maritima [TaxId: 2336] [143137] (2) picpic
      SQ Q9WZZ4 1-60! SQ Q9WZZ4 61-121
  8. Chloride channel protein, CBS tandem [143138]
    contains additional structures between the two CBS repeats
    1. Marbled electric ray (Torpedo marmorata) [TaxId: 7788] [143139] (2) picpic
      SQ P21564 527-606! SQ P21564 691-770
  9. Hypothetical protein VC0737 [143140]
    Putative acetoin utilization protein AcuB
    1. Vibrio cholerae [TaxId: 666] [143141] (2) picpic
      SQ Q9KTZ3 21-83! SQ Q9KTZ3 93-159
  10. Hypothetical protein Rv2626c [143142]
    1. Mycobacterium tuberculosis [TaxId: 1773] [143143] (4) picpic
      SQ O06186 2-124
  11. Uncharacterized protein PH1780 [160159]
    duplication: comprises four CBS repeats
    1. Pyrococcus horikoshii [TaxId: 53953] [160160] (2) picpic
      SQ O59416 125-281! SQ O59416 126-281
  12. Uncharacterized protein ST2348 [160161]
    1. Sulfolobus tokodaii [TaxId: 111955] [160162] (2) picpic
      SQ Q96Y20 1-127
  13. Magnesium transporter MgtE [160163]
    1. Thermus thermophilus [TaxId: 274] [160164] (4) picpic
      SQ Q5SMG8 132-275
    2. Enterococcus faecalis [TaxId: 1351] [160165] (1) picpic
      SQ Q830V1 136-262
  14. Uncharacterized protein C1556.08c [160166]
    consists of 4 CBS units
    1. Schizosaccharomyces pombe [TaxId: 4896] [160167] (2) picpic
      SQ Q10343 182-334! SQ Q10343 3-181
  15. Uncharacterized protein PH0107 [160168]
    1. Pyrococcus horikoshii [TaxId: 53953] [160169] (2) picpic
      SQ O57847 4-135
  16. Uncharacterized protein SSO3205 [160170]
    duplication: comprises four CBS repeats
    1. Sulfolobus solfataricus [TaxId: 2287] [160171] (2) picpic
      SQ Q97U20 1-135! SQ Q97U20 136-276
  17. Uncharacterized protein NE2398 [160172]
    1. Nitrosomonas europaea [TaxId: 915] [160173] (4) picpic
      SQ Q82SE2 1-127
  18. Chloride channel protein 5, ClC-5 [160174]
    1. Human (Homo sapiens) [TaxId: 9606] [160175] (1) picpic
      SQ P51795 578-746
  19. 5'-AMP-activated protein kinase subunit gamma-1, AMPKg [160176]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [160177] (6) picpic
      SQ P80385 182-326! SQ P80385 23-181
  20. Uncharacterized protein PAE2072 [160178]
    2 CBS domains = 1 Bateman domain; binds two adenosine nucleotides per subunit (one per one CBS repeat)
    1. Pyrobaculum aerophilum [TaxId: 13773] [160179] (6) picpic
      SQ Q8ZVX8 2-132
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk