Structural Classification of Proteins
home mail help root up expand collapse

Protein: Type II inosine monophosphate dehydrogenase CBS domains from Human (Homo sapiens), type II [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: CBS-domain pair [54630]
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. Superfamily: CBS-domain pair [54631]
    link to SUPERFAMILY database - Superfamily
  5. Family: CBS-domain pair [54632]
    Pfam 00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain
  6. Protein: Type II inosine monophosphate dehydrogenase CBS domains [54633]
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
  7. Species: Human (Homo sapiens), type II [TaxId: 9606] [54634]

PDB Entry Domains:

  1. 1b3o picpicxref
    complexed with cpr, sae
    1. region b:112-231 [144354] picpiclink
  2. 1nf7 picpicxref
    both CBS motifs are partly disordered in both chains, A and B
    complexed with k, myd, rvp
    1. region a:112-231 [144359] picpiclink
    2. region b:112-231 [144360] picpiclink
  3. 1nfb picpicxref
    both CBS motifs are partly disordered in both chains, A and B
    complexed with cpr, nad
    1. region a:112-231 [144361] picpiclink
    2. region b:112-231 [144362] picpiclink
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk