Structural Classification of Proteins
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Family: Antibiotic resistance proteins

duplication: consists of two clear structural repeats each having this fold
subunit fold and dimeric assembly are similar to those of glyoxalase

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592]
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593]
    link to SUPERFAMILY database - Superfamily
  5. Family: Antibiotic resistance proteins [54598]
    duplication: consists of two clear structural repeats each having this fold
    subunit fold and dimeric assembly are similar to those of glyoxalase

Protein Domains:

  1. Bleomycin resistance protein, BRP [54599]
    Active as dimer
    1. Streptomyces verticillus [TaxId: 29309] [54600] (3) picpic
    2. Streptoalloteichus hindustanus [TaxId: 2017] [54601] (2) picpic
      SQ P17493
    3. Klebsiella pneumoniae [TaxId: 573] [64256] (4) picpic
      the transposon tn5-encoding bleomycin-binding protein, BlmT
  2. Mitomycin resistance protein D, MRD [75394]
    1. Streptomyces lavendulae [TaxId: 1914] [75395] (6) picpic
  3. Fosfomycin resistance protein A (FosA) [82630]
    1. Pseudomonas aeruginosa [TaxId: 287] [82631] (5) picpic
    2. Serratia marcescens [TaxId: 615] [102871] (1) picpic
      gene from transposon tn2921
  4. Fosfomycin resistance protein FosX [102872]
    1. Mesorhizobium loti [TaxId: 381] [102873] (1) picpic
  5. Hypothetical protein BC3580 [117870]
    1. Bacillus cereus [TaxId: 1396] [117871] (1) picpic
      SQ Q81AI8
  6. Hypotheical protein SP0731 [143127]
    1. Streptococcus pneumoniae [TaxId: 1313] [143128] (2) picpic
      SQ Q97RR3 1-115
  7. Uncharacterized protein Atu1953 [160145]
    1. Agrobacterium tumefaciens [TaxId: 358] [160146] (2) picpic
      SQ Q8UE11 2-115

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk