Structural Classification of Proteins
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Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

beta-alpha-beta(3); 2 layers: alpha/beta

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592]
    beta-alpha-beta(3); 2 layers: alpha/beta

Superfamilies:

  1. Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (10)
    link to SUPERFAMILY database - Superfamily
    1. Glyoxalase I (lactoylglutathione lyase) [54594] (3) picpic
      duplication: consists of two clear structural repeats each having this fold
    2. Antibiotic resistance proteins [54598] (10) picpic
      duplication: consists of two clear structural repeats each having this fold
      subunit fold and dimeric assembly are similar to those of glyoxalase
    3. Methylmalonyl-CoA epimerase [64257] (1) picpic
      Different association of repeats but a similar dimeric structure to the glyoxalase dimer
    4. Hypothetical protein YecM (EC4020) [75396] (1) picpic
      Similar subunit fold is to methylmalonyl-CoA epimerase
    5. Extradiol dioxygenases [54602] (10) picpic
      duplication: consists of 2 similar domains with 2 repeats in each
      Similar to the Methylmalonyl-CoA epimerase dimer
    6. Hypothetical protein BC1747 [110880] (1) picpic
      subunit fold and dimeric assembly are similar to those of glyoxalase
    7. 3-demethylubiquinone-9 3-methyltransferase [110883] (4) picpic
      Pfam 06983; both variants of dimeric assembly are observed in the family (domain swapping)
    8. Hypothetical protein YycE [110888] (1) picpic
      subunit fold and dimeric assembly are similar to those of glyoxalase
    9. Hypothetical protein At5g48480 [117876] (1) picpic
      subunit fold and dimeric assembly are similar to those of glyoxalase
    10. BC1024-like [143129] (1) picpic
      duplication: consists of 2 similar domains with 2 repeats in each; similar to the glyoxalase dimer
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
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