Structural Classification of Proteins
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Protein: B-Raf kinase from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Protein kinase-like (PK-like) [56111]
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily: Protein kinase-like (PK-like) [56112]
    shares functional and structural similarities with the ATP-grasp fold and PIPK
    link to SUPERFAMILY database - Superfamily
  5. Family: Protein kinases, catalytic subunit [88854]
    members organized in the groups and subfamiles specified by the comments
  6. Protein: B-Raf kinase [103290]
    OPK group; RAF subfamily; serine/threonine kinase; possible evolutionary link to tyrosine kinases
  7. Species: Human (Homo sapiens) [TaxId: 9606] [103291]

PDB Entry Domains:

  1. 1uwh picpic
    complexed with bax, cl
    1. chain a [100123] picpiclink
    2. chain b [100124] picpiclink
  2. 1uwj picpic
    complexed with bax; mutant
    1. chain a [100125] picpiclink
    2. chain b [100126] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk