Structural Classification of Proteins
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Family: Canonical RBD

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Ferredoxin-like [54861]
    alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
  4. Superfamily: RNA-binding domain, RBD [54928]
    link to SUPERFAMILY database - Superfamily
  5. Family: Canonical RBD [54929]

Protein Domains:

  1. Nuclear ribonucleoprotein A1 (RNP A1, UP1) [54930]
    duplication: contains two domains of this fold
    1. Human (Homo sapiens) [TaxId: 9606] [54931] (14) picpic
      SQ P09651 7-188
  2. Nuclear ribonucleoprotein D0 (AUF1) [75439]
    1. Human (Homo sapiens) [TaxId: 9606] [75440] (3) picpic
  3. Splicesomal U1A protein [54932]
    duplication: contains two domains of this fold
    1. Human (Homo sapiens) [TaxId: 9606] [54933] (38) picpic
      SQ P09012 1-97 ! SQ P09012 4-98 ! SQ P09012 1-98
    2. Drosophila melanogaster [TaxId: 7227] [160313] (3) picpic
      SQ P43332 1-104! SQ P43332 134-216
  4. Splicing factor U2B'' [54934]
    1. Human (Homo sapiens) [TaxId: 9606] [54935] (1) picpic
  5. Splicing factor U2AF 65 KDa subunit [54936]
    1. Human (Homo sapiens) [TaxId: 9606] [54937] (4) picpic
  6. Sex-lethal protein [54938]
    1. Drosophila melanogaster [TaxId: 7227] [54939] (4) picpic
  7. Hu antigen C (Huc) [54940]
    1. Mouse (Mus musculus) [TaxId: 10090] [54941] (3) picpic
  8. Hu antigen D (Hud) [54942]
    1. Human (Homo sapiens) [TaxId: 9606] [54943] (2) picpic
  9. Heterogeneous nuclear ribonucleoprotein d0 [54944]
    1. Human (Homo sapiens) [TaxId: 9606] [54945] (2) picpic
  10. Neural RNA-binding protein Musashi-1 [54946]
    1. Mouse (Mus musculus) [TaxId: 10090] [54947] (2) picpic
  11. Poly(A)-binding protein [54948]
    1. Human (Homo sapiens) [TaxId: 9606] [54949] (1) picpic
  12. Polypyrimidine tract-binding protein [54950]
    1. Human (Homo sapiens) [TaxId: 9606] [54951] (9) picpic
      SQ P26599 54-141, 177-284, 335-531
  13. Nucleolin [54952]
    1. Golden hamster (Mesocricetus auratus) [TaxId: 10036] [54953] (4) picpic
  14. CBP20, 20KDa nuclear cap-binding protein [64274]
    1. Human (Homo sapiens) [TaxId: 9606] [64275] (6) picpic
  15. RNA-binding protein 8 [89938]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [89939] (3) picpic
      CG8781 protein
    2. Human (Homo sapiens) [TaxId: 9606] [102978] (6) picpic
      RBM8A, Y14
  16. Lupus LA protein [89940]
    1. Human (Homo sapiens) [TaxId: 9606] [89941] (13) picpic
  17. Nuclear factor Aly [102979]
    1. Mouse (Mus musculus) [TaxId: 10090] [102980] (1) picpic
  18. Musashi-1 [102981]
    1. Mouse (Mus musculus) [TaxId: 10090] [102982] (1) picpic
  19. Cleavage stimulation factor, 64 kda subunit [102983]
    1. Human (Homo sapiens) [TaxId: 9606] [102984] (1) picpic
  20. Synaptojanin 2 [102985]
    1. Human (Homo sapiens) [TaxId: 9606] [102986] (1) picpic
  21. Heterogeneous nuclear ribonucleoprotein L-like [117951]
    1. Mouse (Mus musculus) [TaxId: 10090] [117952] (1) picpic
      SQ Q921F4 116-207
  22. Calcipressin-1 [117953]
    1. Mouse (Mus musculus) [TaxId: 10090] [117954] (1) picpic
      SQ Q9JHG6 14-103
  23. Heterogeneous nuclear ribonucleoprotein H' [117955]
    1. Human (Homo sapiens) [TaxId: 9606] [117956] (2) picpic
      SQ P55795 103-193; 280-369
  24. TAR DNA-binding protein 43, TDP-43 [117957]
    1. Human (Homo sapiens) [TaxId: 9606] [117958] (2) picpic
      SQ Q13148 193-267
  25. RNA-binding protein Raly (Autoantigen p542) [117959]
    1. Human (Homo sapiens) [TaxId: 9606] [117960] (1) picpic
      SQ Q9UKM9 1-97
  26. Heterogeneous nuclear ribonucleoproteins C1/C2 [117961]
    1. Human (Homo sapiens) [TaxId: 9606] [117962] (1) picpic
      SQ P07910 8-92
  27. Probable RNA-binding protein KIAA1579 [117963]
    1. Human (Homo sapiens) [TaxId: 9606] [117964] (1) picpic
      SQ Q9HCJ3 71-145
  28. Splicing factor, arginine/serine-rich 9 (SFRS9) [117965]
    1. Mouse (Mus musculus) [TaxId: 10090] [117966] (1) picpic
      SQ Q9D0B0 104-188
  29. Poly(A)-specific ribonuclease PARN [117967]
    1. Mouse (Mus musculus) [TaxId: 10090] [117968] (1) picpic
      SQ Q8VDG3 430-516; structure of the R3H domain (162-248) is also known (scop_sp 111031)
  30. Probable RNA-binding protein 19, Rbm19 [117969]
    1. Mouse (Mus musculus) [TaxId: 10090] [117970] (4) picpic
      SQ Q8R3C6 399-484; 581-678
  31. Putative RNA-binding protein 15B, Rbm15b [117971]
    1. Mouse (Mus musculus) [TaxId: 10090] [117972] (1) picpic
      SQ Q6PHZ5 81-164
  32. Eukaryotic translation initiation factor 4B [117973]
    1. Human (Homo sapiens) [TaxId: 9606] [117974] (1) picpic
      SQ P23588 88-178
  33. HIV Tat-specific factor 1 [143290]
    1. Human (Homo sapiens) [TaxId: 9606] [143291] (1) picpic
      SQ O43719 256-354
  34. Ataxin-2-binding protein 1 [143292]
    1. Human (Homo sapiens) [TaxId: 9606] [143293] (1) picpic
      SQ Q9NWB1 109-196
  35. E3 ubiquitin protein ligase CNOT4 [143294]
    CCR4-NOT transcription complex subunit 4
    1. Mouse (Mus musculus) [TaxId: 10090] [143295] (1) picpic
      SQ Q8BT14 101-198
  36. RNA-binding protein 41, RBM41 [143296]
    1. Human (Homo sapiens) [TaxId: 9606] [143297] (1) picpic
      SQ Q96IZ5 291-392
  37. Nucleolysin TIAR [143298]
    1. Human (Homo sapiens) [TaxId: 9606] [143299] (2) picpic
      SQ Q01085 1-90! SQ Q01085 187-282
  38. Cold-inducible RNA-binding protein [143300]
    1. Human (Homo sapiens) [TaxId: 9606] [143301] (1) picpic
      SQ Q14011 1-90
  39. Negative elongation factor E, NELF-E [143302]
    1. Human (Homo sapiens) [TaxId: 9606] [143303] (3) picpic
      SQ P18615 257-335! SQ P18615 258-341
  40. Eukaryotic translation initiation factor 3 subunit 4 [143304]
    1. Human (Homo sapiens) [TaxId: 9606] [143305] (1) picpic
      SQ O75821 231-320
  41. Matrin 3 [143306]
    1. Mouse (Mus musculus) [TaxId: 10090] [143307] (2) picpic
      SQ Q8K310 390-478! SQ Q8K310 478-576
  42. Ribonucleoprotein PTB-binding 1, Raver-1 [143308]
    1. Mouse (Mus musculus) [TaxId: 10090] [143309] (1) picpic
      SQ Q9CW46 61-135
  43. Peptidyl-prolyl cis-trans isomerase E, N-terminal domain [143310]
    1. Human (Homo sapiens) [TaxId: 9606] [143311] (1) picpic
      SQ Q9UNP9 1-89
  44. Arginine/serine-rich splicing factor 10 [143312]
    1. Human (Homo sapiens) [TaxId: 9606] [143313] (1) picpic
      SQ P62995 109-191
  45. RNA-binding protein 9 [143314]
    1. Human (Homo sapiens) [TaxId: 9606] [143315] (1) picpic
      SQ O43251 110-202
  46. Pre-mRNA branch site protein p14 [143316]
    1. Human (Homo sapiens) [TaxId: 9606] [143317] (4) picpic
      SQ Q9Y3B4 12-125
  47. Splicing factor 3B subunit 4 [143318]
    1. Human (Homo sapiens) [TaxId: 9606] [143319] (2) picpic
      SQ Q15427 102-184! SQ Q15427 4-96
  48. RNA-binding motif, single-stranded-interacting protein 2, RBMS2 [143320]
    1. Human (Homo sapiens) [TaxId: 9606] [143321] (1) picpic
      SQ Q15434 58-129
  49. RNA-binding protein UBP1 [143322]
    1. Trypanosoma cruzi [TaxId: 5693] [143323] (1) picpic
      SQ Q967R0 1-139
  50. Limkain-b1, LKAP [143324]
    KIAA0430
    1. Human (Homo sapiens) [TaxId: 9606] [143325] (1) picpic
      SQ Q9Y4F3 788-870
  51. APOBEC1 stimulating protein [143326]
    1. Human (Homo sapiens) [TaxId: 9606] [143327] (1) picpic
      SQ Q9NQ94 223-308
  52. Hypothetical protein FLJ20273 [143328]
    1. Human (Homo sapiens) [TaxId: 9606] [143329] (1) picpic
      SQ Q8NI52 150-245
  53. Nucleoporin 35 [143330]
    1. Mouse (Mus musculus) [TaxId: 10090] [143331] (4) picpic
      SQ Q8R4R6 169-249
  54. Polypyrimidine tract-binding protein 2, PTBP2 [143332]
    1. Human (Homo sapiens) [TaxId: 9606] [143333] (1) picpic
      SQ Q9UKA9 51-138
  55. Alkylation repair AlkB homolog 8, ALKBH8 [143334]
    1. Human (Homo sapiens) [TaxId: 9606] [143335] (1) picpic
      SQ Q96BT7 25-125
  56. CUG triplet repeat RNA-binding protein 1 [143336]
    1. Human (Homo sapiens) [TaxId: 9606] [143337] (1) picpic
      SQ Q92879 383-484
  57. U4/U6 snRNA-associated-splicing factor PRP24 [143338]
    contains three RBDs
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [143339] (24) picpic
      SQ P49960 116-196! SQ P49960 206-291! SQ P49960 41-115
  58. RNA-binding protein EWS [143340]
    1. Human (Homo sapiens) [TaxId: 9606] [143341] (1) picpic
      SQ Q01844 353-453
  59. Heterogeneous nuclear ribonucleoproteins A2/B1 [143342]
    1. Human (Homo sapiens) [TaxId: 9606] [143343] (1) picpic
      SQ P22626 1-103
  60. IGF-II mRNA-binding protein 2 isoform A [143344]
    1. Human (Homo sapiens) [TaxId: 9606] [143345] (1) picpic
      SQ Q9Y6M1 2-81
  61. Splicing factor, arginine/serine-rich 1, SFRS1 [143346]
    1. Human (Homo sapiens) [TaxId: 9606] [143347] (3) picpic
      SQ Q07955 1-95
    2. Mouse (Mus musculus) [TaxId: 10090] [143348] (1) picpic
      SQ Q6PDM2 112-206
  62. RNA-binding protein 12 [143349]
    3rd RBD
    1. Human (Homo sapiens) [TaxId: 9606] [143350] (2) picpic
      SQ Q9NTZ6 412-523! SQ Q9NTZ6 536-638
    2. Mouse (Mus musculus) [TaxId: 10090] [143351] (1) picpic
      SQ Q8R4X3 917-1002
  63. RNA binding protein 23 [143352]
    1. Human (Homo sapiens) [TaxId: 9606] [143353] (1) picpic
      SQ Q86U06 148-248
  64. Non-POU domain-containing octamer-binding protein, NonO [143354]
    1. Mouse (Mus musculus) [TaxId: 10090] [143355] (1) picpic
      SQ Q99K48 68-153
  65. RNA-binding motif, single-stranded-interacting protein 1, RBMS1 [143356]
    1. Human (Homo sapiens) [TaxId: 9606] [143357] (1) picpic
      SQ P29558 123-223
  66. RNA-binding protein 28 [143358]
    1. Mouse (Mus musculus) [TaxId: 10090] [143359] (1) picpic
      SQ Q8CGC6 316-413
  67. RNA-binding region containing protein 1 [143360]
    1. Human (Homo sapiens) [TaxId: 9606] [143361] (1) picpic
      SQ Q9H0Z9 1-103
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk