Structural Classification of Proteins

Superfamily: 4Fe-4S ferredoxins

: uperfamily

Lineage:

Root: scop
Class: Alpha and beta proteins (a+b) [53931]
Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold: Ferredoxin-like [54861]
alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
Superfamily: 4Fe-4S ferredoxins [54862]
uperfamily

Families:

Short-chain ferredoxins [54863] (5)
contains two 4Fe-4S clusters
1. Ferredoxin II [54864]
  1. Peptostreptococcus asaccharolyticus [TaxId: 1258] [54866] (1)
    1. 1dur
      complexed with fs4
      1. chain a [38943]
  2. Clostridium acidurici [TaxId: 1556] [54867] (3)
    1. 2fdn
      complexed with fs4
      1. chain a [38944]
    2. 1fca
      complexed with fs4
      1. chain a [38945]
    3. 1fdn
      complexed with fs4
      1. chain a [38946]
  3. Clostridium pasteurianum [TaxId: 1501] [54868] (1)
    1. 1clf
      complexed with fs4
      1. chain a [38947]
  4. Chromatium vinosum [TaxId: 1049] [54869] (1)
    1. 1blu
      complexed with fs4
      1. chain a [38948]
  5. Thauera aromatica [TaxId: 59405] [102954] (1)
    1. 1rgv
      complexed with fs4
      1. chain a [97454]
7-Fe ferredoxin [54870] (5)
has C-terminal extension to the common fold
1. Ferredoxin [54871]
  1. Azotobacter vinelandii [TaxId: 354] [54872] (32)
    1. 7fd1
      complexed with fs3, fs4
      1. chain a [38953]
    2. 6fd1
      complexed with fs3, fs4
      1. chain a [38949]
    3. 6fdr
      complexed with fs3, fs4
      1. chain a [38954]
    4. 7fdr
      complexed with fs3, fs4
      1. chain a [38955]
    5. 1pc4
      complexed with f3s, fs4; mutant
      1. chain a [94428]
    6. 1f5b
      complexed with fs3, fs4; mutant
      1. chain a [38956]
    7. 1g3o
      complexed with fs3, fs4; mutant
      1. chain a [38959]
    8. 1d3w
      complexed with fs3, fs4; mutant
      1. chain a [38957]
    9. 1f5c
      complexed with fs3, fs4, so4; mutant
      1. chain a [38958]
    10. 1pc5
      complexed with f3s, fs4; mutant
      1. chain a [94429]
    11. 1fdd
      complexed with fs3, fs4; mutant
      1. chain a [38960]
    12. 5fd1
      complexed with fs3, fs4
      1. chain a [38950]
    13. 1g6b
      complexed with fs3, fs4; mutant
      1. chain a [38963]
    14. 2fd2
      complexed with fs3, fs4; mutant
      1. chain a [38961]
    15. 1fd2
      complexed with fs3, fs4; mutant
      1. chain a [38962]
    16. 1fda
      complexed with fs3, fs4
      1. chain a [38951]
    17. 1b0t
      complexed with fs4; mutant
      1. chain a [38965]
    18. 1a6l
      complexed with fs3, fs4; mutant
      1. chain a [38966]
    19. 1fer
      complexed with f3s, f4s
      1. chain a [38952]
    20. 1fri
      complexed with fs3, fs4; mutant
      1. chain a [38964]
    21. 1frk
      complexed with fs3, fs4; mutant
      1. chain a [38967]
    22. 1ff2
      complexed with fs3, fs4; mutant
      1. chain a [38968]
    23. 1frj
      complexed with fs3, fs4; mutant
      1. chain a [38969]
    24. 1fdb
      complexed with fs3, fs4
      1. chain a [38970]
    25. 1axq
      complexed with fs3, fs4
      1. chain a [38971]
    26. 1frm
      complexed with fs3, fs4; mutant
      1. chain a [38973]
    27. 1frh
      complexed with fs3, fs4; mutant
      1. chain a [38972]
    28. 1ftc
      complexed with fs3, fs4; mutant
      1. chain a [38974]
      2. chain b [38975]
    29. 1gao
      complexed with f3s, fs4; mutant
      1. chain a [38977]
      2. chain b [38978]
      3. chain c [38979]
      4. chain d [38980]
    30. 1frl
      complexed with fs3, fs4; mutant
      1. chain a [38976]
    31. 1frx
      complexed with fs3, fs4; mutant
      1. chain a [38981]
    32. 1b0v
      1. chain a [38982]
      2. chain b [38983]
      3. chain c [38984]
      4. chain d [38985]
  2. Bacillus schlegelii [TaxId: 1484] [54873] (4)
    1. 1bc6
      complexed with fs3, fs4
      1. chain a [38986]
    2. 1bd6
      complexed with fs3, fs4
      1. chain a [38987]
    3. 1bwe
      artificial Fe8S8 ferredoxin
      complexed with fs4; mutant
      1. chain a [38988]
    4. 1bqx
      artificial Fe8S8 ferredoxin
      complexed with fs4; mutant
      1. chain a [38989]
  3. Thermus thermophilus [TaxId: 274] [69725] (1)
    1. 1h98
      complexed with fs3, fs4
      1. chain a [65743]
2. Photosystem I iron-sulfur protein PsaC [64272]
  1. Synechococcus elongatus [TaxId: 32046] [64273] (1)
    1. 1jb0
      complexed with bcr, ca, cl1, cl2, fs4, lhg, lmg, pqn
      1. chain c [62822]
  2. Synechococcus sp. pcc 7002 [TaxId: 32049] [75426] (1)
    1. 1k0t
      complexed with fs4
      1. chain a [71976]
Archaeal ferredoxins [54874] (1)
1. Ferredoxin [54875]
  the N-terminal extension to the common fold forms a part of a Zn-binding site
  1. Archaeon Sulfolobus sp. [TaxId: 2288] [54876] (1)
    1. 1xer
      complexed with fs3, mlz, zn
      1. chain a [38990]
Single 4Fe-4S cluster ferredoxin [54877] (5)
contains only one 4Fe-4S cluster
1. Ferredoxin A [54878]
  1. Thermotoga maritima [TaxId: 2336] [54879] (2)
    1. 1vjw
      complexed with fs4
      1. chain a [38991]
    2. 1rof
      complexed with fs4
      1. chain a [38992]
2. Ferredoxin I [54880]
  1. Sulfate-reducing bacteria (Desulfovibrio africanus) [TaxId: 873] [54881] (3)
    1. 1fxr
      complexed with fs4, so4
      1. chain a [38993]
      2. chain b [38994]
    2. 1dfd
      complexed with fs4
      1. chain a [38995]
    3. 1dax
      complexed with fs4
      1. chain a [38996]
  2. Desulfovibrio gigas [TaxId: 879] [54865] (2)
    1. 1fxd
      complexed with cs, f3s
      1. chain a [38941]
    2. 1f2g
      complexed with fs3
      1. chain a [38942]
3. Ferredoxin [54882]
  1. Bacillus thermoproteolyticus [TaxId: 1427] [54883] (6)
    1. 1iqz
      complexed with fs4, sul
      1. chain a [66281]
    2. 1ir0
      complexed with fs4, sul
      1. chain a [66282]
    3. 1wtf
      automatically matched to d1iqza_
      complexed with coa, f3s, so4
      1. region a:1-81 [121258]
    4. 1wtf
      automatically matched to d1iqza_
      complexed with coa, f3s, so4
      1. region b:1-81 [121259]
    5. 1wtf
      automatically matched to d1iqza_
      complexed with coa, f3s, so4
      1. region c:1-81 [121260]
    6. 1wtf
      automatically matched to d1iqza_
      complexed with coa, f3s, so4
      1. region d:1-81 [121261]
4. Fe3S4-ferredoxin PF1909 [110946]
  1. Pyrococcus furiosus [TaxId: 2261] [110947] (2)
    SQ P29603
    1. 1sj1
      complexed with f3s, nco
      1. chain a [105595]
      2. chain b [105596]
    2. 1siz
      complexed with 3co, f3s
      1. chain a [105593]
      2. chain c [105594]
Ferredoxin domains from multidomain proteins [54884] (15)
members of this "family" may be more closely related to other ferredoxins than to each other
1. Fe-only hydrogenase, second domain [54885]
  1. Clostridium pasteurianum [TaxId: 1501] [54886] (4)
    1. 3c8y
      automatically matched to d1c4aa3
      complexed with fes, gol, hcn, sf4
      1. region a:127-209 [156059]
    2. 1feh
      complexed with fs2, fsa, fsb, fsh, hc1, hc2
      1. region a:127-209 [38998]
    3. 1c4c
      1. region a:127-209 [38999]
    4. 1c4a
      1. region a:127-209 [39000]
2. Fe-only hydrogenase larger subunit, N-domain [54887]
  1. Desulfovibrio desulfuricans [TaxId: 876] [54888] (1)
    1. 1hfe
      complexed with cmo, cyn, fcy, fe2, fs4, pdt, zn
      1. region l:2-86 [39001]
      2. region m:2-86 [39002]
3. Pyruvate-ferredoxin oxidoreductase, PFOR, domain V [54889]
  1. Desulfovibrio africanus [TaxId: 873] [54890] (17)
    1. 2c42
      automatically matched to d1b0pa5
      complexed with ca, mg, pyr, sf4, tpp
      1. region a:669-785 [129794]
    2. 2c42
      automatically matched to d1b0pa5
      complexed with ca, mg, pyr, sf4, tpp
      1. region b:669-785 [129799]
    3. 2c3m
      automatically matched to d1b0pa5
      complexed with ca, cl, mg, sf4, tpp
      1. region a:669-785 [129744]
    4. 2c3m
      automatically matched to d1b0pa5
      complexed with ca, cl, mg, sf4, tpp
      1. region b:669-785 [129749]
    5. 2c3y
      automatically matched to d1b0pa5
      complexed with ca, co2, htl, mg, sf4
      1. region a:669-785 [129784]
    6. 2c3y
      automatically matched to d1b0pa5
      complexed with ca, co2, htl, mg, sf4
      1. region b:669-785 [129789]
    7. 1kek
      complexed with ca, co2, fs4, htl, mg
      1. region a:669-785 [68528]
      2. region b:669-785 [68533]
    8. 2c3p
      automatically matched to d1b0pa5
      complexed with 1tp, ca, mg, sf4
      1. region a:669-785 [129764]
    9. 2c3p
      automatically matched to d1b0pa5
      complexed with 1tp, ca, mg, sf4
      1. region b:669-785 [129769]
    10. 2uza
      automatically matched to d1b0pa5
      complexed with ca, co2, htl, mg, sf4
      1. region a:669-785 [152329]
    11. 2uza
      automatically matched to d1b0pa5
      complexed with ca, co2, htl, mg, sf4
      1. region b:669-785 [152334]
    12. 2c3u
      automatically matched to d1b0pa5
      complexed with 2tp, ca, mg, pyr, sf4
      1. region a:669-785 [129774]
    13. 2c3u
      automatically matched to d1b0pa5
      complexed with 2tp, ca, mg, pyr, sf4
      1. region b:669-785 [129779]
    14. 1b0p
      complexed with ca, fs4, mg, tpp
      1. region a:669-785 [39003]
      2. region b:669-785 [39004]
    15. 2c3o
      automatically matched to d1b0pa5
      complexed with ca, mg, pyr, sf4, tpp
      1. region a:669-785 [129754]
    16. 2c3o
      automatically matched to d1b0pa5
      complexed with ca, mg, pyr, sf4, tpp
      1. region b:669-785 [129759]
    17. 2pda
      complexed with ca, fs4, mg, pyr, tpp
      1. region a:669-785 [39005]
      2. region b:669-785 [39006]
4. Dihydropyrimidine dehydrogenase, C-terminal domain [54891]
  includes linker from domain 4
  1. Pig (Sus scrofa) [TaxId: 9823] [54892] (5)
    1. 1gte
      complexed with fad, fmn, fs4, iur
      1. region a:845-1017 [70444]
      2. region b:845-1018 [70449]
      3. region c:845-1017 [70454]
      4. region d:845-1019 [70459]
    2. 1h7w
      complexed with fad, fmn, fs4
      1. region a:845-1017 [39007]
      2. region b:845-1018 [39008]
      3. region c:845-1017 [39009]
      4. region d:845-1019 [39010]
    3. 1h7x
      complexed with fad, fmn, fs4, ndp, urf; mutant
      1. region a:845-1017 [39011]
      2. region b:845-1020 [39012]
      3. region c:845-1020 [39013]
      4. region d:845-1020 [39014]
    4. 1gth
      complexed with fad, fmn, fs4, idh, iur, ndp, ura
      1. region a:845-1020 [70487]
      2. region b:845-1020 [70492]
      3. region c:845-1020 [70497]
      4. region d:845-1020 [70502]
    5. 1gt8
      complexed with fad, fmn, fs4, ndp, uaa
      1. region a:845-1020 [70422]
      2. region b:845-1020 [70427]
      3. region c:845-1020 [70432]
      4. region d:845-1020 [70437]
5. Adenylylsulfate reductase B subunit [69726]
  includes N-terminal partly folded tail
  1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [69727] (10)
    1. 1jnr
      complexed with fad, fs4, gol
      1. chain b [66969]
      2. chain d [66973]
    2. 2fjb
      automatically matched to d1jnrb_
      complexed with amp, na, sf4, sfd
      1. region b:702-850 [133557]
    3. 2fjb
      automatically matched to d1jnrb_
      complexed with amp, na, sf4, sfd
      1. region d:2702-2850 [133558]
    4. 2fje
      automatically matched to d1jnrb_
      complexed with fad, sf4
      1. region b:702-850 [133577]
    5. 2fje
      automatically matched to d1jnrb_
      complexed with fad, sf4
      1. region d:2702-2850 [133578]
    6. 2fjd
      automatically matched to d1jnrb_
      complexed with sf4, sfd
      1. region b:702-850 [133575]
    7. 2fjd
      automatically matched to d1jnrb_
      complexed with sf4, sfd
      1. region d:2702-2850 [133576]
    8. 2fja
      automatically matched to d1jnrb_
      complexed with adx, fad, sf4
      1. region b:702-850 [133555]
    9. 2fja
      automatically matched to d1jnrb_
      complexed with adx, fad, sf4
      1. region d:2702-2850 [133556]
    10. 1jnz
      complexed with fad, fs4, so3
      1. chain b [71769]
      2. chain d [71773]
6. Formate dehydrogenase N, iron-sulfur (beta) subunit [75427]
  1. Escherichia coli [TaxId: 562] [75428] (2)
    1. 1kqf
      complexed with 6mo, cdl, cse, fs4, hem, mgd
      1. region b:2-245 [75900]
    2. 1kqg
      complexed with 6mo, cdl, cse, fs4, hem, hq, mgd
      1. region b:2-245 [75902]
7. Tungsten containing formate dehydrogenase, small subunit [82664]
  1. Desulfovibrio gigas [TaxId: 879] [82665] (1)
    1. 1h0h
      complexed with 2md, ca, cse, epe, fs4, mgd, s, w
      1. chain b [76437]
      2. chain l [76440]
8. Respiratory nitrate reductase 1 beta chain [102955]
  1. Escherichia coli [TaxId: 562] [102956] (7)
    SQ P11349
    1. 1y5i
      automatically matched to d1q16b_
      complexed with 3ph, 6mo, aga, f3s, hem, md1, sf4; mutant
      1. region b:1-509 [122641]
    2. 1q16
      complexed with 3ph, 6mo, aga, f3s, hem, md1, sf4
      1. chain b [95548]
    3. 1r27
      complexed with f3s, fs4, mgd, mo
      1. chain b [96850]
      2. chain d [96853]
    4. 1y4z
      complexed with 6mo, aga, f3s, hem, md1, pci, sf4; mutant
      1. region b:1-509 [144594]
    5. 1siw
      complexed with 3ph, f3s, gdp, hem, sf4
      1. chain b [105591]
    6. 1y5l
      automatically matched to d1q16b_
      complexed with 3ph, 6mo, f3s, hem, md1, sf4; mutant
      1. region b:1-509 [122644]
    7. 1y5n
      automatically matched to d1q16b_
      complexed with 3ph, 6mo, aga, f3s, hem, md1, pci, sf4; mutant
      1. region b:1-509 [122649]
9. Transhydroxylase beta subunit, BthL, N-terminal domain [110948]
  1. Pelobacter acidigallici [TaxId: 35816] [110949] (6)
    SQ P80564
    1. 1vlf
      complexed with 4mo, btt, ca, fs4, mgd
      1. region n:1-195 [108795]
      2. region p:1-195 [108799]
      3. region r:1-195 [108803]
      4. region t:1-195 [108807]
      5. region v:1-195 [108811]
      6. region x:1-195 [108815]
    2. 1ti6
      complexed with 4mo, btt, ca, fs4, mgd
      1. region b:1-195 [106977]
      2. region d:1-195 [106981]
      3. region f:1-195 [106985]
      4. region h:1-195 [106989]
      5. region j:1-195 [106993]
      6. region l:1-195 [106997]
    3. 1vle
      complexed with 4mo, ca, fs4, mgd, pyg
      1. region n:1-195 [108771]
      2. region p:1-195 [108775]
      3. region r:1-195 [108779]
      4. region t:1-195 [108783]
      5. region v:1-195 [108787]
      6. region x:1-195 [108791]
    4. 1ti4
      complexed with 4mo, ca, fs4, mgd, pyg
      1. region b:1-195 [106953]
      2. region d:1-195 [106957]
      3. region f:1-195 [106961]
      4. region h:1-195 [106965]
      5. region j:1-195 [106969]
      6. region l:1-195 [106973]
    5. 1vld
      complexed with 4mo, act, ca, fs4, mgd
      1. region n:1-195 [108747]
      2. region p:1-195 [108751]
      3. region r:1-195 [108755]
      4. region t:1-195 [108759]
      5. region v:1-195 [108763]
      6. region x:1-195 [108767]
    6. 1ti2
      complexed with 4mo, act, ca, fs4, mgd
      1. region b:1-195 [106929]
      2. region d:1-195 [106933]
      3. region f:1-195 [106937]
      4. region h:1-195 [106941]
      5. region j:1-195 [106945]
      6. region l:1-195 [106949]
10. NADH-quinone oxidoreductase chain 9, Nqo9 [143252]
  1. Thermus thermophilus [TaxId: 274] [143253] (4)
    SQ Q56224 26-179
    1. 2fug
      complexed with fes, fmn, sf4
      1. region 9:26-179 [134133]
    2. 2fug
      automatically matched to 2FUG 9:26-179
      complexed with fes, fmn, sf4
      1. region g:26-179 [134145]
    3. 2fug
      automatically matched to 2FUG 9:26-179
      complexed with fes, fmn, sf4
      1. region p:26-179 [134158]
    4. 2fug
      automatically matched to 2FUG 9:26-179
      complexed with fes, fmn, sf4
      1. region y:26-179 [134171]
11. NADH-quinone oxidoreductase chain 3, Nqo3, domain 2 [143254]
  1. Thermus thermophilus [TaxId: 274] [143255] (4)
    SQ Q56223 96-246
    1. 2fug
      complexed with fes, fmn, sf4
      1. region 3:96-246 [134128]
    2. 2fug
      automatically matched to 2FUG 3:96-246
      complexed with fes, fmn, sf4
      1. region c:96-246 [134141]
    3. 2fug
      automatically matched to 2FUG 3:96-246
      complexed with fes, fmn, sf4
      1. region l:96-246 [134154]
    4. 2fug
      automatically matched to 2FUG 3:96-246
      complexed with fes, fmn, sf4
      1. region u:96-246 [134167]
12. DsrB insert domain [160277]
  1. Desulfovibrio vulgaris [TaxId: 881] [160278] (2)
    SQ P45575 209-277
    1. 2v4j
      complexed with sf4, so3, srm
      1. region b:209-277 [152559]
    2. 2v4j
      automatically matched to 2V4J B:209-277
      complexed with sf4, so3, srm
      1. region e:209-277 [152566]
  2. Archaeoglobus fulgidus [TaxId: 2234] [160279] (2)
    SQ Q59110 197-261
    1. 3c7b
      complexed with sf4, so3, srm
      1. region b:197-261 [156004]
    2. 3c7b
      automatically matched to 3C7B B:197-261
      complexed with sf4, so3, srm
      1. region e:197-261 [156010]
13. DsrA insert domain [160280]
  1. Desulfovibrio vulgaris [TaxId: 881] [160281] (2)
    SQ P45574 242-322
    1. 2v4j
      complexed with sf4, so3, srm
      1. region a:242-322 [152556]
    2. 2v4j
      automatically matched to 2V4J A:242-322
      complexed with sf4, so3, srm
      1. region d:242-322 [152563]
  2. Archaeoglobus fulgidus [TaxId: 2234] [160282] (2)
    SQ Q59109 240-305
    1. 3c7b
      complexed with sf4, so3, srm
      1. region a:239-304 [156001]
    2. 3c7b
      automatically matched to 3C7B A:239-304
      complexed with sf4, so3, srm
      1. region d:239-304 [156007]
ETF-QO domain-like [143256] (1)
Pfam 05187; Electron transfer flavoprotein-ubiquinone oxidoreductase; contains single Fe4-S4 cluster
1. Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO [143257]
  1. Pig (Sus scrofa) [TaxId: 9823] [143258] (4)
    SQ P55931 506-607
    1. 2gmh
      complexed with bhg, edo, fad, na, sf4, uq5
      1. region a:483-584 [135377]
    2. 2gmh
      automatically matched to 2GMH A:483-584
      complexed with bhg, edo, fad, na, sf4, uq5
      1. region b:483-584 [135380]
    3. 2gmj
      automatically matched to 2GMH A:483-584
      complexed with fad, sf4, tbu
      1. region a:483-584 [135385]
    4. 2gmj
      automatically matched to 2GMH A:483-584
      complexed with fad, sf4, tbu
      1. region b:483-584 [135388]