Structural Classification of Proteins
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Fold: Eukaryotic type KH-domain (KH-domain type I)

beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Eukaryotic type KH-domain (KH-domain type I) [54790]
    beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

Superfamilies:

  1. Eukaryotic type KH-domain (KH-domain type I) [54791] (1)
    Prokaryotic and eukaryotic domains share a KH-motif but have different topologies
    link to SUPERFAMILY database - Superfamily
    1. Eukaryotic type KH-domain (KH-domain type I) [54792] (20)
      an RNA-binding domain
      1. Neuro-oncological ventral antigen 1, nova-1, KH3 [54793]
        1. Human (Homo sapiens) [TaxId: 9606] [54794] (1) picpic
      2. Neuro-oncological ventral antigen 2, nova-2, KH3 [54795]
        1. Human (Homo sapiens) [TaxId: 9606] [54796] (2) picpic
      3. Vigilin [54797]
        1. Human (Homo sapiens) [TaxId: 9606] [54798] (8) picpic
      4. Fragile X protein, KH1 [54799]
        1. Human (Homo sapiens) [TaxId: 9606] [54800] (1) picpic
      5. HnRNP K, KH3 [54801]
        1. Human (Homo sapiens) [TaxId: 9606] [54802] (8) picpic
      6. RNA splicing factor 1 [69699]
        1. Human (Homo sapiens) [TaxId: 9606] [69700] (1) picpic
      7. Far upstream binding element, FBP [75418]
        1. Human (Homo sapiens) [TaxId: 9606] [75419] (1) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [143219] (2) picpic
          SQ Q91WJ8 175-255! SQ Q91WJ8 89-168
      8. Hypothetical protein APE0754 [110927]
        duplication: tandem repeat of two KH-1 domains
        1. Aeropyrum pernix [TaxId: 56636] [110928] (1) picpic
          SQ Q9YE16
      9. Tudor and KH domain containing protein, Tdrkh [117912]
        1. Mouse (Mus musculus) [TaxId: 10090] [117913] (1) picpic
          SQ Q80VL1 118-208
      10. Poly(RC)-binding protein 2 [143220]
        contains three KH domains
        1. Human (Homo sapiens) [TaxId: 9606] [143221] (12) picpic
          SQ Q15366 11-81
      11. Fragile X mental retardation syndrome related protein 1, FXR1 [143222]
        1. Human (Homo sapiens) [TaxId: 9606] [143223] (1) picpic
          SQ P51114 212-289
      12. Poly(RC)-binding protein 1 [143224]
        1. Human (Homo sapiens) [TaxId: 9606] [143225] (1) picpic
          SQ Q15365 279-348
      13. Quaking protein A (Xqua) [143226]
        1. African clawed frog (Xenopus laevis) [TaxId: 8355] [143227] (1) picpic
          SQ Q32NN2 82-215
      14. Ribosomal RNA-processing protein 4, RRP4 [160227]
        1. Human (Homo sapiens) [TaxId: 9606] [160228] (1) picpic
          SQ Q13868 168-293
      15. Exosome complex RNA-binding protein 1, ECR1 [160229]
        1. Archaeoglobus fulgidus [TaxId: 2234] [160230] (3) picpic
          SQ O29758 136-219
        2. Aeropyrum pernix [TaxId: 56636] [160231] (1) picpic
          SQ Q9YC02 148-234
        3. Sulfolobus solfataricus [TaxId: 2287] [160232] (2) picpic
          SQ Q9UXC4 153-221
      16. Ribosomal RNA-processing protein 40, RRP40 [160233]
        1. Saccharomyces cerevisiae [TaxId: 4932] [160234] (1) picpic
          SQ Q08285 152-236
        2. Human (Homo sapiens) [TaxId: 9606] [160235] (1) picpic
          SQ Q9NQT5 196-275
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk