Structural Classification of Proteins
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Fold: Eukaryotic type KH-domain (KH-domain type I)

beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Eukaryotic type KH-domain (KH-domain type I) [54790]
    beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta

Superfamilies:

  1. Eukaryotic type KH-domain (KH-domain type I) [54791] (1)
    Prokaryotic and eukaryotic domains share a KH-motif but have different topologies
    link to SUPERFAMILY database - Superfamily
    1. Eukaryotic type KH-domain (KH-domain type I) [54792] (20)
      an RNA-binding domain
      1. Neuro-oncological ventral antigen 1, nova-1, KH3 [54793]
        1. Human (Homo sapiens) [TaxId: 9606] [54794] (1)
          1. 1dt4 picpic
            1. chain a [38799] picpiclink
      2. Neuro-oncological ventral antigen 2, nova-2, KH3 [54795]
        1. Human (Homo sapiens) [TaxId: 9606] [54796] (2)
          1. 1dtj picpic
            1. chain a [38800] picpiclink
            2. chain b [38801] picpiclink
            3. chain c [38802] picpiclink
            4. chain d [38803] picpiclink
          2. 1ec6 picpic
            1. chain a [38804] picpiclink
            2. chain b [38805] picpiclink
      3. Vigilin [54797]
        1. Human (Homo sapiens) [TaxId: 9606] [54798] (8)
          1. 2ctf picpic
            1. region a:7-96 [130795] picpiclink
          2. 2ctl picpic
            1. region a:8-91 [130798] picpiclink
          3. 2ctk picpic
            1. region a:8-98 [130797] picpiclink
          4. 2ctm picpic
            1. region a:8-88 [130799] picpiclink
          5. 2cte picpic
            1. region a:8-88 [130794] picpiclink
          6. 2ctj picpic
            1. region a:8-89 [130796] picpiclink
          7. 1vig picpic
            1. chain a [38806] picpiclink
          8. 1vih picpic
            1. chain a [38807] picpiclink
      4. Fragile X protein, KH1 [54799]
        1. Human (Homo sapiens) [TaxId: 9606] [54800] (1)
          1. 2fmr picpic
            1. chain a [38808] picpiclink
      5. HnRNP K, KH3 [54801]
        1. Human (Homo sapiens) [TaxId: 9606] [54802] (8)
          1. 1zzk picpic
            automatically matched to d1j5ka_
            1. region a:11-85 [125909] picpiclink
          2. 1zzi picpic
            automatically matched to d1j5ka_
            1. region a:11-85 [125904] picpiclink
          3. 1zzi picpic
            automatically matched to d1j5ka_
            1. region b:11-85 [125905] picpiclink
          4. 1zzj picpic
            automatically matched to d1j5ka_
            1. region a:11-83 [125906] picpiclink
          5. 1zzj picpic
            automatically matched to d1j5ka_
            1. region b:11-81 [125907] picpiclink
          6. 1zzj picpic
            automatically matched to d1j5ka_
            1. region c:11-81 [125908] picpiclink
          7. 1j5k picpic
            1. chain a [71565] picpiclink
          8. 1khm picpic
            1. chain a [38809] picpiclink
      6. RNA splicing factor 1 [69699]
        1. Human (Homo sapiens) [TaxId: 9606] [69700] (1)
          1. 1k1g picpic
            1. chain a [68015] picpiclink
      7. Far upstream binding element, FBP [75418]
        1. Human (Homo sapiens) [TaxId: 9606] [75419] (1)
          1. 1j4w picpic
            mutant
            1. region a:1-74 [71529] picpiclink
            2. region a:104-174 [71530] picpiclink
        2. Mouse (Mus musculus) [TaxId: 10090] [143219] (2)
          SQ Q91WJ8 175-255! SQ Q91WJ8 89-168
          1. 1x4m picpic
            2nd KH domain
            1. region a:8-88 [121695] picpiclink
          2. 1x4n picpic
            1st KH domain
            1. region a:8-86 [121696] picpiclink
      8. Hypothetical protein APE0754 [110927]
        duplication: tandem repeat of two KH-1 domains
        1. Aeropyrum pernix [TaxId: 56636] [110928] (1)
          SQ Q9YE16
          1. 1tua picpic
            1. region a:1-84 [107321] picpiclink
            2. region a:85-188 [107322] picpiclink
      9. Tudor and KH domain containing protein, Tdrkh [117912]
        1. Mouse (Mus musculus) [TaxId: 10090] [117913] (1)
          SQ Q80VL1 118-208
          1. 1we8 picpic
            Structural genomics target; 2nd KH domain
            1. chain a [114548] picpiclink
      10. Poly(RC)-binding protein 2 [143220]
        contains three KH domains
        1. Human (Homo sapiens) [TaxId: 9606] [143221] (12)
          SQ Q15366 11-81
          1. 2axy picpic
            1st KH domain
            1. region a:11-81 [127532] picpiclink
          2. 2axy picpic
            automatically matched to 2AXY A:11-81
            1. region b:12-81 [127533] picpiclink
          3. 2axy picpic
            automatically matched to 2AXY A:11-81
            1. region c:11-81 [127534] picpiclink
          4. 2axy picpic
            automatically matched to 2AXY A:11-81
            1. region d:12-81 [127535] picpiclink
          5. 2pqu picpic
            automatically matched to 2AXY A:11-81
            1. region a:11-81 [139744] picpiclink
          6. 2pqu picpic
            automatically matched to 2AXY A:11-81
            1. region b:12-81 [139745] picpiclink
          7. 2pqu picpic
            automatically matched to 2AXY A:11-81
            1. region c:12-81 [139746] picpiclink
          8. 2pqu picpic
            automatically matched to 2AXY A:11-81
            1. region d:12-81 [139747] picpiclink
          9. 2py9 picpic
            automatically matched to 2AXY A:11-81
            1. region a:11-81 [139776] picpiclink
          10. 2py9 picpic
            automatically matched to 2AXY A:11-81
            1. region b:13-81 [139777] picpiclink
          11. 2py9 picpic
            automatically matched to 2AXY A:11-81
            1. region c:13-81 [139778] picpiclink
          12. 2py9 picpic
            automatically matched to 2AXY A:11-81
            1. region d:13-81 [139779] picpiclink
      11. Fragile X mental retardation syndrome related protein 1, FXR1 [143222]
        1. Human (Homo sapiens) [TaxId: 9606] [143223] (1)
          SQ P51114 212-289
          1. 2cpq picpic
            1st KH domain
            1. region a:212-289 [130704] picpiclink
      12. Poly(RC)-binding protein 1 [143224]
        1. Human (Homo sapiens) [TaxId: 9606] [143225] (1)
          SQ Q15365 279-348
          1. 1wvn picpic
            3rd KH domain
            1. region a:5-74 [121345] picpiclink
      13. Quaking protein A (Xqua) [143226]
        1. African clawed frog (Xenopus laevis) [TaxId: 8355] [143227] (1)
          SQ Q32NN2 82-215
          1. 2bl5 picpic
            1. region a:1-134 [128728] picpiclink
      14. Ribosomal RNA-processing protein 4, RRP4 [160227]
        1. Human (Homo sapiens) [TaxId: 9606] [160228] (1)
          SQ Q13868 168-293
          1. 2nn6 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
            mutant
            1. region h:168-293 [148312] picpiclink
      15. Exosome complex RNA-binding protein 1, ECR1 [160229]
        1. Archaeoglobus fulgidus [TaxId: 2234] [160230] (3)
          SQ O29758 136-219
          1. 2ba0 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
            1. region a:136-219 [146098] picpiclink
          2. 2ba0 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
            automatically matched to 2BA0 A:136-219
            1. region b:136-219 [146101] picpiclink
          3. 2ba0 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
            automatically matched to 2BA0 A:136-219
            1. region c:136-219 [146104] picpiclink
        2. Aeropyrum pernix [TaxId: 56636] [160231] (1)
          SQ Q9YC02 148-234
          1. 2z0s picpicxref
            1. region a:148-234 [153917] picpiclink
        3. Sulfolobus solfataricus [TaxId: 2287] [160232] (2)
          SQ Q9UXC4 153-221
          1. 2je6 picpicxrefxrefxrefxrefxrefxref
            complexed with 1pe, cl, peg; mutant
            1. region i:153-221 [147997] picpiclink
          2. 2jea picpicxrefxrefxrefxrefxrefxref
            automatically matched to 2JE6 I:153-221
            complexed with 1pe; mutant
            1. region i:153-221 [148014] picpiclink
      16. Ribosomal RNA-processing protein 40, RRP40 [160233]
        1. Saccharomyces cerevisiae [TaxId: 4932] [160234] (1)
          SQ Q08285 152-236
          1. 2ja9 picpicxref
            1. region a:152-236 [147951] picpiclink
        2. Human (Homo sapiens) [TaxId: 9606] [160235] (1)
          SQ Q9NQT5 196-275
          1. 2nn6 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
            mutant
            1. region g:195-274 [148309] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk