Structural Classification of Proteins

Fold: Nucleotide-diphospho-sugar transferases

: 3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: Nucleotide-diphospho-sugar transferases [53447]
3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

Superfamilies:

Nucleotide-diphospho-sugar transferases [53448] (19)
uperfamily
1. Spore coat polysaccharide biosynthesis protein SpsA [53449] (1)
  1. Spore coat polysaccharide biosynthesis protein SpsA [53450]
    1. Bacillus subtilis [TaxId: 1423] [53451] (5)
2. beta 1,4 galactosyltransferase (b4GalT1) [53452] (1)
  1. beta 1,4 galactosyltransferase (b4GalT1) [53453]
    1. Cow (Bos taurus) [TaxId: 9913] [53454] (22)
      SQ P08037 131-402
3. Galactosyltransferase LgtC [53458] (1)
  1. Galactosyltransferase LgtC [53459]
    1. Neisseria meningitidis [TaxId: 487] [53460] (3)
      SQ Q93EK7
4. Glycogenin [75273] (1)
  1. Glycogenin [75274]
    1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [75275] (10)
5. alpha-1,3-galactosyltransferase-like [64131] (3)
  1. alpha-1,3-galactosyltransferase catalytic domain [64132]
    1. Cow (Bos taurus) [TaxId: 9913] [64133] (23)
      SQ P14769
  2. Glycosyltransferase A catalytic domain [75276]
    involved in blood group antigen biosynthesis
    1. Human (Homo sapiens) [TaxId: 9606] [75277] (19)
      SQ P16442 64-345
  3. Glycosyltransferase B [75278]
    involved in blood group antigen biosynthesis
    1. Human (Homo sapiens) [TaxId: 9606] [75279] (18)
6. UDP-glucose pyrophosphorylase [53461] (6)
  1. N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain [53462]
    1. Escherichia coli [TaxId: 562] [53463] (9)
    2. Streptococcus pneumoniae [TaxId: 1313] [64134] (5)
  2. UDP-N-acetylglucosamine pyrophosphorylase [75280]
    1. Human (Homo sapiens), AGX1 [TaxId: 9606] [75281] (2)
    2. Human (Homo sapiens), AGX2 [TaxId: 9606] [82490] (2)
    3. Mouse (Mus musculus), AGX2 [TaxId: 10090] [117698] (1)
      SQ Q91YN5
  3. UDP-glucose pyrophosphorylase 2 (UDPGP 2) [142686]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [142687] (8)
      SQ Q9M9P3 6-383
7. glucose-1-phosphate thymidylyltransferase [53464] (6)
  1. RmlA (RfbA) [53465]
    1. Pseudomonas aeruginosa [TaxId: 287] [53466] (7)
    2. Salmonella enterica [TaxId: 28901] [64135] (5)
    3. Escherichia coli [TaxId: 562] [69568] (3)
    4. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [89759] (1)
  2. RffH [82491]
    1. Escherichia coli [TaxId: 562] [82492] (1)
  3. Glucose-1-phosphate adenylyltransferase small subunit, catalytic domain [142688]
    1. Potato (Solanum tuberosum) [TaxId: 4113] [142689] (12)
      SQ P23509 80-386
8. 1,3-glucuronyltransferase [53467] (2)
  1. 1,3-Glucuronyltransferase I (glcAT-I) [53468]
    1. Human (Homo sapiens) [TaxId: 9606] [53469] (4)
  2. Beta-1,3-glucuronyltransferase 1, GlcAT-P [110687]
    1. Human (Homo sapiens) [TaxId: 9606] [110688] (3)
      SQ Q9P2W7
9. N-acetylglucosaminyltransferase I [64136] (1)
  1. N-acetylglucosaminyltransferase I [64137]
    1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [64138] (7)
10. Exostosin [89760] (1)
  1. Alpha-1,4-N-acetylhexosaminyltransferase (Alpha-GalNAcT EXTL2) [89761]
    1. Mouse (Mus musculus) [TaxId: 10090] [89762] (4)
11. Molybdenum cofactor biosynthesis protein MobA [53470] (1)
  1. Molybdenum cofactor biosynthesis protein MobA [53471]
    1. Escherichia coli [TaxId: 562] [53472] (8)
12. Cytidylytransferase [68901] (12)
  1. 4-diphosphocytidyl-2C-methyl-D-erythritol (CDP-me) synthase (IspD, YgbP) [64140]
    1. Escherichia coli [TaxId: 562] [64141] (6)
    2. Neisseria gonorrhoeae [TaxId: 485] [102605] (2)
    3. Thermotoga maritima [TaxId: 2336] [117699] (1)
      SQ Q9X1B3
    4. Thale cress (Arabidopsis thaliana), chloroplast [TaxId: 3702] [142690] (1)
      SQ P69834 75-300
  2. CMP:2-keto-3-deoxy-manno-octonic acid (CMP-KDO)synthetase [64143]
    1. Escherichia coli, KpsU [TaxId: 562] [64144] (8)
      capsule-specific enzyme
    2. Escherichia coli, KdsB [TaxId: 562] [102606] (1)
    3. Haemophilus influenzae [TaxId: 727] [102607] (2)
  3. CTP:phosphocholine cytidylytransferase LicC [69569]
    1. Streptococcus pneumoniae [TaxId: 1313] [69570] (2)
  4. CMP acylneuraminate synthetase [53456]
    a sialic acid activating synthetase
    1. Neisseria meningitidis [TaxId: 487] [53457] (2)
    2. Mouse (Mus musculus) [TaxId: 10090] [102608] (1)
  5. Glucose-1-phosphate cytidylyltransferase RfbF [110689]
    1. Salmonella typhimurium [TaxId: 90371] [110690] (2)
      SQ P26396 2-257
  6. IspD/IspF bifunctional enzyme, CDP-me synthase domain [117700]
    1. Campylobacter jejuni [TaxId: 197] [117701] (2)
      SQ Q9PM68
13. Glycolipid 2-alpha-mannosyltransferase [102609] (1)
  1. Glycolipid 2-alpha-mannosyltransferase [102610]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [102611] (3)
14. Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain [117702] (1)
  1. Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain [117703]
    1. Mouse (Mus musculus) [TaxId: 10090] [117704] (1)
      SQ O08912
15. MGS-like [142691] (1)
  contains extra C-terminal all-alpha subdomain: 5 helices, orthogonal array
  1. Mannosylglycerate synthase, MGS [142692]
    1. Rhodothermus marinus [TaxId: 29549] [142693] (28)
      SQ Q9RFR0 2-382
16. TTHA0179-like [159717] (1)
  1. Uncharacterized protein TTHA0179 [159718]
    1. Thermus thermophilus [TaxId: 274] [159719] (1)
      SQ Q5SLW4 1-231
17. mannose-1-phosphate guanylyl transferase [159720] (1)
  1. Putative mannose-1-phosphate guanylyl transferase (GDP)/mannose-6-phosphate isomerase TTHA1750 [159721]
    1. Thermus thermophilus [TaxId: 274] [159722] (1)
      SQ Q5SHI0 1-268
18. MM2497-like [159723] (1)
  Pfam 01983; DUF121
  1. Hypothetical protein MM2497 [159724]
    1. Methanosarcina mazei [TaxId: 2209] [159725] (2)
      SQ Q8PU52 1-208
19. Glycosylating toxin catalytic domain-like [159726] (3)
  contains Glycosyltransferase sugar-binding region containing DXD motif, Pfam 04488
  1. Cytotoxin L [159727]
    1. Clostridium sordellii [TaxId: 1505] [159728] (9)
      SQ Q46342 1-542
  2. Alpha-toxin [159729]
    1. Clostridium novyi [TaxId: 1542] [159730] (1)
      SQ Q46149 2-541
  3. Toxin B [159731]
    1. Clostridium difficile [TaxId: 1496] [159732] (2)
      SQ P18177 1-542