Structural Classification of Proteins
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Protein: HCV helicase domain from Human hepatitis C virus (HCV), different isolates [TaxId: 11103]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: P-loop containing nucleoside triphosphate hydrolases [52539]
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily: P-loop containing nucleoside triphosphate hydrolases [52540]
    division into families based on beta-sheet topologies
    link to SUPERFAMILY database - Superfamily
  5. Family: RNA helicase [52724]
    duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension
  6. Protein: HCV helicase domain [52725]
  7. Species: Human hepatitis C virus (HCV), different isolates [TaxId: 11103] [52726]

PDB Entry Domains:

  1. 1a1v picpic
    protein/DNA complex; complexed with so4; mutant
    1. region a:190-325 [32467] picpiclink
    2. region a:326-624 [32468] picpiclink
  2. 1hei picpic
    complexed with ca
    1. region a:187-325 [32463] picpiclink
    2. region a:326-629 [32464] picpiclink
    3. region b:188-325 [32465] picpiclink
    4. region b:326-628 [32466] picpiclink
  3. 8ohm picpic
    1. region a:190-325 [32469] picpiclink
    2. region a:326-624 [32470] picpiclink
  4. 1cu1 picpicxref
    complexed with po4, zn
    1. region a:187-325 [32471] picpiclink
    2. region a:326-631 [32472] picpiclink
    3. region b:1187-1325 [32473] picpiclink
    4. region b:1326-1631 [32474] picpiclink
  5. 1onb picpic
    an engineered arginine-rich subdomain 2
    1. chain a [87137] picpiclink
  6. 1jr6 picpic
    an engineered arginine-rich subdomain 2
    1. chain a [71821] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk