Structural Classification of Proteins
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Protein: NS3 protease from Human hepatitis C virus (HCV), different isolates [TaxId: 11103]

SQ P27958 1027-1206,1678-1669
SQ P26662 1029-1202,1677-1689
SQ O36579 1054-1207

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Trypsin-like serine proteases [50493]
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. Superfamily: Trypsin-like serine proteases [50494]
    link to SUPERFAMILY database - Superfamily
  5. Family: Viral proteases [50596]
    beta sheet in the first domain is opened rather than forms a barrel
  6. Protein: NS3 protease [50600]
  7. Species: Human hepatitis C virus (HCV), different isolates [TaxId: 11103] [50601]
    SQ P27958 1027-1206,1678-1669
    SQ P26662 1029-1202,1677-1689
    SQ O36579 1054-1207

PDB Entry Domains:

  1. 1dy9 picpic
    complexed with boc, fki, zn
    1. chain a,c [26400] picpiclink
    2. chain b,d [26401] picpiclink
  2. 1w3c picpic
    complexed with dn1, dn2; mutant
    1. chain a,c [114138] picpiclink
    2. chain b,d [114139] picpiclink
  3. 1a1r picpic
    complexed with zn; mutant
    1. chain a,c [26406] picpiclink
    2. chain b,d [26407] picpiclink
  4. 1n1l picpic
    complexed with trl, zn; mutant
    1. chain a,c [91544] picpiclink
    2. chain b,d [91545] picpiclink
  5. 1dxp picpic
    complexed with gol, zn
    1. chain a,c [26404] picpiclink
    2. chain b,d [26405] picpiclink
  6. 1jxp picpic
    complexed with zn
    1. chain a,c [26402] picpiclink
    2. chain b,d [26403] picpiclink
  7. 1rtl picpic
    complexed with cpx, zn
    1. chain a,c [111934] picpiclink
    2. chain b,d [144371] picpiclink
  8. 1cu1 picpicxref
    complexed with po4, zn
    1. region a:705-720,a:3-186 [26408] picpiclink
    2. region b:1705-1720,b:1003-1186 [26409] picpiclink
  9. 1dy8 picpic
    complexed with cbz, fki
    1. chain a,c [26410] picpiclink
    2. chain b,d [26411] picpiclink
  10. 1ns3 picpic
    complexed with zn; mutant
    1. chain a,c [26412] picpiclink
    2. chain b,d [26413] picpiclink
  11. 1a1q picpic
    complexed with zn
    1. chain a [26414] picpiclink
    2. chain b [26415] picpiclink
    3. chain c [26416] picpiclink
  12. 1rgq picpic
    complexed with akp, zn
    1. chain a,d [111803] picpiclink
    2. chain b,c [111804] picpiclink
  13. 1dxw picpic
    complexed with abk, zn; mutant
    1. chain a [26417] picpiclink
  14. 1bt7 picpic
    complexed with zn; mutant
    1. chain a [26418] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk