Structural Classification of Proteins
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Protein: Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from Human (Homo sapiens) [TaxId: 9606]

SQ P13569 389-671

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: P-loop containing nucleoside triphosphate hydrolases [52539]
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily: P-loop containing nucleoside triphosphate hydrolases [52540]
    division into families based on beta-sheet topologies
    link to SUPERFAMILY database - Superfamily
  5. Family: ABC transporter ATPase domain-like [52686]
    there are two additional subdomains inserted into the central core that has a RecA-like topology
  6. Protein: Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [117543]
    SQ P13569 389-671

PDB Entry Domains:

  1. 1xmi picpic
    complexed with atp, mg; mutant
    1. chain a [115489] picpiclink
    2. chain b [115490] picpiclink
    3. chain c [115491] picpiclink
    4. chain d [115492] picpiclink
    5. chain e [115493] picpiclink
  2. 1xmj picpic
    complexed with atp, mg; mutant
    1. chain a [115494] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk