Structural Classification of Proteins
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Protein: Glucosylceramidase, catalytic domain from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: TIM beta/alpha-barrel [51350]
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily: (Trans)glycosidases [51445]
    link to SUPERFAMILY database - Superfamily
  5. Family: beta-glycanases [51487]
    consist of a number of sequence families
  6. Protein: Glucosylceramidase, catalytic domain [89473]
    acid-beta-glucosidase; glycosyl hydrolase family 30; contains additional beta-domain similar to one found in alpha amylases
  7. Species: Human (Homo sapiens) [TaxId: 9606] [89474]

PDB Entry Domains:

  1. 2nt0 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
    1. region a:78-431 [138562] picpiclink
  2. 2nt0 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
    1. region b:78-431 [138564] picpiclink
  3. 2nt0 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
    1. region c:78-431 [138566] picpiclink
  4. 2nt0 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
    1. region d:78-431 [138568] picpiclink
  5. 2v3d picpicxrefxref
    automatically matched to d1ogsa2
    complexed with bma, fuc, nag, nbv, so4
    1. region a:78-431 [152446] picpiclink
  6. 2v3d picpicxrefxref
    automatically matched to d1ogsa2
    complexed with bma, fuc, nag, nbv, so4
    1. region b:78-431 [152448] picpiclink
  7. 2v3f picpicxrefxref
    automatically matched to d1ogsa2
    complexed with btb, fuc, man, nag, so4
    1. region a:78-431 [152454] picpiclink
  8. 2v3f picpicxrefxref
    automatically matched to d1ogsa2
    complexed with btb, fuc, man, nag, so4
    1. region b:78-431 [152456] picpiclink
  9. 2v3e picpicxrefxref
    automatically matched to d1ogsa2
    complexed with bma, fuc, nag, nnd, po4
    1. region a:78-431 [152450] picpiclink
  10. 2v3e picpicxrefxref
    automatically matched to d1ogsa2
    complexed with bma, fuc, nag, nnd, po4
    1. region b:78-431 [152452] picpiclink
  11. 1ogs picpicxref
    complexed with nag, ndg, so4
    1. region a:78-431 [86998] picpiclink
    2. region b:78-431 [87000] picpiclink
  12. 2vt0 picpicxrefxref
    automatically matched to d1ogsa2
    complexed with cbu, fuc, man, nag, so4
    1. region a:78-431 [153534] picpiclink
  13. 2vt0 picpicxrefxref
    automatically matched to d1ogsa2
    complexed with cbu, fuc, man, nag, so4
    1. region b:78-431 [153536] picpiclink
  14. 2nsx picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
    1. region a:78-431 [138553] picpiclink
  15. 2nsx picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
    1. region b:78-431 [138555] picpiclink
  16. 2nsx picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
    1. region c:78-431 [138557] picpiclink
  17. 2nsx picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
    1. region d:78-431 [138559] picpiclink
  18. 2nt1 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with nag, po4
    1. region a:78-431 [138570] picpiclink
  19. 2nt1 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with nag, po4
    1. region b:78-431 [138572] picpiclink
  20. 2nt1 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with nag, po4
    1. region c:78-431 [138574] picpiclink
  21. 2nt1 picpicxrefxrefxrefxref
    automatically matched to d1ogsa2
    complexed with nag, po4
    1. region d:78-431 [138576] picpiclink
  22. 2f61 picpicxrefxref
    automatically matched to d1ogsa2
    complexed with nag, ndg, so4
    1. region a:78-431 [133018] picpiclink
  23. 2f61 picpicxrefxref
    automatically matched to d1ogsa2
    complexed with nag, ndg, so4
    1. region b:78-431 [133020] picpiclink
  24. 1y7v picpicxrefxref
    automatically matched to d1ogsa2
    complexed with ins, nag, so4; mutant
    1. region a:78-431 [122726] picpiclink
  25. 1y7v picpicxrefxref
    automatically matched to d1ogsa2
    complexed with ins, nag, so4; mutant
    1. region b:78-431 [122728] picpiclink
  26. 2j25 picpicxrefxref
    automatically matched to d1ogsa2
    complexed with bma, man, nag, so4
    1. region a:78-431 [137956] picpiclink
  27. 2j25 picpicxrefxref
    automatically matched to d1ogsa2
    complexed with bma, man, nag, so4
    1. region b:78-431 [137958] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk