Structural Classification of Proteins
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Protein: Fructose-1,6-bisphosphate aldolase from Human (Homo sapiens), liver isozyme [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: TIM beta/alpha-barrel [51350]
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily: Aldolase [51569]
    Common fold covers whole protein structure
    link to SUPERFAMILY database - Superfamily
  5. Family: Class I aldolase [51570]
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  6. Protein: Fructose-1,6-bisphosphate aldolase [51576]
  7. Species: Human (Homo sapiens), liver isozyme [TaxId: 9606] [51578]

PDB Entry Domains:

  1. 1qo5 picpic
    complexed with so4
    1. chain a [29102] picpiclink
    2. chain b [29103] picpiclink
    3. chain c [29104] picpiclink
    4. chain d [29105] picpiclink
    5. chain e [29106] picpiclink
    6. chain f [29107] picpiclink
    7. chain g [29108] picpiclink
    8. chain h [29109] picpiclink
    9. chain i [29110] picpiclink
    10. chain j [29111] picpiclink
    11. chain k [29112] picpiclink
    12. chain l [29113] picpiclink
    13. chain m [29114] picpiclink
    14. chain n [29115] picpiclink
    15. chain o [29116] picpiclink
    16. chain p [29117] picpiclink
    17. chain q [29118] picpiclink
    18. chain r [29119] picpiclink
  2. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region a:6-342 [121880] picpiclink
  3. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region b:6-343 [121881] picpiclink
  4. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region c:6-343 [121882] picpiclink
  5. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region d:6-342 [121883] picpiclink
  6. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region w:6-343 [121884] picpiclink
  7. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region x:6-343 [121885] picpiclink
  8. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region y:6-343 [121886] picpiclink
  9. 1xdm picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region z:6-342 [121887] picpiclink
  10. 1xdl picpic
    complexed with so4; mutant
    1. region a:6-343 [121872] picpiclink
  11. 1xdl picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region b:6-343 [121873] picpiclink
  12. 1xdl picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region c:6-343 [121874] picpiclink
  13. 1xdl picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region d:6-343 [121875] picpiclink
  14. 1xdl picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region w:6-343 [121876] picpiclink
  15. 1xdl picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region x:6-343 [121877] picpiclink
  16. 1xdl picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region y:6-343 [121878] picpiclink
  17. 1xdl picpic
    automatically matched to 1XDL A:6-343
    complexed with so4; mutant
    1. region z:6-342 [121879] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk