Structural Classification of Proteins
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Fold: SH3-like barrel

barrel, partly opened; n*=4, S*=8; meander
the last strand is interrupted by a turn of 3-10 helix

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: SH3-like barrel [50036]
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix

Superfamilies:

  1. C-terminal domain of transcriptional repressors [50037] (3)
    the N-terminal domains of these repressors bind DNA
    link to SUPERFAMILY database - Superfamily
    1. Biotin repressor (BirA) [50038] (2)
      1. Biotin repressor/biotin holoenzyme synthetase, C-terminal domain [50039]
        1. Escherichia coli [TaxId: 562] [50040] (5) picpic
      2. Biotin--[acetyl-CoA-carboxylase] ligase C-terminal domain [141186]
        1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [141187] (28) picpic
          SQ O57883 189-235
    2. FeoA-like [50041] (4)
      1. Diphtheria toxin repressor (DtxR) [50042]
        1. Corynebacterium diphtheriae [TaxId: 1717] [50043] (15) picpic
          SQ P33120
      2. Iron-dependent regulator IdeR [63742]
        1. Mycobacterium tuberculosis [TaxId: 1773] [63743] (2) picpic
          SQ Q50495
      3. Ferrous iron transport protein A, FeoA [159014]
        1. Klebsiella pneumoniae [TaxId: 573] [159015] (1) picpic
          SQ A6TF31 1-75
      4. Hypothetical protein PA4359 [159016]
        1. Pseudomonas aeruginosa [TaxId: 287] [159017] (1) picpic
          SQ Q9HW42 1-75
    3. Transcriptional repressor protein KorB [69242] (1)
      1. Transcriptional repressor protein KorB [69243]
        1. Escherichia coli [TaxId: 562] [69244] (2) picpic
  2. SH3-domain [50044] (1)
    link to SUPERFAMILY database - Superfamily
    1. SH3-domain [50045] (48)
      1. C-Crk, N-terminal SH3 domain [50046]
        1. Mouse (Mus musculus) [TaxId: 10090] [50047] (9) picpic
      2. Fyn proto-oncogene tyrosine kinase, SH3 domain [50048]
        1. Human (Homo sapiens) [TaxId: 9606] [50049] (11) picpic
      3. SH3 domain from nebulin [50050]
        1. Human (Homo sapiens) [TaxId: 9606] [50051] (2) picpic
      4. Abl tyrosine kinase, SH3 domain [50052]
        1. Mouse (Mus musculus) [TaxId: 10090] [50053] (4) picpic
        2. Human (Homo sapiens) [TaxId: 9606] [50054] (5) picpic
      5. Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055]
        1. Human (Homo sapiens) [TaxId: 9606] [50056] (3) picpic
        2. Cow (Bos taurus) [TaxId: 9913] [50057] (2) picpic
      6. alpha-Spectrin, SH3 domain [50058]
        1. Chicken (Gallus gallus) [TaxId: 9031] [50059] (21) picpic
      7. IL-2 inducible T-cell (Itc) kinase [50060]
        1. Mouse (Mus musculus) [TaxId: 10090] [50061] (1) picpic
      8. Hemapoetic cell kinase Hck [50062]
        1. Human (Homo sapiens) [TaxId: 9606] [50063] (6) picpic
      9. Carboxyl-terminal src kinase (csk) [74654]
        1. Human (Homo sapiens) [TaxId: 9606] [74658] (2) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [74655] (1) picpic
      10. c-src protein tyrosine kinase [50064]
        1. Human (Homo sapiens) [TaxId: 9606] [50065] (5) picpic
        2. Chicken (Gallus gallus) [TaxId: 9031] [50066] (9) picpic
        3. Avian sarcoma virus [TaxId: 11876] [50067] (2) picpic
          v-src
      11. Bruton's tyrosine kinase [50068]
        1. Human (Homo sapiens) [TaxId: 9606] [50069] (3) picpic
        2. Mus musculus [TaxId: 10090] [159018] (2) picpic
      12. tyrosine kinase tec [69246]
        1. Mouse (Mus musculus) [TaxId: 10090] [69247] (1) picpic
      13. Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070]
        1. Human (Homo sapiens) [TaxId: 9606] [50071] (6) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [50072] (5) picpic
        3. Caenorhabditis elegans, SEM-5 [TaxId: 6239] [50073] (5) picpic
          Sex muscle abnormal protein 5
      14. Grb2-related adaptor protein 2 (Mona/Gads) [89293]
        1. Mouse (Mus musculus) [TaxId: 10090] [89294] (5) picpic
      15. Phospholipase C, SH3 domain [50074]
        1. Human (Homo sapiens) [TaxId: 9606] [50075] (2) picpic
      16. p56-lck tyrosine kinase, SH3 domain [50076]
        1. Human (Homo sapiens) [TaxId: 9606] [50077] (10) picpic
      17. 53BP2 [50078]
        1. Human (Homo sapiens) [TaxId: 9606] [50079] (1) picpic
      18. Amphiphysin 2 [50080]
        synonyms: Myc box dependent interacting protein 1, bin1
        1. Rat (Rattus norvegicus) [TaxId: 10116] [50081] (4) picpic
      19. EPS8 SH3 domain [50082]
        1. Mouse (Mus musculus) [TaxId: 10090] [50083] (3) picpic
      20. Vav N-terminal SH3 domain [63744]
        1. Mouse (Mus musculus) [TaxId: 10090] [63745] (3) picpic
      21. Melanoma inhibitory activity protein [63746]
        1. Human (Homo sapiens) [TaxId: 9606] [63747] (3) picpic
      22. Psd-95 [69248]
        associates with a guanylate kinase domain
        1. Rat (Rattus norvegicus) [TaxId: 10116] [69249] (3) picpic
      23. Actin binding protein ABP1 [74920]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [74921] (2) picpic
      24. p47pox (neutrophil cytosolic factor 1) [89295]
        1. Human (Homo sapiens) [TaxId: 9606] [89296] (5) picpic
      25. p67phox [74922]
        1. Human (Homo sapiens) [TaxId: 9606] [74923] (1) picpic
      26. Peroxisomal membrane protein Pex13p [82055]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82056] (5) picpic
      27. Intersectin 2 (KIAA1256) [101669]
        1. Human (Homo sapiens) [TaxId: 9606] [101670] (5) picpic
          SQ Q9NZM3 761-841, 897-957, 982-1037, 1055-1121, 1102-1186
      28. Hypothetical protein Baa76854.1 (KIAA1010) [101671]
        1. Human (Homo sapiens) [TaxId: 9606] [101672] (2) picpic
      29. Olygophrenin-1 like protein (KIAA0621) [101673]
        1. Human (Homo sapiens) [TaxId: 9606] [101674] (1) picpic
      30. Signal transducing adaptor molecule Stam2 [101675]
        1. Mouse (Mus musculus) [TaxId: 10090] [101676] (1) picpic
      31. Rac/CDC42 GEF 6 [101677]
        1. Human (Homo sapiens) [TaxId: 9606] [101678] (1) picpic
      32. Hypothetical protein YFR024c [101679]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [101680] (2) picpic
      33. Fyn-binding protein (T-cell adapter protein adap) [101681]
        1. Human (Homo sapiens) [TaxId: 9606] [101682] (1) picpic
      34. SH3-like domain of the L-type calcium channel [110158]
        1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [110159] (4) picpic
          SQ P54288
        2. Rat (Rattus norvegicus) [TaxId: 10116] [110160] (3) picpic
          SQ P54287 38-362
      35. BAI1-associated protein 2-like 1 (RIKEN cDNA 1300006m19) [110161]
        1. Mouse (Mus musculus) [TaxId: 10090] [110162] (1) picpic
          SQ Q9DBJ3 343-401
      36. Kalirin-9a [117147]
        1. Mouse (Mus musculus) [TaxId: 10090] [117148] (1) picpic
          SQ Q8BTT9 594-651
      37. RIM binding protein 2, RIMBP2 [117149]
        1. Human (Homo sapiens) [TaxId: 9606] [117150] (1) picpic
          SQ O15034 160-242
      38. BZZ1 [141188]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141189] (1) picpic
          SQ P38822 497-552
      39. Nck-2 [159019]
        1. Human (Homo sapiens) [TaxId: 9606] [159020] (1) picpic
          SQ O43639 192-262
          unclassified SH3 domains of this protein species are: 1WX6, 2B86, 2FRW, 2FRY
  3. Prokaryotic SH3-related domain [82057] (4)
    link to SUPERFAMILY database - Superfamily
    1. GW domain [82058] (1)
      1. Internalin B, C-terminal domains [82059]
        duplication: tandem repeat of three SH3-like GW domains
        1. Listeria monocytogenes [TaxId: 1639] [82060] (1) picpic
    2. PhnA-like [141190] (2)
      Pfam 03831
      1. Hypothetical protein PA0128, C-terminal domain [141191]
        1. Pseudomonas aeruginosa [TaxId: 287] [141192] (1) picpic
          SQ Q9I704 40-113
      2. Hypothetical protein RPA4501 [141193]
        1. Rhodopseudomonas palustris [TaxId: 1076] [141194] (1) picpic
          SQ Q6N1A7 1-72
    3. Spr N-terminal domain-like [141195] (1)
      1. Cell wall-associated hydrolase Spr N-terminal domain [141196]
        1. Nostoc punctiforme [TaxId: 272131] [141197] (3) picpic
          SQ Q8YRR4 13-86
    4. Ply C-terminal domain-like [141198] (1)
      duplication: tandem repeat of two SH3-like domains swapped with the N-terminal strands; non-overlapping parts of sequence are covered by PfamB 062324 and PfamB 020199
      1. Endolysin Ply, C-terminal domain [141199]
        1. Bacteriophage Psa [TaxId: 171618] [141200] (1) picpic
          SQ Q8W5Y8 181-314
  4. Myosin S1 fragment, N-terminal domain [50084] (1)
    link to SUPERFAMILY database - Superfamily
    1. Myosin S1 fragment, N-terminal domain [50085] (4)
      1. Myosin S1 fragment, N-terminal domain [50086]
        1. Chicken (Gallus gallus), pectoral muscle [TaxId: 9031] [50087] (4) picpic
        2. Chicken (Gallus gallus), Va isoform [TaxId: 9031] [101683] (3) picpic
        3. Bay scallop (Aequipecten irradians) [TaxId: 31199] [50088] (11) picpic
          SQ P24733 3-836 ! SQ P24733 6-837
        4. Dictyostelium discoideum [TaxId: 44689] [50089] (21) picpic
  5. Tudor/PWWP/MBT [63748] (4)
    link to SUPERFAMILY database - Superfamily
    1. Tudor domain [63749] (7)
      Pfam 00567
      1. Survival motor neuron protein 1, smn [63750]
        1. Human (Homo sapiens) [TaxId: 9606] [63751] (2) picpic
      2. p53-binding protein 1, 53BP1 [110163]
        duplication; contains two Tudor domains in tandem
        1. Human (Homo sapiens) [TaxId: 9606] [110164] (6) picpic
          SQ Q12888 1485-1602 ! SQ Q12888 1484-1606
      3. Tudor domain-containing protein 3, TDRD3 [141201]
        1. Mouse (Mus musculus) [TaxId: 10090] [141202] (1) picpic
          SQ Q91W18 553-612
      4. Jumonji domain-containing protein 2A [141203]
        contains tandem repeat of two segment-swapped Tudor domains
        1. Human (Homo sapiens) [TaxId: 9606] [141204] (20) picpic
          SQ O75164 897-955! SQ O75164 956-1011
      5. Tudor and KH domain-containing protein TDRKH [141205]
        1. Human (Homo sapiens) [TaxId: 9606] [141206] (1) picpic
          SQ Q9Y2W6 329-425
      6. P100 co-activator, SND1 [141207]
        1. Human (Homo sapiens) [TaxId: 9606] [141208] (2) picpic
          SQ Q7KZF4 705-794
      7. Lamin-b receptor [141209]
        1. Human (Homo sapiens) [TaxId: 9606] [141210] (1) picpic
          SQ Q14739 1-55
    2. PWWP domain [69250] (6)
      includes the C-terminal all-alpha subdomain
      1. DNA methyltransferase DNMT3B [69251]
        1. Mouse (Mus musculus) [TaxId: 10090] [69252] (1) picpic
      2. Hypothetical protein SPBC215.07c [89297]
        1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [89298] (1) picpic
      3. Hepatoma-derived growth factor, related protein 3 [101684]
        1. Mouse (Mus musculus) [TaxId: 10090] [101685] (1) picpic
      4. Hepatoma-derived growth factor, HDGF [117151]
        1. Human (Homo sapiens) [TaxId: 9606] [117152] (3) picpic
          SQ P51858 1-100
        2. Rat (Rattus norvegicus) [TaxId: 10116] [141211] (1) picpic
          SQ Q8VHK7 1-110
      5. Histone-lysine N-methyltransferase NSD3 [141212]
        WHSC1L1
        1. Human (Homo sapiens) [TaxId: 9606] [141213] (1) picpic
          SQ Q9BZ95 957-1053
    3. MBT repeat [89299] (4)
      Pfam 02820
      contains extended 'arm', N-terminal to the common fold core
      1. Scml2 protein [89300]
        duplication: contains tandem repeat of two MBT repeats
        1. Human (Homo sapiens) [TaxId: 9606] [89301] (7) picpic
      2. Lethal(3)malignant brain tumor-like protein [101686]
        1. Human (Homo sapiens) [TaxId: 9606] [101687] (3) picpic
      3. Lethal(3)malignant brain tumor-like 3 protein, L3MBTL3 (KIAA1798) [117153]
        1. Human (Homo sapiens) [TaxId: 9606] [117154] (2) picpic
          SQ Q96JM7 259-372, 469-562
      4. Scm-like with four MBT domains protein 2, SFMBT2 (KIAA1617) [117155]
        1. Human (Homo sapiens) [TaxId: 9606] [117156] (1) picpic
          SQ Q5VUG0 181-285
    4. CPH domain [159021] (1)
      1. Cullin-7 [159022]
        1. Human (Homo sapiens) [TaxId: 9606] [159023] (1) picpic
          SQ Q14999 360-435
  6. Chromo domain-like [54160] (3)
    SH3-like barrel is capped by a C-terminal helix
    link to SUPERFAMILY database - Superfamily
    1. "Histone-like" proteins from archaea [54161] (2)
      1. DNA-binding protein [54162]
        1. Archaeon Sulfolobus solfataricus, Sso7d [TaxId: 2287] [54163] (8) picpic
          SQ P61991
        2. Archaeon Sulfolobus acidocaldarius, Sac7d [TaxId: 2285] [54164] (10) picpic
          SQ P13123
    2. Chromo domain [54165] (10)
      lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold
      1. Heterochromatin protein 1, HP1 [54166]
        duplication: consists of two homologous domains, N-terminal chromo domain and C-terminal chromo shadow domain
        1. Mouse (Mus musculus), HP1 beta (MOD1, M31) [TaxId: 10090] [54167] (8) picpic
        2. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [75343] (3) picpic
          SQ P05205 23-74
        3. Fission yeast (Schizosaccharomyces pombe), SWI6 [TaxId: 4896] [54169] (1) picpic
      2. Polycomb protein, Pc [101688]
        1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [101689] (2) picpic
      3. Histone methyltransferase clr4, chromo domain [64217]
        1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [64218] (1) picpic
      4. Chromobox protein homolog 8 [141214]
        Polycomb 3 homolog, Pc3
        1. Mouse (Mus musculus) [TaxId: 10090] [141215] (1) picpic
          SQ Q9QXV1 7-58
      5. CpSRP43 [141216]
        Signal recognition particle 43 kDa protein, chloroplast precursor (CAO)
        1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [141217] (6) picpic
          SQ O22265 265-319! SQ O22265 320-373! SQ O22265 84-128
      6. Chromodomain protein, Y-like isoform [141218]
        1. Human (Homo sapiens) [TaxId: 9606] [141219] (1) picpic
          SQ Q32NC5 1-66
      7. ATP-dependent helicase CHD1 (Chromo domain protein 1) [141220]
        1. Human (Homo sapiens) [TaxId: 9606] [141221] (25) picpic
          SQ O14646 269-366! SQ O14646 270-355! SQ O14646 366-445! SQ O14646 367-443! SQ O14646 367-445
        2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141222] (2) picpic
          SQ P32657 172-252! SQ P32657 249-347
    3. Chromo barrel domain [117157] (3)
      typical SH3-like barrel fold; similar sequence motif to the canonical chromo domain
      1. Probable histone acetyltransferase MYST1 [117158]
        1. Mouse (Mus musculus) [TaxId: 10090] [117159] (1) picpic
          SQ Q9D1P2 49-169
      2. Putative histone acetyltransferase MOF [141223]
        Males-absent on the first protein
        1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [141224] (1) picpic
          SQ O02193 367-454
      3. Mortality factor 4-like protein 1, MRG15 [141225]
        MORF-related gene 15 isoform 1
        1. Human (Homo sapiens) [TaxId: 9606] [141226] (7) picpic
          SQ Q9UBU8 6-88
  7. BAH domain [82061] (1)
    link to SUPERFAMILY database - Superfamily
    1. BAH domain [82062] (1)
      1. Origin-recognition complex protein 120kDa subunit, Orc1p [82063]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82064] (3) picpic
  8. PAZ domain [101690] (1)
    link to SUPERFAMILY database - Superfamily
    1. PAZ domain [101691] (5)
      1. Argonaute 2 [101692]
        1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [101693] (4) picpic
          SQ Q9VUQ5 602-717 ! SQ Q9VUQ5 602-720
      2. Argonaute 1 [101694]
        1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [101695] (1) picpic
      3. Eukaryotic translation initiation factor 2C 1, EIF2C1 [110165]
        1. Human (Homo sapiens) [TaxId: 9606] [110166] (2) picpic
          SQ Q9UL18 225-349
      4. Argonaute homologue PF0537 [110167]
        includes the N-terminal domain
        1. Pyrococcus furiosus [TaxId: 2261] [110168] (3) picpic
          SQ Q8U3D2
      5. Argonaute homologue Aq_1447 [141227]
        includes the N-terminal domain
        1. Aquifex aeolicus [TaxId: 63363] [141228] (6) picpic
          SQ O67434 4-314
  9. Cap-Gly domain [74924] (1)
    link to SUPERFAMILY database - Superfamily
    1. Cap-Gly domain [74925] (12)
      Pfam 01302
      1. Cytoskeleton-associated protein F53F4.3 [74926]
        1. Caenorhabditis elegans [TaxId: 6239] [74927] (2) picpic
          SQ Q20728 132-229
      2. Cylindromatosis tumour-suppressor Cyld [82065]
        1. Human (Homo sapiens) [TaxId: 9606] [82066] (3) picpic
          SQ Q9NQC7 125-206, 228-304, 460-550
      3. Tubulin-specific chaperone B (SKAP1) [117160]
        1. Mouse (Mus musculus) [TaxId: 10090] [117161] (1) picpic
          SQ Q9D1E6 134-233
      4. CLIP170-related 59kda protein CLIPR-59 (1500005P14Rik) [117162]
        1. Mouse (Mus musculus) [TaxId: 10090] [117163] (1) picpic
          SQ Q9DB67 19-107
        2. Human (Homo sapiens) [TaxId: 9606] [141229] (1) picpic
          SQ Q96DZ5 285-366
      5. Restin-like protein 2, Rsnl2 [117164]
        1. Mouse (Mus musculus) [TaxId: 10090] [117165] (2) picpic
          SQ Q8CI96 266-354; 617-696
      6. CLIP-115 [141230]
        1. Human (Homo sapiens) [TaxId: 9606] [141231] (4) picpic
          SQ Q9UDT6 219-289! SQ Q9UDT6 68-149
      7. Centrosome-associated protein 350 [141232]
        1. Human (Homo sapiens) [TaxId: 9606] [141233] (1) picpic
          SQ Q5VT06 2473-2581
      8. Dynactin 1 [141234]
        1. Human (Homo sapiens) [TaxId: 9606] [141235] (6) picpic
          SQ Q14203 1-99! SQ Q14203 25-98
      9. Restin [141236]
        1. Human (Homo sapiens) [TaxId: 9606] [141237] (3) picpic
          SQ P30622 1-128! SQ P30622 181-340
        2. Mouse (Mus musculus) [TaxId: 10090] [141238] (1) picpic
          SQ Q922J3 58-128
      10. Kinesin-like protein kif13b [141239]
        1. Human (Homo sapiens) [TaxId: 9606] [141240] (1) picpic
          SQ Q9NQT8 1684-1771
  10. Electron transport accessory proteins [50090] (4)
    link to SUPERFAMILY database - Superfamily
    1. R67 dihydrofolate reductase [50091] (1)
      1. R67 dihydrofolate reductase [50092]
        1. Escherichia coli, plasmid PLZ1 [TaxId: 562] [50093] (6) picpic
    2. Photosystem I accessory protein E (PsaE) [50094] (4)
      1. Photosystem I accessory protein E (PsaE) [50095]
        1. Cyanobacterium (Synechococcus sp.), pcc 7002 [TaxId: 1131] [50096] (2) picpic
        2. Cyanobacterium (Synechocystis sp.), pcc 6803 [TaxId: 1143] [89302] (1) picpic
        3. Cyanobacterium (Nostoc sp.), strain pcc8009 [TaxId: 1180] [50097] (2) picpic
        4. Synechococcus elongatus [TaxId: 32046] [63752] (1) picpic
    3. Ferredoxin thioredoxin reductase (FTR), alpha (variable) chain [50098] (1)
      1. Ferredoxin thioredoxin reductase (FTR), alpha (variable) chain [50099]
        1. Synechocystis sp. [TaxId: 1143] [50100] (6) picpic
    4. Nitrile hydratase beta chain [50101] (3)
      contains irregular array of helices in the N-terminal extension
      1. Iron-containing nitrile hydratase [50102]
        1. Rhodococcus erythropolis [TaxId: 1833] [50103] (16) picpic
          also Rhodococcus sp. R312
      2. Cobalt-containing nitrile hydratase [82067]
        1. Pseudonocardia thermophila [TaxId: 1848] [82068] (5) picpic
          SQ Q7SID3
        2. Bacillus smithii [TaxId: 1479] [117166] (1) picpic
          SQ Q84FS6 # 85% sequence identity; Bacillus sp. RAPc8 TaxID: 218609
  11. Translation proteins SH3-like domain [50104] (7)
    many known members contain KOW motif
    link to SUPERFAMILY database - Superfamily
    1. Ribosomal proteins L24p and L21e [50105] (5)
      1. Ribosomal proteins L24 (L24p) [50106]
        1. Archaeon Haloarcula marismortui [TaxId: 2238] [50107] (44) picpic
          SQ P10972
        2. Escherichia coli [TaxId: 562] [141241] (30) picpic
          SQ P60624 1-102
        3. Deinococcus radiodurans [TaxId: 1299] [159024] (7) picpic
          SQ Q9RXJ1 4-113
        4. Thermus thermophilus [TaxId: 274] [159025] (11) picpic
          SQ Q72I15 2-102
      2. Ribosomal proteins L21e [50108]
        1. Archaeon Haloarcula marismortui [TaxId: 2238] [50109] (40) picpic
          SQ P12734
    2. eIF5a N-terminal domain-like [50110] (7)
      1. Eukaryotic initiation translation factor 5a (eIF5a) [50111]
        1. Archaeon Methanococcus jannaschii [TaxId: 2190] [50112] (2) picpic
        2. Archaeon Pyrobaculum aerophilum [TaxId: 13773] [50113] (1) picpic
        3. Archaeon Pyrococcus horikoshii [TaxId: 53953] [82069] (1) picpic
        4. Leishmania infantum [TaxId: 5671] [110169] (1) picpic
          SQ Q9N9V6
        5. Leishmania mexicana [TaxId: 5665] [117167] (1) picpic
          SQ Q9N9V6 97% sequence identity
      2. Woronin body major protein (Hex1) [82070]
        1. Filamentous fungi (Neurospora crassa) [TaxId: 5141] [82071] (1) picpic
      3. Elongation factor P N-terminal domain [110170]
        1. Thermus thermophilus HB8 [TaxId: 300852] [110171] (1) picpic
          SQ Q76G20
    3. C-terminal domain of ribosomal protein L2 [50114] (5)
      1. C-terminal domain of ribosomal protein L2 [50115]
        1. Bacillus stearothermophilus [TaxId: 1422] [50116] (2) picpic
        2. Archaeon Haloarcula marismortui [TaxId: 2238] [50117] (40) picpic
          SQ P20276
        3. Thermus thermophilus [TaxId: 274] [159026] (5) picpic
          SQ Q72I07 126-272
        4. Escherichia coli [TaxId: 562] [159027] (27) picpic
          SQ P60422 125-269
        5. Deinococcus radiodurans [TaxId: 1299] [159028] (5) picpic
          SQ Q9RXJ9 128-272
    4. N-utilization substance G protein NusG, C-terminal domain [82072] (2)
      1. N-utilization substance G protein NusG, C-terminal domain [82073]
        1. Aquifex aeolicus [TaxId: 63363] [82074] (3) picpic
        2. Thermus thermophilus [TaxId: 274] [101696] (1) picpic
    5. SPT5 KOW domain-like [141242] (1)
      part of Pfam 00467
      1. Transcription elongation factor SPT5 [141243]
        1. Human (Homo sapiens) [TaxId: 9606] [141244] (1) picpic
          SQ O00267 462-523
    6. Ribosomal protein L19 [141245] (3)
      Pfam 01245
      1. Ribosomal protein L19 [141246]
        1. Escherichia coli [TaxId: 562] [141247] (9) picpic
          SQ P0A7K6 1-114
        2. Deinococcus radiodurans [TaxId: 1299] [159029] (6) picpic
          SQ Q9RWB4 2-109
        3. Thermus thermophilus [TaxId: 274] [159030] (4) picpic
          SQ P60490 1-138
    7. Ribosomal protein L14e [159031] (1)
      PfamB 032577
      1. Ribosomal protein L14e [159032]
        1. Sulfolobus solfataricus [TaxId: 2287] [159033] (1) picpic
          SQ Q980C1 1-96
  12. Cell growth inhibitor/plasmid maintenance toxic component [50118] (3)
    contains insert beta-sheet subdomain and C-terminal helix
    link to SUPERFAMILY database - Superfamily
    1. CcdB [50119] (1)
      1. CcdB [50120]
        topoisomerase poison
        1. Escherichia coli [TaxId: 562] [50121] (6) picpic
    2. Kid/PemK [82075] (3)
      1. Kid toxin protein (ParD) [82076]
        1. Plasmid R1, from Escherichia coli [TaxId: 2482] [82077] (3) picpic
      2. MazF protein [89303]
        1. Escherichia coli [TaxId: 562] [89304] (1) picpic
      3. PemK-like protein YdcE [82078]
        1. Bacillus subtilis [TaxId: 1423] [82079] (1) picpic
    3. Rv2302-like [141248] (1)
      different orientation for the extra C-terminal helix relative the SH3-like barrel
      1. Hypothetical protein Rv2302/MT2359 [141249]
        1. Mycobacterium tuberculosis [TaxId: 1773] [141250] (1) picpic
          SQ P64983 1-80
  13. Fumarylacetoacetate hydrolase, FAH, N-terminal domain [63433] (1)
    link to SUPERFAMILY database - Superfamily
    1. Fumarylacetoacetate hydrolase, FAH, N-terminal domain [63434] (1)
      contains 5 short helices in the loop between the third and fourth strands
      1. Fumarylacetoacetate hydrolase, FAH, N-terminal domain [63435]
        1. Mouse (Mus musculus) [TaxId: 10090] [63436] (6) picpic
  14. DNA-binding domain of retroviral integrase [50122] (1)
    link to SUPERFAMILY database - Superfamily
    1. DNA-binding domain of retroviral integrase [50123] (3)
      1. DNA-binding domain of retroviral integrase [50124]
        1. Human immunodeficiency virus type 1 [TaxId: 11676] [50125] (4) picpic
        2. Rous sarcoma virus RSV [TaxId: 11886] [50126] (2) picpic
        3. Simian immunodeficiency virus [TaxId: 11723] [50127] (1) picpic
  15. Hypothetical protein YfhH [101697] (1)
    contains extra N-terminal all-alpha subdomain
    link to SUPERFAMILY database - Superfamily
    1. Hypothetical protein YfhH [101698] (1)
      1. Hypothetical protein YfhH [101699]
        1. Bacillus subtilis [TaxId: 1423] [101700] (1) picpic
  16. Kinase-associated protein B-like [141251] (1)
    contains extra C-terminal alpha-hairpin
    link to SUPERFAMILY database - Superfamily
    1. Kinase-associated protein B-like [141252] (1)
      1. Kinase-associated protein B [141253]
        1. Bacillus cereus [TaxId: 1396] [141254] (2) picpic
          SQ Q816F1 4-127
          BC4909
  17. YccV-like [141255] (1)
    contains extra C-terminal helix packed against barrel
    link to SUPERFAMILY database - Superfamily
    1. YccV-like [141256] (1)
      1. Hypothetical protein YccV [141257]
        1. Escherichia coli [TaxId: 562] [141258] (1) picpic
          SQ P0AB20 21-114
  18. CarD-like [141259] (1)
    link to SUPERFAMILY database - Superfamily
    1. CarD-like [141260] (1)
      Pfam 02559
      1. Transcription-repair coupling factor, RRCF, middle domain [141261]
        1. Escherichia coli [TaxId: 562] [141262] (2) picpic
          SQ P30958 466-545
  19. Mib/herc2 domain-like [159034] (1)
    1. Mib/herc2 domain [159035] (1)
      Pfam 06701
      1. E3 ubiquitin-protein ligase hectd1 [159036]
        1. Human (Homo sapiens) [TaxId: 9606] [159037] (1) picpic
          SQ Q9ULT8 1268-1340
  20. YorP-like [159038] (1)
    1. YorP-like [159039] (1)
      Pfam 09629
      1. Uncharacterized protein YorP [159040]
        1. Bacillus subtilis [TaxId: 1423] [159041] (1) picpic
          SQ O31898 1-71
  21. Plus3-like [159042] (1)
    1. Plus3 [159043] (1)
      Pfam 03126
      1. RNA polymerase-associated protein RTF1 homolog [159044]
        1. Human (Homo sapiens) [TaxId: 9606] [159045] (2) picpic
          SQ Q92541 307-442! SQ Q92541 313-444
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk