Structural Classification of Proteins

Superfamily: SH3-domain

: uperfamily

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: SH3-like barrel [50036]
barrel, partly opened; n*=4, S*=8; meander
the last strand is interrupted by a turn of 3-10 helix
Superfamily: SH3-domain [50044]
uperfamily

Families:

SH3-domain [50045] (48)
1. C-Crk, N-terminal SH3 domain [50046]
  1. Mouse (Mus musculus) [TaxId: 10090] [50047] (9)
2. Fyn proto-oncogene tyrosine kinase, SH3 domain [50048]
  1. Human (Homo sapiens) [TaxId: 9606] [50049] (11)
3. SH3 domain from nebulin [50050]
  1. Human (Homo sapiens) [TaxId: 9606] [50051] (2)
4. Abl tyrosine kinase, SH3 domain [50052]
  1. Mouse (Mus musculus) [TaxId: 10090] [50053] (4)
  2. Human (Homo sapiens) [TaxId: 9606] [50054] (5)
5. Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055]
  1. Human (Homo sapiens) [TaxId: 9606] [50056] (3)
  2. Cow (Bos taurus) [TaxId: 9913] [50057] (2)
6. alpha-Spectrin, SH3 domain [50058]
  1. Chicken (Gallus gallus) [TaxId: 9031] [50059] (21)
7. IL-2 inducible T-cell (Itc) kinase [50060]
  1. Mouse (Mus musculus) [TaxId: 10090] [50061] (1)
8. Hemapoetic cell kinase Hck [50062]
  1. Human (Homo sapiens) [TaxId: 9606] [50063] (6)
9. Carboxyl-terminal src kinase (csk) [74654]
  1. Human (Homo sapiens) [TaxId: 9606] [74658] (2)
  2. Mouse (Mus musculus) [TaxId: 10090] [74655] (1)
10. c-src protein tyrosine kinase [50064]
  1. Human (Homo sapiens) [TaxId: 9606] [50065] (5)
  2. Chicken (Gallus gallus) [TaxId: 9031] [50066] (9)
  3. Avian sarcoma virus [TaxId: 11876] [50067] (2)
    v-src
11. Bruton's tyrosine kinase [50068]
  1. Human (Homo sapiens) [TaxId: 9606] [50069] (3)
  2. Mus musculus [TaxId: 10090] [159018] (2)
12. tyrosine kinase tec [69246]
  1. Mouse (Mus musculus) [TaxId: 10090] [69247] (1)
13. Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070]
  1. Human (Homo sapiens) [TaxId: 9606] [50071] (6)
  2. Mouse (Mus musculus) [TaxId: 10090] [50072] (5)
  3. Caenorhabditis elegans, SEM-5 [TaxId: 6239] [50073] (5)
    Sex muscle abnormal protein 5
14. Grb2-related adaptor protein 2 (Mona/Gads) [89293]
  1. Mouse (Mus musculus) [TaxId: 10090] [89294] (5)
15. Phospholipase C, SH3 domain [50074]
  1. Human (Homo sapiens) [TaxId: 9606] [50075] (2)
16. p56-lck tyrosine kinase, SH3 domain [50076]
  1. Human (Homo sapiens) [TaxId: 9606] [50077] (10)
17. 53BP2 [50078]
  1. Human (Homo sapiens) [TaxId: 9606] [50079] (1)
18. Amphiphysin 2 [50080]
  synonyms: Myc box dependent interacting protein 1, bin1
  1. Rat (Rattus norvegicus) [TaxId: 10116] [50081] (4)
19. EPS8 SH3 domain [50082]
  1. Mouse (Mus musculus) [TaxId: 10090] [50083] (3)
20. Vav N-terminal SH3 domain [63744]
  1. Mouse (Mus musculus) [TaxId: 10090] [63745] (3)
21. Melanoma inhibitory activity protein [63746]
  1. Human (Homo sapiens) [TaxId: 9606] [63747] (3)
22. Psd-95 [69248]
  associates with a guanylate kinase domain
  1. Rat (Rattus norvegicus) [TaxId: 10116] [69249] (3)
23. Actin binding protein ABP1 [74920]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [74921] (2)
24. p47pox (neutrophil cytosolic factor 1) [89295]
  1. Human (Homo sapiens) [TaxId: 9606] [89296] (5)
25. p67phox [74922]
  1. Human (Homo sapiens) [TaxId: 9606] [74923] (1)
26. Peroxisomal membrane protein Pex13p [82055]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82056] (5)
27. Intersectin 2 (KIAA1256) [101669]
  1. Human (Homo sapiens) [TaxId: 9606] [101670] (5)
    SQ Q9NZM3 761-841, 897-957, 982-1037, 1055-1121, 1102-1186
28. Hypothetical protein Baa76854.1 (KIAA1010) [101671]
  1. Human (Homo sapiens) [TaxId: 9606] [101672] (2)
29. Olygophrenin-1 like protein (KIAA0621) [101673]
  1. Human (Homo sapiens) [TaxId: 9606] [101674] (1)
30. Signal transducing adaptor molecule Stam2 [101675]
  1. Mouse (Mus musculus) [TaxId: 10090] [101676] (1)
31. Rac/CDC42 GEF 6 [101677]
  1. Human (Homo sapiens) [TaxId: 9606] [101678] (1)
32. Hypothetical protein YFR024c [101679]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [101680] (2)
33. Fyn-binding protein (T-cell adapter protein adap) [101681]
  1. Human (Homo sapiens) [TaxId: 9606] [101682] (1)
34. SH3-like domain of the L-type calcium channel [110158]
  1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [110159] (4)
    SQ P54288
  2. Rat (Rattus norvegicus) [TaxId: 10116] [110160] (3)
    SQ P54287 38-362
35. BAI1-associated protein 2-like 1 (RIKEN cDNA 1300006m19) [110161]
  1. Mouse (Mus musculus) [TaxId: 10090] [110162] (1)
    SQ Q9DBJ3 343-401
36. Kalirin-9a [117147]
  1. Mouse (Mus musculus) [TaxId: 10090] [117148] (1)
    SQ Q8BTT9 594-651
37. RIM binding protein 2, RIMBP2 [117149]
  1. Human (Homo sapiens) [TaxId: 9606] [117150] (1)
    SQ O15034 160-242
38. BZZ1 [141188]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141189] (1)
    SQ P38822 497-552
39. Nck-2 [159019]
  1. Human (Homo sapiens) [TaxId: 9606] [159020] (1)
    SQ O43639 192-262
    unclassified SH3 domains of this protein species are: 1WX6, 2B86, 2FRW, 2FRY