Structural Classification of Proteins
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Family: SH3-domain

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: SH3-like barrel [50036]
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. Superfamily: SH3-domain [50044]
    link to SUPERFAMILY database - Superfamily
  5. Family: SH3-domain [50045]

Protein Domains:

  1. C-Crk, N-terminal SH3 domain [50046]
    1. Mouse (Mus musculus) [TaxId: 10090] [50047] (9) picpic
  2. Fyn proto-oncogene tyrosine kinase, SH3 domain [50048]
    1. Human (Homo sapiens) [TaxId: 9606] [50049] (11) picpic
  3. SH3 domain from nebulin [50050]
    1. Human (Homo sapiens) [TaxId: 9606] [50051] (2) picpic
  4. Abl tyrosine kinase, SH3 domain [50052]
    1. Mouse (Mus musculus) [TaxId: 10090] [50053] (4) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [50054] (5) picpic
  5. Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055]
    1. Human (Homo sapiens) [TaxId: 9606] [50056] (3) picpic
    2. Cow (Bos taurus) [TaxId: 9913] [50057] (2) picpic
  6. alpha-Spectrin, SH3 domain [50058]
    1. Chicken (Gallus gallus) [TaxId: 9031] [50059] (21) picpic
  7. IL-2 inducible T-cell (Itc) kinase [50060]
    1. Mouse (Mus musculus) [TaxId: 10090] [50061] (1) picpic
  8. Hemapoetic cell kinase Hck [50062]
    1. Human (Homo sapiens) [TaxId: 9606] [50063] (6) picpic
  9. Carboxyl-terminal src kinase (csk) [74654]
    1. Human (Homo sapiens) [TaxId: 9606] [74658] (2) picpic
    2. Mouse (Mus musculus) [TaxId: 10090] [74655] (1) picpic
  10. c-src protein tyrosine kinase [50064]
    1. Human (Homo sapiens) [TaxId: 9606] [50065] (5) picpic
    2. Chicken (Gallus gallus) [TaxId: 9031] [50066] (9) picpic
    3. Avian sarcoma virus [TaxId: 11876] [50067] (2) picpic
      v-src
  11. Bruton's tyrosine kinase [50068]
    1. Human (Homo sapiens) [TaxId: 9606] [50069] (3) picpic
    2. Mus musculus [TaxId: 10090] [159018] (2) picpic
  12. tyrosine kinase tec [69246]
    1. Mouse (Mus musculus) [TaxId: 10090] [69247] (1) picpic
  13. Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070]
    1. Human (Homo sapiens) [TaxId: 9606] [50071] (6) picpic
    2. Mouse (Mus musculus) [TaxId: 10090] [50072] (5) picpic
    3. Caenorhabditis elegans, SEM-5 [TaxId: 6239] [50073] (5) picpic
      Sex muscle abnormal protein 5
  14. Grb2-related adaptor protein 2 (Mona/Gads) [89293]
    1. Mouse (Mus musculus) [TaxId: 10090] [89294] (5) picpic
  15. Phospholipase C, SH3 domain [50074]
    1. Human (Homo sapiens) [TaxId: 9606] [50075] (2) picpic
  16. p56-lck tyrosine kinase, SH3 domain [50076]
    1. Human (Homo sapiens) [TaxId: 9606] [50077] (10) picpic
  17. 53BP2 [50078]
    1. Human (Homo sapiens) [TaxId: 9606] [50079] (1) picpic
  18. Amphiphysin 2 [50080]
    synonyms: Myc box dependent interacting protein 1, bin1
    1. Rat (Rattus norvegicus) [TaxId: 10116] [50081] (4) picpic
  19. EPS8 SH3 domain [50082]
    1. Mouse (Mus musculus) [TaxId: 10090] [50083] (3) picpic
  20. Vav N-terminal SH3 domain [63744]
    1. Mouse (Mus musculus) [TaxId: 10090] [63745] (3) picpic
  21. Melanoma inhibitory activity protein [63746]
    1. Human (Homo sapiens) [TaxId: 9606] [63747] (3) picpic
  22. Psd-95 [69248]
    associates with a guanylate kinase domain
    1. Rat (Rattus norvegicus) [TaxId: 10116] [69249] (3) picpic
  23. Actin binding protein ABP1 [74920]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [74921] (2) picpic
  24. p47pox (neutrophil cytosolic factor 1) [89295]
    1. Human (Homo sapiens) [TaxId: 9606] [89296] (5) picpic
  25. p67phox [74922]
    1. Human (Homo sapiens) [TaxId: 9606] [74923] (1) picpic
  26. Peroxisomal membrane protein Pex13p [82055]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82056] (5) picpic
  27. Intersectin 2 (KIAA1256) [101669]
    1. Human (Homo sapiens) [TaxId: 9606] [101670] (5) picpic
      SQ Q9NZM3 761-841, 897-957, 982-1037, 1055-1121, 1102-1186
  28. Hypothetical protein Baa76854.1 (KIAA1010) [101671]
    1. Human (Homo sapiens) [TaxId: 9606] [101672] (2) picpic
  29. Olygophrenin-1 like protein (KIAA0621) [101673]
    1. Human (Homo sapiens) [TaxId: 9606] [101674] (1) picpic
  30. Signal transducing adaptor molecule Stam2 [101675]
    1. Mouse (Mus musculus) [TaxId: 10090] [101676] (1) picpic
  31. Rac/CDC42 GEF 6 [101677]
    1. Human (Homo sapiens) [TaxId: 9606] [101678] (1) picpic
  32. Hypothetical protein YFR024c [101679]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [101680] (2) picpic
  33. Fyn-binding protein (T-cell adapter protein adap) [101681]
    1. Human (Homo sapiens) [TaxId: 9606] [101682] (1) picpic
  34. SH3-like domain of the L-type calcium channel [110158]
    1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [110159] (4) picpic
      SQ P54288
    2. Rat (Rattus norvegicus) [TaxId: 10116] [110160] (3) picpic
      SQ P54287 38-362
  35. BAI1-associated protein 2-like 1 (RIKEN cDNA 1300006m19) [110161]
    1. Mouse (Mus musculus) [TaxId: 10090] [110162] (1) picpic
      SQ Q9DBJ3 343-401
  36. Kalirin-9a [117147]
    1. Mouse (Mus musculus) [TaxId: 10090] [117148] (1) picpic
      SQ Q8BTT9 594-651
  37. RIM binding protein 2, RIMBP2 [117149]
    1. Human (Homo sapiens) [TaxId: 9606] [117150] (1) picpic
      SQ O15034 160-242
  38. BZZ1 [141188]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141189] (1) picpic
      SQ P38822 497-552
  39. Nck-2 [159019]
    1. Human (Homo sapiens) [TaxId: 9606] [159020] (1) picpic
      SQ O43639 192-262
      unclassified SH3 domains of this protein species are: 1WX6, 2B86, 2FRW, 2FRY
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk