Structural Classification of Proteins
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Family: Chromo domain

lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: SH3-like barrel [50036]
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. Superfamily: Chromo domain-like [54160]
    SH3-like barrel is capped by a C-terminal helix
    link to SUPERFAMILY database - Superfamily
  5. Family: Chromo domain [54165]
    lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold

Protein Domains:

  1. Heterochromatin protein 1, HP1 [54166]
    duplication: consists of two homologous domains, N-terminal chromo domain and C-terminal chromo shadow domain
    1. Mouse (Mus musculus), HP1 beta (MOD1, M31) [TaxId: 10090] [54167] (8) picpic
    2. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [75343] (3) picpic
      SQ P05205 23-74
    3. Fission yeast (Schizosaccharomyces pombe), SWI6 [TaxId: 4896] [54169] (1) picpic
  2. Polycomb protein, Pc [101688]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [101689] (2) picpic
  3. Histone methyltransferase clr4, chromo domain [64217]
    1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [64218] (1) picpic
  4. Chromobox protein homolog 8 [141214]
    Polycomb 3 homolog, Pc3
    1. Mouse (Mus musculus) [TaxId: 10090] [141215] (1) picpic
      SQ Q9QXV1 7-58
  5. CpSRP43 [141216]
    Signal recognition particle 43 kDa protein, chloroplast precursor (CAO)
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [141217] (6) picpic
      SQ O22265 265-319! SQ O22265 320-373! SQ O22265 84-128
  6. Chromodomain protein, Y-like isoform [141218]
    1. Human (Homo sapiens) [TaxId: 9606] [141219] (1) picpic
      SQ Q32NC5 1-66
  7. ATP-dependent helicase CHD1 (Chromo domain protein 1) [141220]
    1. Human (Homo sapiens) [TaxId: 9606] [141221] (25) picpic
      SQ O14646 269-366! SQ O14646 270-355! SQ O14646 366-445! SQ O14646 367-443! SQ O14646 367-445
    2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141222] (2) picpic
      SQ P32657 172-252! SQ P32657 249-347

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk