Structural Classification of Proteins

Fold: Double-stranded beta-helix

: one turn of helix is made by two pairs of antiparallel strands linked with short turns
has appearance of a sandwich of distinct architecture and jelly-roll topology

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: Double-stranded beta-helix [51181]
one turn of helix is made by two pairs of antiparallel strands linked with short turns
has appearance of a sandwich of distinct architecture and jelly-roll topology

Superfamilies:

RmlC-like cupins [51182] (24)
uperfamily
1. dTDP-sugar isomerase [51183] (9)
  1. dTDP-4-dehydrorhamnose 3,5-epimerase RmlC [51184]
    synonym: dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
    1. Salmonella typhimurium [TaxId: 90371] [51185] (2)
      1. 1dzr
        complexed with gol, so4
        
        chain a [28076]
        chain b [28077]
      2. 1dzt
        complexed with aty, gol, so4, tpe
        
        chain a [28078]
        chain b [28079]
    2. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [51186] (2)
      1. 1ep0
        
        chain a [28080]
      2. 1epz
        complexed with tyd
        
        chain a [28081]
    3. Streptococcus suis [TaxId: 1307] [89402] (7)
      1. 1nxm
        
        chain a [86385]
        chain b [86386]
      2. 2ixl
        automatically matched to d1nzca_
        complexed with ni, trh
        
        region a:2-197 [137772]
      3. 2ixl
        automatically matched to d1nzca_
        complexed with ni, trh
        
        region b:3-197 [137773]
      4. 2ixl
        automatically matched to d1nzca_
        complexed with ni, trh
        
        region c:2-197 [137774]
      5. 2ixl
        automatically matched to d1nzca_
        complexed with ni, trh
        
        region d:2-197 [137775]
      6. 1nyw
        complexed with dau
        
        chain a [86429]
        chain b [86430]
      7. 1nzc
        complexed with ni, tdx
        
        chain a [86445]
        chain b [86446]
        chain c [86447]
        chain d [86448]
    4. Mycobacterium tuberculosis [TaxId: 1773] [101971] (6)
      1. 2ixc
        automatically matched to d1upia_
        complexed with trh
        
        region a:1-198 [137765]
      2. 2ixc
        automatically matched to d1upia_
        complexed with trh
        
        region b:1-198 [137766]
      3. 2ixc
        automatically matched to d1upia_
        complexed with trh
        
        region c:1-198 [137767]
      4. 2ixc
        automatically matched to d1upia_
        complexed with trh
        
        region d:1-198 [137768]
      5. 1upi
        
        chain a [99757]
      6. 1pm7
        complexed with act, gol
        
        chain a [94895]
        chain b [94896]
    5. Pseudomonas aeruginosa [TaxId: 287] [101972] (4)
      1. 2ixh
        automatically matched to d1rtva_
        complexed with trh
        
        region a:1-184 [137769]
      2. 2ixh
        automatically matched to d1rtva_
        complexed with trh
        
        region b:1-184 [137770]
      3. 2ixj
        automatically matched to d1rtva_
        complexed with srt
        
        region a:1-184 [137771]
      4. 1rtv
        complexed with tar
        
        chain a [97822]
    6. Archaeon Sulfolobus tokodaii [TaxId: 111955] [141586] (2)
      SQ Q96Z62 1-176
      1. 1wlt
        
        region a:1-176 [121013]
      2. 1wlt
        automatically matched to 1WLT A:1-176
        
        region b:1-176 [121014]
  2. dTDP-4-keto-6-deoxy-glucose-5-epimerase EvaD [101973]
    1. Amycolatopsis orientalis [TaxId: 31958] [101974] (2)
      SQ O52806
      1. 1oi6
        complexed with gol, tmp
        
        chain a [103940]
        chain b [103941]
      2. 1ofn
        complexed with gol
        
        chain a [92830]
        chain b [92831]
  3. Novobiocin biosynthesis protein NovW [141587]
    1. Streptomyces caeruleus [TaxId: 195949] [141588] (1)
      SQ Q9L9E5 1-190
      1. 2c0z
        complexed with edo, so4
        
        region a:1-190 [129615]
  4. dTDP-6-deoxy-3,4-keto-hexulose isomerase FdtA [159287]
    1. Aneurinibacillus thermoaerophilus [TaxId: 143495] [159288] (8)
      SQ Q6T1W8 1-136! SQ Q6T1W8 2-136
      1. 2pa7
        complexed with cl, edo, tyd
        
        region a:2-136 [149339]
      2. 2pa7
        automatically matched to 2PA7 A:2-136
        complexed with cl, edo, tyd
        
        region b:2-135 [149340]
      3. 2pak
        complexed with tyd; mutant
        
        region a:2-136 [149346]
      4. 2pae
        complexed with tyd; mutant
        
        region a:1-136 [149341]
      5. 2pam
        complexed with tyd; mutant
        
        region a:2-136 [149348]
      6. 2pae
        automatically matched to 2PAE A:1-136
        complexed with tyd; mutant
        
        region b:2-135 [149342]
      7. 2pak
        automatically matched to 2PAK A:2-136
        complexed with tyd; mutant
        
        region b:2-135 [149347]
      8. 2pam
        automatically matched to 2PAM A:2-136
        complexed with tyd; mutant
        
        region b:2-135 [149349]
2. Glucose-6-phosphate isomerase, GPI [89403] (2)
  1. Glucose-6-phosphate isomerase, GPI [89404]
    Type II phosphoglucose isomerase
    1. Archaeon Pyrococcus furiosus [TaxId: 2261] [89405] (6)
      SQ P83194
      1. 1x82
        complexed with pa5
        
        chain a [114955]
      2. 1x7n
        complexed with mn, pa5
        
        chain a [114933]
      3. 1qxr
        complexed with ni, pa5
        
        chain a [96552]
        chain b [96553]
      4. 1qxj
        complexed with ni
        
        chain a [96530]
        chain b [96531]
      5. 1qy4
        complexed with 6pg, ni
        
        chain a [96571]
        chain b [96572]
      6. 1x8e
        
        chain a [114958]
        chain b [114959]
    2. Archaeon Thermococcus litoralis [TaxId: 2265] [101975] (11)
      1. 2gc0
        automatically matched to d1j3pa_
        complexed with pan, zn
        
        region a:0-186 [134926]
      2. 2gc0
        automatically matched to d1j3pa_
        complexed with pan, zn
        
        region b:0-186 [134927]
      3. 2gc1
        automatically matched to d1j3pa_
        complexed with s6p, zn
        
        region a:0-186 [134928]
      4. 2gc1
        automatically matched to d1j3pa_
        complexed with s6p, zn
        
        region b:0-186 [134929]
      5. 2gc3
        automatically matched to d1j3pa_
        complexed with m6p, zn
        
        region a:0-186 [134932]
      6. 2gc3
        automatically matched to d1j3pa_
        complexed with m6p, zn
        
        region b:0-186 [134933]
      7. 1j3q
        complexed with fe
        
        chain a [90821]
        chain b [90822]
      8. 1j3p
        complexed with fe
        
        chain a [90819]
        chain b [90820]
      9. 2gc2
        automatically matched to d1j3pa_
        complexed with fpc, zn
        
        region a:0-186 [134930]
      10. 2gc2
        automatically matched to d1j3pa_
        complexed with fpc, zn
        
        region b:0-186 [134931]
      11. 1j3r
        complexed with 6pg, fe
        
        chain a [90823]
        chain b [90824]
3. Hypothetical protein TM1112 [89406] (1)
  1. Hypothetical protein TM1112 [89407]
    1. Thermotoga maritima [TaxId: 2336] [89408] (2)
      1. 1o5u
        structural genomics
        complexed with unl
        
        chain a [92518]
        chain b [92519]
      2. 1lkn
        structural genomics
        
        chain a [84624]
4. TM1287-like [89409] (4)
  1. Hypothetical protein TM1287 [89410]
    1. Thermotoga maritima [TaxId: 2336] [89411] (1)
      1. 1o4t
        structural genomics
        complexed with mn, oxl
        
        chain a [86622]
        chain b [86623]
  2. Hypothetical protein TTHA0104 [117310]
    1. Thermus thermophilus [TaxId: 274] [117311] (3)
      SQ Q5SM39
      1. 1v70
        Structural genomics target
        complexed with na
        
        chain a [113555]
      2. 2dct
        complexed with cl, na
        
        region a:1-105 [131386]
      3. 2dct
        automatically matched to 2DCT A:1-105
        complexed with cl, na
        
        region b:1-105 [131387]
  3. Hypothetical protein TM1010 [141589]
    1. Thermotoga maritima [TaxId: 2336] [141590] (4)
      SQ Q9X0A3 2-135
      1. 2f4p
        complexed with edo, unl
        
        region a:2-135 [132933]
      2. 2f4p
        automatically matched to 2F4P A:2-135
        complexed with edo, unl
        
        region b:4-135 [132934]
      3. 2f4p
        automatically matched to 2F4P A:2-135
        complexed with edo, unl
        
        region c:3-135 [132935]
      4. 2f4p
        automatically matched to 2F4P A:2-135
        complexed with edo, unl
        
        region d:3-135 [132936]
  4. Hypothetical protein SPy1581 [141591]
    1. Streptococcus pyogenes [TaxId: 1314] [141592] (1)
      SQ Q99YR1 1-112
      1. 1yhf
        
        region a:1-112 [123176]
5. TM1459-like [101976] (2)
  1. Hypothetical protein TM1459 [101977]
    1. Thermotoga maritima [TaxId: 2336] [101978] (1)
      1. 1vj2
        structural genomics
        complexed with mn, unl
        
        chain a [100796]
        chain b [100797]
  2. Hydroxypropylphosphonic acid epoxidase Fom4, C-terminal domain [141593]
    1. Streptomyces wedmorensis [TaxId: 43759] [141594] (20)
      SQ Q56185 77-198
      1. 2bnm
        automatically matched to 1ZZ6 A:77-198
        complexed with so4, zn
        
        region a:77-198 [128836]
      2. 2bnm
        automatically matched to 1ZZ6 A:77-198
        complexed with so4, zn
        
        region b:77-198 [128838]
      3. 2bno
        automatically matched to 1ZZ6 A:77-198
        complexed with hg, so4, zn
        
        region a:77-198 [128844]
      4. 2bno
        automatically matched to 1ZZ6 A:77-198
        complexed with hg, so4, zn
        
        region b:77-198 [128846]
      5. 1zzc
        automatically matched to 1ZZ6 A:77-198
        complexed with co, trs
        
        region a:77-198 [125897]
      6. 1zzc
        automatically matched to 1ZZ6 A:77-198
        complexed with co, trs
        
        region b:77-198 [125899]
      7. 1zz7
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, s0h
        
        region a:77-198 [125877]
      8. 1zz7
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, s0h
        
        region b:77-198 [125879]
      9. 1zz6
        
        region a:77-198 [125873]
      10. 1zz6
        automatically matched to 1ZZ6 A:77-198
        
        region b:77-198 [125875]
      11. 1zz8
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, s0h
        
        region a:77-198 [125881]
      12. 1zz8
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, s0h
        
        region b:77-198 [125883]
      13. 1zz8
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, s0h
        
        region c:77-198 [125885]
      14. 2bnn
        automatically matched to 1ZZ6 A:77-198
        complexed with fcn, zn
        
        region a:77-198 [128840]
      15. 2bnn
        automatically matched to 1ZZ6 A:77-198
        complexed with fcn, zn
        
        region b:77-198 [128842]
      16. 1zzb
        automatically matched to 1ZZ6 A:77-198
        complexed with co, s0h
        
        region a:77-198 [125893]
      17. 1zzb
        automatically matched to 1ZZ6 A:77-198
        complexed with co, s0h
        
        region b:77-198 [125895]
      18. 1zz9
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, so4
        
        region a:77-198 [125887]
      19. 1zz9
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, so4
        
        region b:77-198 [125889]
      20. 1zz9
        automatically matched to 1ZZ6 A:77-198
        complexed with fe2, so4
        
        region c:77-198 [125891]
6. Germin/Seed storage 7S protein [51187] (9)
  1. Germin [63853]
    Metal (manganese)-binding protein with oxalate oxidase and superoxide dismutase activities; homohexamer
    1. Barley (Hordeum vulgare) [TaxId: 4513] [63854] (5)
      1. 2et1
        automatically matched to d1fi2a_
        complexed with glv, mn
        
        region a:1-201 [132351]
      2. 1fi2
        complexed with mn
        
        chain a [59845]
      3. 2et7
        complexed with mn; mutant
        
        region a:1-201 [132352]
      4. 2ete
        complexed with glv, mn, nag
        
        region a:1-201 [132354]
      5. 2ete
        automatically matched to 2ETE A:1-201
        complexed with glv, mn, nag
        
        region b:1-201 [132355]
  2. Auxin binding protein [75030]
    1. Maize (Zea mays) [TaxId: 4577] [75031] (2)
      1. 1lrh
        complexed with man, nag, nla, zn; mutant
        
        chain a [74219]
        chain b [74220]
        chain c [74221]
        chain d [74222]
      2. 1lr5
        complexed with man, nag, zn; mutant
        
        chain a [74215]
        chain b [74216]
        chain c [74217]
        chain d [74218]
  3. Seed storage 7S protein [51188]
    duplication: consists of two germin-like domains spatially arranged as subunits in the RmlC dimer; trimer is similar to the germin hexamer
    1. French bean (Phaseolus vulgaris), phaseolin [TaxId: 3885] [51189] (2)
      1. 2phl
        complexed with nag, po4
        
        region a:11-210 [28082]
        region a:220-381 [28083]
        region b:11-210 [28084]
        region b:220-381 [28085]
        region c:10-210 [28086]
        region c:220-381 [28087]
      2. 1phs
        CA-atoms only
        
        region a:11-212 [28088]
        region a:220-381 [28089]
    2. Jack bean (Canavalia ensiformis), canavalin/vinculin [TaxId: 3823] [51190] (8)
      1. 1dgw
        
        chain a [28090]
        chain x,y [28091]
      2. 2cau
        
        region a:46-223 [28092]
        region a:246-421 [28093]
      3. 1dgr
        
        chain a [28096]
        chain x,y [28097]
        chain b [28098]
        chain v,w [28099]
        chain c [28100]
        chain n,m [144355]
      4. 2cav
        
        region a:46-225 [28094]
        region a:246-422 [28095]
      5. 1cau
        
        chain a [28102]
        chain b [28103]
      6. 1cax
        
        chain a [28104]
        chain b [28105]
        chain c [28106]
        chain d [28107]
        chain e [28108]
        chain f [28109]
      7. 1cav
        
        chain a [28110]
        chain b [28111]
      8. 1caw
        
        chain a [28112]
        chain b [28113]
    3. Soybean (Glycine max), proglycinin [TaxId: 3847] [69345] (3)
      1. 1fxz
        
        region a:10-248 [65059]
        region a:297-470 [65060]
        region b:10-248 [65061]
        region b:297-470 [65062]
        region c:10-248 [65063]
        region c:297-470 [65064]
      2. 1ucx
        mutant
        
        region a:14-248 [99192]
        region a:297-470 [99193]
        region b:14-248 [99194]
        region b:297-470 [99195]
        region c:14-248 [99196]
        region c:297-470 [99197]
      3. 1ud1
        mutant
        
        region a:10-248 [99202]
        region a:297-470 [99203]
        region b:10-248 [99204]
        region b:297-470 [99205]
        region c:10-248 [99206]
        region c:297-470 [99207]
    4. Soybean (Glycine max), beta-conglycinin beta subunit [TaxId: 3847] [109608] (3)
      SQ P25974
      1. 1uij
        mutant
        
        region a:6-175 [107866]
        region a:183-392 [107867]
        region b:6-175 [107868]
        region b:183-392 [107869]
        region c:6-175 [107870]
        region c:183-392 [107871]
        region d:6-175 [107872]
        region d:183-392 [107873]
        region e:6-175 [107874]
        region e:183-392 [107875]
        region f:6-175 [107876]
        region f:183-392 [107877]
      2. 1ipj
        complexed with nag
        
        region a:9-176 [71258]
        region a:183-393 [71259]
        region b:9-175 [71260]
        region b:186-393 [71261]
        region c:9-177 [71262]
        region c:181-393 [71263]
      3. 1ipk
        
        region a:8-174 [71264]
        region a:183-392 [71265]
        region b:9-174 [71266]
        region b:183-392 [71267]
        region c:3-180 [71268]
        region c:181-392 [71269]
    5. Soybean (Glycine max), glycinin A3B4 [TaxId: 3847] [89412] (1)
      1. 1od5
        complexed with co3, mg
        
        region a:7-251 [86832]
        region a:321-493 [86833]
        region b:7-251 [86834]
        region b:321-493 [86835]
    6. Soybean (Glycine max), beta-conglycinin alpha prime subunit [TaxId: 3847] [110313] (1)
      SQ Q7XXT2 204-621
      1. 1uik
        complexed with mg
        
        region a:148-350 [107878]
        region a:351-535 [107879]
        region b:148-350 [107880]
        region b:351-535 [107881]
        region c:148-350 [107882]
        region c:351-535 [107883]
  4. Oxalate decarboxylase OxdC (YvrK) [75033]
    duplication: consists of two germin-like metal-ion binding domains
    1. Bacillus subtilis [TaxId: 1423] [75034] (3)
      1. 1j58
        complexed with fmt, mg, mn, mse
        
        chain a [71531]
      2. 1uw8
        complexed with mn, trs
        
        chain a [100100]
      3. 1l3j
        complexed with fmt, mg, mn
        
        chain a [73538]
7. YlbA-like [101979] (4)
  Pfam 05899; formerly pfam06038; duplication: consists of two germin-like domains
  1. Hypothetical protein YlbA [101980]
    1. Escherichia coli [TaxId: 562] [101981] (1)
      1. 1rc6
        structural genomics
        
        chain a [97287]
        chain b [97288]
  2. Glyoxylate-induced protein PA1140 [101982]
    1. Pseudomonas aeruginosa [TaxId: 287] [101983] (1)
      1. 1sq4
        structural genomics; NESG target PAR14
        complexed with scn
        
        chain a [98962]
        chain b [98963]
  3. Hypothetical protein EF2996 [110314]
    1. Enterococcus faecalis [TaxId: 1351] [110315] (1)
      SQ Q82ZQ3
      1. 1sef
        Structural genomics target
        
        chain a [105452]
  4. Hypothetical protein DR1152 [110316]
    1. Deinococcus radiodurans [TaxId: 1299] [110317] (1)
      SQ Q9RV77
      1. 1sfn
        Structural genomics target
        
        chain a [105496]
        chain b [105497]
8. Pirin-like [101984] (2)
  Share a common two-domain fold with the 7S protein; there is a metal-binding site in the N-terminal domain similar to the metal-binding site of germin
  1. Pirin [101985]
    Bcl-3 and nuclear factor I-interacting protein
    1. Human (Homo sapiens) [TaxId: 9606] [101986] (1)
      1. 1j1l
        complexed with fe2
        
        chain a [90766]
  2. Hypothetical protein YhhW [141595]
    1. Escherichia coli [TaxId: 562] [141596] (1)
      SQ P46852 1-231
      1. 1tq5
        complexed with cd
        
        region a:1-231 [119311]
9. Quercetin 2,3-dioxygenase-like [75035] (2)
  Share a common two-domain fold with the 7S protein; there is a metal-binding site in the N-terminal domain similar to the metal-binding site of germin
  1. Quercetin 2,3-dioxygenase [75036]
    1. Aspergillus japonicus [TaxId: 34381] [75037] (5)
      1. 1juh
        complexed with cu, edo, man, nag
        
        chain a [71884]
        chain b [71885]
        chain c [71886]
        chain d [71887]
      2. 1gqg
        complexed with cu, dcd, man, nag
        
        chain a [70352]
        chain b [70353]
        chain c [70354]
        chain d [70355]
      3. 1h1i
        complexed with cu, mpd, nag, que
        
        chain a [76469]
        chain b [76470]
        chain c [76471]
        chain d [76472]
      4. 1h1m
        complexed with bma, cu, kmp, man, mpd, nag
        
        chain a [76473]
        chain b [76474]
        chain c [76475]
        chain d [76476]
      5. 1gqh
        complexed with cu, koj, man, nag
        
        chain a [70356]
        chain b [70357]
        chain c [70358]
        chain d [70359]
  2. Hypothetical protein YxaG [141597]
    1. Bacillus subtilis [TaxId: 1423] [141598] (2)
      SQ P42106 5-334
      1. 1y3t
        complexed with fe
        
        region a:5-334 [122600]
      2. 1y3t
        automatically matched to 1Y3T A:5-334
        complexed with fe
        
        region b:5-334 [122601]
10. Type I phosphomannose isomerase [51191] (3)
  Share a common two-domain fold with the 7S protein; there is a metal-binding site in the N-terminal domain similar to the metal-binding site of germin
  1. Phosphomannose isomerase [51192]
    1. Yeast (Candida albicans) [TaxId: 5476] [51193] (1)
      contains insert all-alpha subdomain; residues 152-266
      1. 1pmi
        complexed with zn
        
        chain a [28114]
  2. Mannose-6-phosphate isomerase ManA [101987]
    1. Bacillus subtilis [TaxId: 1423] [101988] (1)
      1. 1qwr
        complexed with act, fmt, so4, zn
        
        chain a [96491]
        chain b [96492]
  3. Putative mannosephosphate isomerase AF0035 [141599]
    1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [141600] (1)
      SQ O30200 1-299
      1. 1zx5
        complexed with acy, edo, gol, lfr
        
        region a:1-299 [125763]
11. Homogentisate dioxygenase [51194] (1)
  Share a common two-domain fold with the 7S protein; there is a metal-binding site in the C-terminal domain similar to the metal-binding site of germin
  1. Homogentisate dioxygenase [51195]
    1. Human (Homo sapiens) [TaxId: 9606] [51196] (2)
      1. 1eyb
        
        chain a [28115]
      2. 1ey2
        complexed with fe2
        
        chain a [28116]
12. Acireductone dioxygenase [82191] (2)
  1. Acireductone dioxygenase [82192]
    1. Klebsiella pneumoniae [TaxId: 573] [82193] (1)
      NMR-derived model
      1. 1zrr
        automatically matched to d1m4oa_
        complexed with ni
        
        region a:1-179 [125555]
    2. Mouse (Mus musculus) [TaxId: 10090] [141601] (1)
      SQ Q99JT9 1-179
      1. 1vr3
        complexed with ipa, ni, unl
        
        region a:1-179 [120431]
13. KduI-like [110318] (2)
  Pfam 04962: duplication: consists of two germin-like domains
  1. 5-keto-4-deoxyuronate isomerase KduI [110319]
    1. Escherichia coli [TaxId: 562] [110320] (3)
      SQ Q46938 1-266
      1. 1xru
        complexed with 1pe, zn
        
        region a:1-277 [122262]
      2. 1xru
        automatically matched to 1XRU A:1-277
        complexed with 1pe, zn
        
        region b:1-277 [122263]
      3. 1x8m
        
        chain a [109516]
        chain b [109517]
        chain c [109518]
        chain d [109519]
        chain e [109520]
        chain f [109521]
    2. Enterococcus faecalis [TaxId: 1351] [141602] (6)
      SQ Q838L9 1-260
      1. 1ywk
        
        region a:1001-1260 [124155]
      2. 1ywk
        automatically matched to 1YWK A:1001-1260
        
        region b:1001-1260 [124156]
      3. 1ywk
        automatically matched to 1YWK A:1001-1260
        
        region c:1001-1259 [124157]
      4. 1ywk
        automatically matched to 1YWK A:1001-1260
        
        region d:1001-1260 [124158]
      5. 1ywk
        automatically matched to 1YWK A:1001-1260
        
        region e:1001-1260 [124159]
      6. 1ywk
        automatically matched to 1YWK A:1001-1260
        
        region f:1001-1260 [124160]
14. Ureidoglycolate hydrolase AllA [117312] (3)
  Pfam 04115; beta-hairpin-swapped dimeric protein of the germin-like fold
  1. Ureidoglycolate hydrolase AllA [117313]
    1. Shigella flexneri [TaxId: 623] [117314] (2)
      SQ P77731 ! SQ P63487
      1. 1xsq
        
        chain a [115999]
        chain b [116000]
      2. 1xsr
        
        chain a [116001]
        chain b [116002]
    2. Pseudomonas putida [TaxId: 303] [141603] (2)
      SQ P59285 1-166
      1. 2bdr
        complexed with na
        
        region a:1-166 [128342]
      2. 2bdr
        automatically matched to 2BDR A:1-166
        complexed with na
        
        region b:1-166 [128343]
    3. Escherichia coli [TaxId: 562] [141604] (2)
      SQ P63486 1-160
      1. 1yqc
        complexed with glv
        
        region a:1-160 [123877]
      2. 1yqc
        automatically matched to 1YQC A:1-160
        complexed with glv
        
        region b:1-160 [123878]
15. Probable transcriptional regulator VC1968, C-terminal domain [117315] (1)
  1. Probable transcriptional regulator VC1968, C-terminal domain [117316]
    1. Vibrio cholerae [TaxId: 666] [117317] (1)
      SQ Q9KQN0
      1. 1y9q
        Structural genomics target
        complexed with med, zn
        
        region a:83-181 [116593]
16. YML079-like [117318] (3)
  Pfam 06172; DUF985
  1. Hypothetical protein YML079W [117319]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [117320] (2)
      SQ Q03629
      1. 1xe7
        structural genomics target
        complexed with acy, edo, gun
        
        chain a [115213]
        chain b [115214]
        chain c [115215]
      2. 1xe8
        Structural genomics target
        complexed with ade, cit, gol
        
        chain a [115216]
        chain b [115217]
        chain c [115218]
  2. Hypothetical protein Atu3615 [141605]
    1. Agrobacterium tumefaciens [TaxId: 358] [141606] (7)
      SQ Q8U9W0 4-143
      1. 1znp
        
        region a:4-143 [125394]
      2. 1znp
        automatically matched to 1ZNP A:4-143
        
        region b:5-143 [125395]
      3. 1znp
        automatically matched to 1ZNP A:4-143
        
        region c:5-142 [125396]
      4. 1znp
        automatically matched to 1ZNP A:4-143
        
        region d:5-142 [125397]
      5. 1znp
        automatically matched to 1ZNP A:4-143
        
        region e:5-143 [125398]
      6. 1znp
        automatically matched to 1ZNP A:4-143
        
        region f:5-143 [125399]
      7. 1znp
        automatically matched to 1ZNP A:4-143
        
        region g:5-143 [125400]
  3. Hypothetical protein SO0799 [141607]
    1. Shewanella oneidensis [TaxId: 70863] [141608] (10)
      SQ Q8EIN8 1-158
      1. 1yud
        
        region a:1-158 [124046]
      2. 1yud
        automatically matched to 1YUD A:1-158
        
        region b:1-158 [124047]
      3. 1yud
        automatically matched to 1YUD A:1-158
        
        region c:1-158 [124048]
      4. 1yud
        automatically matched to 1YUD A:1-158
        
        region d:1-158 [124049]
      5. 1yud
        automatically matched to 1YUD A:1-158
        
        region e:1-158 [124050]
      6. 1yud
        automatically matched to 1YUD A:1-158
        
        region f:1-158 [124051]
      7. 1yud
        automatically matched to 1YUD A:1-158
        
        region g:1-158 [124052]
      8. 1yud
        automatically matched to 1YUD A:1-158
        
        region h:1-158 [124053]
      9. 1yud
        automatically matched to 1YUD A:1-158
        
        region i:1-158 [124054]
      10. 1yud
        automatically matched to 1YUD A:1-158
        
        region j:1-158 [124055]
17. PA5104-like [141609] (1)
  Pfam 05962; DUF886; duplication: consists of two germin-like domains; overall structural similarity to the YlbA-like family (scop_fa 101979) except a deletion in the interdomain linker region
  1. Hypothetical protein PA5104 [141610]
    1. Pseudomonas aeruginosa [TaxId: 287] [141611] (4)
      SQ Q9HU79 2-196
      1. 1yll
        
        region a:2-196 [123653]
      2. 1yll
        automatically matched to 1YLL A:2-196
        
        region b:3-196 [123654]
      3. 1yll
        automatically matched to 1YLL A:2-196
        
        region c:2-195 [123655]
      4. 1yll
        automatically matched to 1YLL A:2-196
        
        region d:3-196 [123656]
18. MJ0764-like [141612] (1)
  1. Hypothetical protein MJ0764 [141613]
    1. Archaeon Methanococcus jannaschii [TaxId: 2190] [141614] (1)
      SQ Q58174 1-108
      1. 2b8m
        complexed with cl, edo, so4
        
        region a:1-108 [128092]
19. Cysteine dioxygenase type I [141615] (4)
  Pfam 05995, CDO_I
  1. Cysteine dioxygenase type I [141616]
    1. Mouse (Mus musculus) [TaxId: 10090] [141617] (4)
      SQ P60334 5-190
      1. 2b5h
        automatically matched to 2ATF A:5-190
        complexed with fe
        
        region a:5-190 [127894]
      2. 2gh2
        automatically matched to 2ATF A:5-190
        complexed with fe, so4
        
        region a:5-190 [135172]
      3. 2atf
        complexed with edo, ni
        
        region a:5-190 [127290]
      4. 2q4s
        automatically matched to 2ATF A:5-190
        complexed with edo, ni
        
        region a:5-190 [139877]
    2. Ralstonia eutropha [TaxId: 106590] [159289] (1)
      SQ Q46R41 11-202
      1. 2gm6
        complexed with edo, fe, so4
        
        region a:11-202 [147130]
    3. Human (Homo sapiens) [TaxId: 9606] [159290] (1)
      SQ Q16878 6-190
      1. 2ic1
        complexed with cys, fe2
        
        region a:6-190 [147600]
    4. Rattus norvegicus [TaxId: 10116] [159291] (1)
      1. 3eln
        automatically matched to d2atfa1
        complexed with 2co, fe2
        
        region a:5-190 [158185]
20. 3-hydroxyanthranilic acid dioxygenase-like [141618] (2)
  Pfam 06052; 3-HAO
  1. 3-hydroxyanthranilate-3,4-dioxygenase [141619]
    1. Ralstonia metallidurans [TaxId: 119219] [141620] (4)
      SQ Q1LCS4 1-174
      1. 1yfu
        complexed with cl, fe, trs
        
        region a:1-174 [123094]
      2. 1yfw
        automatically matched to 1YFU A:1-174
        complexed with 4aa, fe, oxy, trs
        
        region a:1-174 [123095]
      3. 1yfx
        automatically matched to 1YFU A:1-174
        complexed with 4aa, fe, no, trs
        
        region a:1-174 [123096]
      4. 1yfy
        automatically matched to 1YFU A:1-174
        complexed with 3ha, fe, trs
        
        region a:1-174 [123097]
    2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [159292] (2)
      SQ P47096 1-175
      1. 1zvf
        complexed with ni
        
        region a:1-175 [146029]
      2. 1zvf
        automatically matched to 1ZVF A:1-175
        complexed with ni
        
        region b:1-171 [146030]
21. Acetylacetone-cleaving enzyme-like [159293] (1)
  PfamB 026844
  1. Putative acetyl/propionyl-CoA carboxylase subunit alpha Mpe_A3659 [159294]
    1. Rubrivivax gelatinosus [TaxId: 28068] [159295] (2)
      SQ A2SM23 1-144
      1. 2o1q
        complexed with act, cl, pg4, zn
        
        region a:1-144 [148547]
      2. 2o1q
        automatically matched to 2O1Q A:1-144
        complexed with act, cl, pg4, zn
        
        region b:1-144 [148548]
22. VPA0057-like [159296] (1)
  Pfam 06865; DUF1255; non-canonical dimerisation mode
  1. Uncharacterized protein VPA0057 [159297]
    1. Vibrio parahaemolyticus [TaxId: 670] [159298] (1)
      SQ Q87K41 2-94
      1. 2oyz
        
        region a:2-94 [149082]
23. Gentisate 1,2-dioxygenase-like [159299] (3)
  Share a common two-domain fold with the 7S protein; there is a metal-binding site in the N-terminal domain similar to the metal-binding site of germin; homotetramer
  1. Gentisate 1,2-dioxygenase [159300]
    Salicylate 1,2-dioxygenase
    1. Escherichia coli [TaxId: 562] [159301] (4)
      SQ Q8X655 35-342
      1. 2d40
        complexed with fe
        
        region a:35-342 [146454]
      2. 2d40
        automatically matched to 2D40 A:35-342
        complexed with fe
        
        region b:36-341 [146455]
      3. 2d40
        automatically matched to 2D40 A:35-342
        complexed with fe
        
        region c:35-342 [146456]
      4. 2d40
        automatically matched to 2D40 A:35-342
        complexed with fe
        
        region d:35-342 [146457]
    2. Silicibacter pomeroyi [TaxId: 89184] [159302] (2)
      SQ Q5LLB1 19-373
      1. 3bu7
        complexed with fe2
        
        region a:19-373 [155593]
      2. 3bu7
        automatically matched to 3BU7 A:19-373
        complexed with fe2
        
        region b:19-373 [155594]
    3. Pseudaminobacter salicylatoxidans [TaxId: 93369] [159303] (4)
      SQ Q67FT0 17-367
      1. 2phd
        complexed with act, cl, fe
        
        region a:17-367 [149468]
      2. 2phd
        automatically matched to 2PHD A:17-367
        complexed with act, cl, fe
        
        region b:17-367 [149469]
      3. 2phd
        automatically matched to 2PHD A:17-367
        complexed with act, cl, fe
        
        region c:17-367 [149470]
      4. 2phd
        automatically matched to 2PHD A:17-367
        complexed with act, cl, fe
        
        region d:17-366 [149471]
24. EutQ-like [159304] (1)
  Pfam 06249
  1. Ethanolamine utilization protein EutQ [159305]
    1. Salmonella typhimurium [TaxId: 90371] [159306] (2)
      SQ Q9ZFV5 100-227
      1. 2pyt
        
        region a:100-227 [149957]
      2. 2pyt
        automatically matched to 2PYT A:100-227
        
        region b:103-225 [149958]
Clavaminate synthase-like [51197] (13)
Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
uperfamily
1. Penicillin synthase-like [51198] (4)
  common fold is rather distorted
  1. Isopenicillin N synthase [51199]
    1. Emericella nidulans [TaxId: 162425] [51200] (29)
      SQ P05326
      1. 1odm
        complexed with asv, fe2, so4
        
        chain a [86875]
      2. 2ivi
        automatically matched to d1bk0__
        complexed with acw, fe2, so4
        
        region b:3-331 [137723]
      3. 2bjs
        automatically matched to d1bk0__
        complexed with acv, fe, mee, so4; mutant
        
        region a:3-322 [128632]
      4. 2bu9
        automatically matched to d1bk0__
        complexed with fe, hfv, so4
        
        region a:3-331 [129169]
      5. 2jb4
        automatically matched to d1bk0a_
        complexed with a14, fe, gol, so4
        
        region a:3-331 [147954]
      6. 1qje
        Ip1 - Fe complex
        complexed with acv, fe2, ip1, so4
        
        chain a [28117]
      7. 1w04
        automatically matched to d1bk0__
        complexed with fe2, hcg, no, so4
        
        region a:3-331 [120557]
      8. 1bk0
        complexed with acv, fe, so4
        
        chain a [28118]
      9. 1uzw
        complexed with cdh, fe2, so4
        
        chain a [108183]
      10. 1hb2
        complexed with fe2, scv, so4
        
        chain a [65749]
      11. 1obn
        complexed with asv, fe2, nmo, so4
        
        chain a [92763]
      12. 1qjf
        monocyclic sulfoxide - Fe complex
        complexed with acs, fe2, so4
        
        chain a [28119]
      13. 2vbb
        automatically matched to d1bk0a_
        complexed with fe2, gol, so4, vaz
        
        region a:3-331 [152905]
      14. 1w3v
        automatically matched to d1bk0__
        complexed with fe2, mdz
        
        region a:3-331 [120624]
      15. 2ivj
        automatically matched to d1bk0__
        complexed with bcv, fe2, so4
        
        region a:3-331 [137724]
      16. 1hb3
        complexed with fe2, scv, so4
        
        chain a [65750]
      17. 1w3x
        automatically matched to d1bk0__
        complexed with fe2, w2x
        
        region a:3-331 [120625]
      18. 1blz
        complexed with acv, fe, no
        
        chain a [28120]
      19. 1qiq
        complexed with acc, fe, so4
        
        chain a [28121]
      20. 1hb4
        complexed with fe2, scv, so4
        
        chain a [65751]
      21. 1odn
        complexed with apv, fe2, so4
        
        chain a [86876]
      22. 1hb1
        complexed with fe2, ocv, so4
        
        chain a [65748]
      23. 1w06
        automatically matched to d1bk0__
        complexed with fe2, no, so4, w05
        
        region a:3-331 [120559]
      24. 2vau
        automatically matched to d1bk0a_
        complexed with fe2, v20
        
        region a:3-331 [152843]
      25. 2vbd
        automatically matched to d1bk0a_
        complexed with fe2, v10
        
        region a:3-331 [152906]
      26. 1w03
        automatically matched to d1bk0__
        complexed with fe2, hcg, so4
        
        region a:3-331 [120556]
      27. 1oc1
        complexed with asv, fe2, so4
        
        chain a [92764]
      28. 1w05
        automatically matched to d1bk0__
        complexed with fe2, so4, w05
        
        region a:3-331 [120558]
      29. 1ips
        complexed with mn
        
        chain a [28122]
        chain b [28123]
  2. Deacetoxycephalosporin C synthase [51201]
    1. Streptomyces clavuligerus [TaxId: 1901] [51202] (17)
      SQ P18548
      1. 1dcs
        complexed with so4
        
        chain a [28124]
      2. 1rxg
        complexed with akg, fe, so4
        
        chain a [28125]
      3. 1rxf
        complexed with fe
        
        chain a [28126]
      4. 1uo9
        complexed with fe2, sin
        
        chain a [99684]
      5. 1unb
        complexed with akg, fe2, pn1
        
        chain a [99673]
      6. 1hjg
        complexed with fe2, kiv; mutant
        
        chain a [61082]
      7. 2jb8
        automatically matched to d1dcsa_
        complexed with fe, hkv
        
        region a:1-308 [147961]
      8. 1uof
        complexed with fe2, pnn
        
        chain a [99688]
      9. 1hjf
        complexed with coi, fe2; mutant
        
        chain a [61081]
      10. 1uob
        complexed with akg, fe2, pnn
        
        chain a [99685]
      11. 1uog
        complexed with fe2, p1c
        
        chain a [99689]
      12. 1e5h
        complexed with co2, fe2, sin; mutant
        
        chain a [59269]
      13. 1w28
        
        chain a [114098]
      14. 1e5i
        complexed with akg, fe2; mutant
        
        chain a [59270]
      15. 1w2a
        complexed with edo, fe
        
        chain x [114099]
      16. 1w2n
        complexed with fe, pn1
        
        chain a [114100]
      17. 1w2o
        complexed with fe, p1c
        
        chain a [114101]
  3. Anthocyanidin synthase [69346]
    1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [69347] (4)
      1. 1gp6
        complexed with dh2, fe2, mes, que, sin
        
        chain a [65441]
      2. 1gp4
        complexed with 2og, mes
        
        chain a [65439]
      3. 1gp5
        complexed with 2og, dh2, dqh, fe, mes
        
        chain a [65440]
      4. 2brt
        automatically matched to d1gp6a_
        complexed with akg, fe2, nar
        
        region a:2-349 [129018]
  4. 1-aminocyclopropane-1-carboxylate oxidase 1 [141621]
    1. Petunia hybrida [TaxId: 4102] [141622] (2)
      SQ Q08506 2-308
      1. 1w9y
        complexed with so4
        
        region a:2-308 [120801]
      2. 1wa6
        automatically matched to 1W9Y A:2-308
        complexed with fe2, po4, so4
        
        region x:2-307 [120808]
2. Clavaminate synthase [51203] (1)
  1. Clavaminate synthase [51204]
    1. Streptomyces clavuligerus [TaxId: 1901] [51205] (5)
      1. 1ds1
        complexed with akg, fe2, pgo, so4
        
        chain a [28127]
      2. 1dry
        complexed with aag, akg, fe2, gol, so4
        
        chain a [28128]
      3. 1gvg
        complexed with akg, fe, nmo, pcx, so4
        
        chain a [76352]
      4. 1ds0
        complexed with act, so4
        
        chain a [28129]
      5. 1drt
        complexed with akg, fe2, pcv
        
        chain a [28130]
3. Gab protein (hypothetical protein YgaT) [63855] (1)
  1. Gab protein (hypothetical protein YgaT) [63856]
    unknown function
    1. Escherichia coli [TaxId: 562] [63857] (1)
      1. 1jr7
        complexed with fe2
        
        chain a [63255]
4. YhcH-like [89413] (1)
  1. Hypothetical protein HI0227 [89414]
    1. Haemophilus influenzae [TaxId: 727] [89415] (5)
      1. 1s4c
        automatically matched to d1jopa_
        complexed with act, cu
        
        region a:1-143 [118860]
      2. 1s4c
        automatically matched to d1jopa_
        complexed with act, cu
        
        region b:1-143 [118861]
      3. 1s4c
        automatically matched to d1jopa_
        complexed with act, cu
        
        region c:1-143 [118862]
      4. 1s4c
        automatically matched to d1jopa_
        complexed with act, cu
        
        region d:1-143 [118863]
      5. 1jop
        structural genomics
        complexed with hg
        
        chain a [84187]
        chain b [84188]
        chain c [84189]
        chain d [84190]
5. Type II Proline 3-hydroxylase (proline oxidase) [63858] (1)
  1. Type II Proline 3-hydroxylase (proline oxidase) [63859]
    1. Streptomyces sp. [TaxId: 1931] [63860] (2)
      1. 1e5r
        apo form
        
        chain a [59276]
        chain b [59277]
      2. 1e5s
        iron form
        complexed with fe2, so4
        
        chain a [59278]
        chain b [59279]
6. TauD/TfdA-like [75038] (2)
  1. Taurine/alpha-ketoglutarate dioxygenase TauD [75039]
    1. Escherichia coli [TaxId: 562] [75040] (4)
      1. 1otj
        complexed with cl, tau
        
        chain a [93517]
        chain b [93518]
        chain c [93519]
        chain d [93520]
      2. 1os7
        complexed with akg, fe2, tau
        
        chain a [93477]
        chain b [93478]
        chain c [93479]
        chain d [93480]
      3. 1gy9
        complexed with akg, fe, tau
        
        chain a [70742]
        chain b [70743]
      4. 1gqw
        complexed with akg, fe2, tau
        
        chain a [70377]
        chain b [70378]
  2. Putative alkylsulfatase AtsK [101989]
    1. Pseudomonas putida [TaxId: 303] [101990] (6)
      SQ Q9WWU5
      1. 1oih
        complexed with na
        
        chain a [93051]
        chain b [93052]
        chain c [93053]
        chain d [93054]
      2. 1oij
        complexed with akg, na
        
        chain a [93059]
        chain b [93060]
        chain c [93061]
        chain d [93062]
      3. 1oik
        complexed with akg, c26, fe2
        
        chain a [93063]
        chain d [93064]
      4. 1vz5
        complexed with sin
        
        chain a [114036]
        chain b [114037]
        chain c [114038]
        chain d [114039]
      5. 1oii
        complexed with akg, fe2
        
        chain a [93055]
        chain b [93056]
        chain c [93057]
        chain d [93058]
      6. 1vz4
        complexed with fe2, sin
        
        chain a [114034]
        chain d [114035]
7. gamma-Butyrobetaine hydroxylase [89416] (2)
  Pfam 03322
  1. Carbapenem synthase, CarC [89417]
    1. Erwinia carotovora [TaxId: 554] [89418] (2)
      1. 1nx4
        complexed with 2og, fe, mse
        
        chain a [86371]
        chain b [86372]
        chain c [86373]
      2. 1nx8
        complexed with 2og, fe, n7p
        
        chain a [86374]
        chain b [86375]
        chain c [86376]
  2. Clavaminate synthase-like protein At3g21360 [117321]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117322] (3)
      SQ Q9LIG0
      1. 1y0z
        Structural genomics target
        complexed with fe2, so4
        
        chain a [116317]
        chain b [116318]
      2. 2q4a
        automatically matched to d1y0zb_
        complexed with fe, so4
        
        region a:4-330 [139839]
      3. 2q4a
        automatically matched to d1y0zb_
        complexed with fe, so4
        
        region b:4-330 [139840]
8. Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1)
  1. Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195]
    1. Human (Homo sapiens) [TaxId: 9606] [82196] (10)
      1. 1h2k
        complex with HIF-1 alpha fragment peptide
        complexed with fe2, oga, so4
        
        chain a [76572]
      2. 1h2l
        complex with HIF-1 alpha fragment peptide
        complexed with akg, fe2, so4
        
        chain a [76574]
      3. 1mze
        complexed with fe2, tar
        
        chain a [79694]
      4. 1h2m
        complex with HIF-1 alpha fragment peptide
        complexed with oga, so4, zn
        
        chain a [76576]
      5. 1mzf
        complexed with akg, fe2
        
        chain a [79695]
      6. 2cgo
        automatically matched to d1mzea_
        complexed with fe, fmr, so4
        
        region a:13-349 [130427]
      7. 2cgn
        automatically matched to d1mzea_
        complexed with fe, sin, so4
        
        region a:13-349 [130426]
      8. 1h2n
        complexed with akg, fe2, so4
        
        chain a [76577]
      9. 1yci
        automatically matched to d1mzea_
        complexed with fe2, ndf, so4
        
        region a:14-349 [122965]
      10. 1iz3
        complexed with mse, so4
        
        chain a [83831]
9. PhyH-like [141623] (2)
  Pfam 05721
  1. Syringomycin biosynthesis enzyme 2, SyrB2 [141624]
    1. Pseudomonas syringae pv. syringae [TaxId: 321] [141625] (6)
      SQ Q9RBY6 3-310
      1. 2fct
        complexed with akg, cl, dsu, fe2
        
        region a:3-310 [133282]
      2. 2fct
        automatically matched to 2FCT A:3-310
        complexed with akg, cl, dsu, fe2
        
        region b:4-310 [133283]
      3. 2fcu
        automatically matched to 2FCT A:3-310
        complexed with akg, dsu
        
        region a:3-310 [133284]
      4. 2fcu
        automatically matched to 2FCT A:3-310
        complexed with akg, dsu
        
        region b:3-310 [133285]
      5. 2fcv
        automatically matched to 2FCT A:3-310
        complexed with akg, br, dsu, fe2
        
        region a:3-310 [133286]
      6. 2fcv
        automatically matched to 2FCT A:3-310
        complexed with akg, br, dsu, fe2
        
        region b:4-310 [133287]
  2. Phytanoyl-CoA dioxygenase, PhyH [141626]
    1. Human (Homo sapiens) [TaxId: 9606] [141627] (1)
      SQ O14832 43-338
      1. 2a1x
        complexed with akg, fe2
        
        region a:43-338 [126022]
10. AlkB-like [141628] (2)
  1. Alkylated DNA repair protein AlkB [141629]
    1. Escherichia coli [TaxId: 562] [141630] (7)
      SQ P05050 15-214
      1. 2fdi
        automatically matched to 2FD8 A:15-214
        complexed with akg, fe2, ma7, sin
        
        region a:15-214 [133311]
      2. 2fdj
        automatically matched to 2FD8 A:15-214
        complexed with fe2, sin
        
        region a:15-214 [133312]
      3. 2fdh
        automatically matched to 2FD8 A:15-214
        complexed with akg, ma7, mn
        
        region a:15-214 [133310]
      4. 2fdk
        automatically matched to 2FD8 A:15-214
        complexed with akg, fe2, ma7, sin
        
        region a:16-214 [133313]
      5. 2fdf
        automatically matched to 2FD8 A:15-214
        complexed with akg, co, ma7
        
        region a:15-214 [133308]
      6. 2fdg
        automatically matched to 2FD8 A:15-214
        complexed with fe2, ma7, sin
        
        region a:15-214 [133309]
      7. 2fd8
        complexed with akg, fe2, ma7
        
        region a:15-214 [133296]
  2. AlkB homolog 3 [141631]
    Prostate cancer antigen 1, DEPC-1
    1. Human (Homo sapiens) [TaxId: 9606] [141632] (1)
      SQ Q96Q83 70-279
      1. 2iuw
        complexed with akg, bme, fe, led
        
        region a:70-279 [137709]
11. Asparaginyl hydroxylase-like [141633] (1)
  Pfam 08007
  1. Putative asparaginyl hydroxylase YxbC [141634]
    1. Bacillus subtilis [TaxId: 1423] [141635] (4)
      SQ P46327 8-326
      1. 1vrb
        complexed with fe
        
        region a:8-326 [120450]
      2. 1vrb
        automatically matched to 1VRB A:8-326
        complexed with fe
        
        region b:8-326 [120451]
      3. 1vrb
        automatically matched to 1VRB A:8-326
        complexed with fe
        
        region c:8-326 [120452]
      4. 1vrb
        automatically matched to 1VRB A:8-326
        complexed with fe
        
        region d:8-326 [120453]
12. YbiU-like [141636] (1)
  Pfam 07350; DUF1479
  1. Hypothetical protein YbiU [141637]
    1. Salmonella typhimurium [TaxId: 90371] [141638] (1)
      SQ Q8ZQM7 3-419
      1. 2csg
        complexed with cit, fe, ict, sin
        
        region a:3-419 [130768]
13. TehB-like [159307] (2)
  Pfam 09313; DUF1971
  1. Uncharacterized protein YeaR [159308]
    1. Escherichia coli [TaxId: 562] [159309] (4)
      SQ P64488 1-109
      1. 3bb6
        complexed with zn
        
        region a:1-109 [155045]
      2. 3bb6
        automatically matched to 3BB6 A:1-109
        complexed with zn
        
        region b:1-109 [155046]
      3. 3bb6
        automatically matched to 3BB6 A:1-109
        complexed with zn
        
        region c:1-109 [155047]
      4. 3bb6
        automatically matched to 3BB6 A:1-109
        complexed with zn
        
        region d:1-103 [155048]
  2. Tellurite resistance protein B, TehB [159310]
    1. Vibrio fischeri [TaxId: 668] [159311] (8)
      SQ Q5E3X2 5-100
      1. 3dl3
        
        region a:5-100 [157762]
      2. 3dl3
        automatically matched to 3DL3 A:5-100
        
        region b:5-99 [157763]
      3. 3dl3
        automatically matched to 3DL3 A:5-100
        
        region d:5-99 [157764]
      4. 3dl3
        automatically matched to 3DL3 A:5-100
        
        region e:5-100 [157765]
      5. 3dl3
        automatically matched to 3DL3 A:5-100
        
        region f:5-100 [157766]
      6. 3dl3
        automatically matched to 3DL3 A:5-100
        
        region g:6-99 [157767]
      7. 3dl3
        automatically matched to 3DL3 A:5-100
        
        region h:5-99 [157768]
      8. 3dl3
        automatically matched to 3DL3 A:5-100
        
        region i:5-100 [157769]
cAMP-binding domain-like [51206] (3)
uperfamily
1. CO-sensing protein CooA, N-terminal domain [51207] (1)
  heme-binding domain
  1. CO-sensing protein CooA, N-terminal domain [51208]
    1. Rhodospirillum rubrum [TaxId: 1085] [51209] (1)
      1. 1ft9
        complexed with hem
        
        region a:2-133 [28131]
        region b:2-133 [28132]
2. Listeriolysin regulatory protein PrfA, N-terminal domain [89419] (1)
  1. Listeriolysin regulatory protein PrfA, N-terminal domain [89420]
    1. Bacteria (Listeria monocytogenes) [TaxId: 1639] [89421] (11)
      1. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region a:7-137 [128459]
      2. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region b:7-137 [128461]
      3. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region d:7-137 [128463]
      4. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region e:7-137 [128465]
      5. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region f:7-137 [128467]
      6. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region g:7-137 [128469]
      7. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region h:7-137 [128471]
      8. 2bgc
        automatically matched to d1omia1
        complexed with dtt, dtu; mutant
        
        region i:7-137 [128473]
      9. 2beo
        automatically matched to d1omia1
        complexed with acm, cl, gln, pg4
        
        region a:7-137 [128382]
      10. 2beo
        automatically matched to d1omia1
        complexed with acm, cl, gln, pg4
        
        region b:7-137 [128384]
      11. 1omi
        complexed with gol
        
        region a:1005-1137 [87079]
        region b:2005-2137 [87081]
3. cAMP-binding domain [51210] (14)
  Pfam 00027
  1. Catabolite gene activator protein, N-terminal domain [51211]
    1. Escherichia coli [TaxId: 562] [51212] (26)
      1. 1i5z
        complexed with cmp, trs
        
        region a:6-137 [83670]
        region b:1-137 [83672]
      2. 1zrf
        automatically matched to d1i5zb2
        complexed with cmp, dio
        
        region a:8-137 [125544]
      3. 1zrf
        automatically matched to d1i5zb2
        complexed with cmp, dio
        
        region b:8-137 [125546]
      4. 1g6n
        complexed with cmp
        
        region a:7-137 [28139]
        region b:307-437 [28140]
      5. 1hw5
        complexed with cmp; mutant
        
        region a:1-137 [28137]
        region b:1-137 [28138]
      6. 1i6x
        complexed with cmp, trs; mutant
        
        region a:6-137 [83674]
        region b:8-137 [83676]
      7. 2cgp
        protein/DNA complex; complexed with cmp
        
        region a:8-137 [28141]
      8. 2gzw
        automatically matched to d1i5zb2
        complexed with cmp
        
        region a:8-137 [135918]
      9. 2gzw
        automatically matched to d1i5zb2
        complexed with cmp
        
        region b:8-137 [135920]
      10. 2gzw
        automatically matched to d1i5zb2
        complexed with cmp
        
        region c:8-137 [135922]
      11. 2gzw
        automatically matched to d1i5zb2
        complexed with cmp
        
        region d:8-137 [135924]
      12. 1j59
        complexed with cmp
        
        region a:9-137 [71533]
        region b:9-137 [71535]
      13. 1zre
        automatically matched to d1i5zb2
        complexed with cmp
        
        region a:8-137 [125540]
      14. 1zre
        automatically matched to d1i5zb2
        complexed with cmp
        
        region b:8-137 [125542]
      15. 1zrc
        automatically matched to d1i5zb2
        complexed with cmp
        
        region a:8-137 [125532]
      16. 1zrc
        automatically matched to d1i5zb2
        complexed with cmp
        
        region b:8-137 [125534]
      17. 1zrd
        automatically matched to d1i5zb2
        complexed with cmp
        
        region a:8-137 [125536]
      18. 1zrd
        automatically matched to d1i5zb2
        complexed with cmp
        
        region b:8-137 [125538]
      19. 1o3r
        complexed with cmp
        
        region a:8-137 [86608]
      20. 1run
        protein/DNA complex; complexed with cmp
        
        region a:9-137 [28142]
        region b:9-137 [28143]
      21. 1lb2
        complexed with cmp
        
        region a:9-137 [77870]
      22. 1o3q
        complexed with cmp
        
        region a:8-137 [86606]
      23. 1o3s
        complexed with cmp; mutant
        
        region a:8-137 [86610]
      24. 1ruo
        protein/DNA complex; complexed with cmp; mutant
        
        region a:9-137 [28144]
        region b:9-137 [28145]
      25. 1cgp
        protein/DNA complex; complexed with cmp
        
        region a:9-137 [28135]
        region b:9-137 [28136]
      26. 1o3t
        complexed with cmp
        
        region a:9-137 [86612]
        region b:9-137 [86614]
  2. CRP-like transcriptional regulator TM1171, N-terminal domain [101991]
    1. Thermotoga maritima [TaxId: 2336] [101992] (1)
      1. 1o5l
        structural genomics
        DNA-binding domain (res. 130-213) is disordered in this structure
        
        region a:1-129 [92506]
  3. Regulatory subunit of Protein kinase A [51213]
    duplication: consists of two similar domains
    1. Cow (Bos taurus) [TaxId: 9913] [51214] (4)
      SQ P00514 109-376
      1. 1ne6
        complexed with sp1; mutant
        
        region a:109-244 [91831]
        region a:245-376 [91832]
      2. 1ne4
        complexed with rp1; mutant
        
        region a:109-244 [91829]
        region a:245-376 [91830]
      3. 1rl3
        complexed with gol, pcg
        
        region a:109-244 [104975]
        region a:245-376 [104976]
        region b:509-644 [104977]
        region b:645-767 [104978]
      4. 1rgs
        complexed with cmp; mutant
        
        region a:113-244 [28146]
        region a:245-376 [28147]
    2. Rat (Rattus norvegicus) [TaxId: 10116] [63861] (1)
      1. 1cx4
        complexed with cmp; mutant
        
        region a:130-265 [59099]
        region a:266-412 [59100]
  4. Regulatory domain of Epac2, domains 1 and 3 [82197]
    duplication: two homologous domains of this fold are separated in the sequence by a DEP domain
    1. Mouse (Mus musculus) [TaxId: 10090] [82198] (1)
      1. 1o7f
        
        region a:13-167 [81132]
        region a:322-445 [81133]
  5. HCN pacemaker channel [101993]
    potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel
    1. Mouse (Mus musculus) [TaxId: 10090] [101994] (5)
      1. 1q3e
        complexed with pcg
        
        chain a [95669]
        chain b [95670]
      2. 1q43
        complexed with cmp
        
        chain a [95777]
        chain b [95778]
      3. 1q5o
        complexed with cmp
        
        chain a [95902]
      4. 2q0a
        automatically matched to d1q5oa_
        complexed with pcg; mutant
        
        region a:443-635 [139781]
      5. 2q0a
        automatically matched to d1q5oa_
        complexed with pcg; mutant
        
        region b:443-635 [139782]
  6. Putative ion channel CnbD [110321]
    1. Mesorhizobium loti [TaxId: 381] [110322] (4)
      SQ Q98GN8 218-350 # mll3241
      1. 1vp6
        complexed with br, cmp
        
        chain a [113939]
        chain c [113940]
      2. 3cl1
        automatically matched to d1vp6a_
        complexed with cl, k, pcg, pol
        
        region a:220-349 [156750]
      3. 3cl1
        automatically matched to d1vp6a_
        complexed with cl, k, pcg, pol
        
        region b:220-349 [156751]
      4. 1u12
        complexed with iod, k, so4; mutant
        
        chain a [112946]
        chain b [112947]
  7. Probable cyclic nucleotide-gated ion channel 6 [117323]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117324] (1)
      SQ O82226 509-632
      1. 1wgp
        Structural genomics target
        
        chain a [114619]
  8. Probable transcription regulator BT4300, N-terminal domain [141639]
    1. Bacteroides thetaiotaomicron [TaxId: 818] [141640] (1)
      SQ Q89ZS6 1-147
      1. 1zyb
        complexed with gol
        
        region a:1-147 [125816]
  9. Transcriptional regulator TTHA1359, N-terminal domain [141641]
    1. Thermus thermophilus [TaxId: 274] [141642] (1)
      SQ Q5SIL0 6-117
      1. 2coh
        complexed with mpd
        
        region a:6-117 [130678]
  10. Transcriptional regulator PG0396, N-terminal domain [141643]
    1. Porphyromonas gingivalis [TaxId: 837] [141644] (1)
      SQ Q7MAW7 10-151
      1. 2gau
        
        region a:10-151 [134895]
  11. Cyclic AMP receptor-like protein Vfr [159312]
    1. Pseudomonas aeruginosa [TaxId: 287] [159313] (1)
      SQ P55222 9-142
      1. 2oz6
        complexed with cmp
        
        region a:9-142 [149104]
  12. Chlorophenol reduction protein CprK [159314]
    1. Desulfitobacterium hafniense [TaxId: 49338] [159315] (7)
      SQ Q18R04 3-147! SQ Q18R04 9-147
      1. 3e5u
        complexed with 3c4, na, po4; mutant
        
        region a:9-147 [158023]
      2. 3e5u
        automatically matched to 3E5U A:9-147
        complexed with 3c4, na, po4; mutant
        
        region b:9-147 [158025]
      3. 3e5u
        automatically matched to 3E5U A:9-147
        complexed with 3c4, na, po4; mutant
        
        region c:9-147 [158027]
      4. 3e5u
        automatically matched to 3E5U A:9-147
        complexed with 3c4, na, po4; mutant
        
        region d:9-147 [158029]
      5. 3e6c
        automatically matched to 3E5U A:9-147
        complexed with 3c4; mutant
        
        region c:9-147 [158039]
      6. 2h6b
        complexed with 3c4, so4
        
        region a:3-147 [147229]
      7. 2h6b
        automatically matched to 2H6B A:3-147
        complexed with 3c4, so4
        
        region b:9-147 [147231]
    2. Desulfitobacterium dehalogenans [TaxId: 36854] [159316] (2)
      SQ Q9LAS2 19-147
      1. 2h6c
        
        region a:19-147 [147233]
      2. 2h6c
        automatically matched to 2H6C A:19-147
        
        region b:19-147 [147235]
Regulatory protein AraC [51215] (1)
uperfamily
1. Regulatory protein AraC [51216] (1)
  1. Regulatory protein AraC [51217]
    contains an alpha-hairpin in the C-terminal extension
    1. Escherichia coli [TaxId: 562] [51218] (4)
      SQ P03021
      1. 2arc
        complexed with ara
        
        chain a [28148]
        chain b [28149]
      2. 2aac
        complexed with acy, fcb
        
        chain a [28150]
        chain b [28151]
      3. 1xja
        complexed with edo; mutant
        
        chain a [115382]
        chain b [115383]
        chain c [115384]
        chain d [115385]
        chain e [115386]
      4. 2ara
        
        chain a [28152]
Thiamin pyrophosphokinase, substrate-binding domain [63862] (1)
uperfamily
1. Thiamin pyrophosphokinase, substrate-binding domain [63863] (2)
  1. Thiamin pyrophosphokinase, substrate-binding domain [63864]
    1. Mouse (Mus musculus) [TaxId: 10090] [63865] (2)
      1. 1ig3
        complexed with so4, vib
        
        region a:179-263 [62358]
        region b:179-263 [62360]
      2. 2f17
        automatically matched to d1ig3a1
        complexed with amp, epe, mg, pyi, so4
        
        region a:159-243 [132717]
    2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [63866] (1)
      1. 1ig0
        complexed with vib
        
        region a:224-319 [62354]
        region b:224-319 [62356]
Calcium ATPase, transduction domain A [81653] (1)
a distorted variant of double-helix
uperfamily
1. Calcium ATPase, transduction domain A [81652] (1)
  1. Calcium ATPase, transduction domain A [81651]
    1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [81650] (17)
      SQ P04191
      1. 1wpg
        complexed with adp, mf4, mg, na, tg1
        
        region a:125-239 [114806]
        region b:125-239 [114810]
        region c:125-239 [114814]
        region d:125-239 [114818]
      2. 2zbf
        automatically matched to d1iwoa1
        complexed with ace, bef, mg, tg1
        
        region a:125-239 [154313]
      3. 2zbd
        automatically matched to d1iwoa1
        complexed with ace, adp, alf, ca, mg, pc1
        
        region a:125-239 [154301]
      4. 2zbg
        automatically matched to d1iwoa1
        complexed with ace, alf, mg, tg1
        
        region a:125-239 [154317]
      5. 1su4
        complexed with ca, na
        
        region a:125-239 [98993]
      6. 1t5s
        complexed with acp, ca, k, mg
        
        region a:125-239 [106473]
      7. 3b9b
        automatically matched to d1iwoa1
        complexed with bef, mg, na
        
        region a:125-239 [154994]
      8. 1vfp
        complexed with acp, ca, mg
        
        region a:125-239 [108576]
        region b:125-239 [108580]
      9. 1t5t
        complexed with adp, alf, ca, k, mg
        
        region a:125-239 [106477]
      10. 3b9r
        automatically matched to d1iwoa1
        complexed with acp, alf, k, mg
        
        region a:125-239 [155014]
      11. 3b9r
        automatically matched to d1iwoa1
        complexed with acp, alf, k, mg
        
        region b:125-239 [155018]
      12. 1xp5
        complexed with alf, k, mg, tg1
        
        region a:125-239 [115730]
      13. 1wpe
        complexed with adp, af3, ca, mg
        
        region a:125-239 [114802]
      14. 1iwo
        Structure in the absence of calcium ions
        complexed with tg1
        
        region a:125-239 [75854]
        region b:125-239 [75858]
      15. 2zbe
        automatically matched to d1iwoa1
        complexed with ace, bef, mg
        
        region a:125-239 [154305]
      16. 2zbe
        automatically matched to d1iwoa1
        complexed with ace, bef, mg
        
        region b:125-239 [154309]
      17. 1kju
        Structure in the e2 state
        
        region a:125-239 [75892]
TRAP-like [51219] (2)
shorter variant of double-helix; assembles in large ring-like structures containing from 9 to 11 domains
uperfamily
1. Trp RNA-binding attenuation protein (TRAP) [51220] (2)
  oligomeric ring consists of 11 single-domain subunits
  1. Trp RNA-binding attenuation protein (TRAP) [51221]
    1. Bacillus subtilis [TaxId: 1423] [51222] (1)
      1. 1wap
        
        chain a [28153]
        chain b [28154]
        chain c [28155]
        chain d [28156]
        chain e [28157]
        chain f [28158]
        chain g [28159]
        chain h [28160]
        chain i [28161]
        chain j [28162]
        chain k [28163]
        chain l [28164]
        chain m [28165]
        chain n [28166]
        chain o [28167]
        chain p [28168]
        chain q [28169]
        chain r [28170]
        chain s [28171]
        chain t [28172]
        chain u [28173]
        chain v [28174]
    2. Bacillus stearothermophilus [TaxId: 1422] [51223] (19)
      1. 1gtf
        complexed with trp
        
        chain a [70460]
        chain b [70461]
        chain c [70462]
        chain d [70463]
        chain e [70464]
        chain f [70465]
        chain g [70466]
        chain h [70467]
        chain i [70468]
        chain j [70469]
        chain k [70470]
        chain l [70471]
        chain m [70472]
        chain n [70473]
        chain o [70474]
        chain p [70475]
        chain q [70476]
        chain r [70477]
        chain s [70478]
        chain t [70479]
        chain u [70480]
        chain v [70481]
      2. 2ext
        automatically matched to d1c9sm_
        complexed with trp
        
        region a:7-69 [132563]
      3. 2ext
        automatically matched to d1c9sm_
        complexed with trp
        
        region b:7-69 [132564]
      4. 2ext
        automatically matched to d1c9sm_
        complexed with trp
        
        region c:7-69 [132565]
      5. 2zcz
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region a:7-75 [154379]
      6. 2zcz
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region b:7-73 [154380]
      7. 2zcz
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region c:7-72 [154381]
      8. 2zcz
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region d:7-75 [154382]
      9. 2zcz
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region e:7-74 [154383]
      10. 2zcz
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region f:7-72 [154384]
      11. 1c9s
        protein/RNA complex
        
        chain a [28175]
        chain b [28176]
        chain c [28177]
        chain d [28178]
        chain e [28179]
        chain f [28180]
        chain g [28181]
        chain h [28182]
        chain i [28183]
        chain j [28184]
        chain k [28185]
        chain l [28186]
        chain m [28187]
        chain n [28188]
        chain o [28189]
        chain p [28190]
        chain q [28191]
        chain r [28192]
        chain s [28193]
        chain t [28194]
        chain u [28195]
        chain v [28196]
      12. 1utv
        complexed with trp
        
        chain a [99971]
        chain b [99972]
        chain c [99973]
        chain d [99974]
        chain e [99975]
        chain f [99976]
        chain g [99977]
        chain h [99978]
        chain i [99979]
        chain j [99980]
        chain k [99981]
        chain l [99982]
        chain m [99983]
        chain n [99984]
        chain o [99985]
        chain p [99986]
        chain q [99987]
        chain r [99988]
        chain s [99989]
        chain t [99990]
        chain u [99991]
        chain v [99992]
      13. 1utf
        complexed with trp
        
        chain a [99940]
        chain b [99941]
        chain c [99942]
        chain d [99943]
        chain e [99944]
        chain f [99945]
        chain g [99946]
        chain h [99947]
        chain i [99948]
        chain j [99949]
        chain k [99950]
        chain l [99951]
        chain m [99952]
        chain n [99953]
        chain o [99954]
        chain p [99955]
        chain q [99956]
        chain r [99957]
        chain s [99958]
        chain t [99959]
        chain u [99960]
        chain v [99961]
      14. 1utd
        complexed with trp
        
        chain a [99918]
        chain b [99919]
        chain c [99920]
        chain d [99921]
        chain e [99922]
        chain f [99923]
        chain g [99924]
        chain h [99925]
        chain i [99926]
        chain j [99927]
        chain k [99928]
        chain l [99929]
        chain m [99930]
        chain n [99931]
        chain o [99932]
        chain p [99933]
        chain q [99934]
        chain r [99935]
        chain s [99936]
        chain t [99937]
        chain u [99938]
        chain v [99939]
      15. 2zd0
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region a:7-69 [154385]
      16. 2zd0
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region b:7-72 [154386]
      17. 2zd0
        automatically matched to d1c9sm_
        complexed with trp; mutant
        
        region c:7-72 [154387]
      18. 1gtn
        complexed with trp
        
        chain a [70507]
        chain b [70508]
        chain c [70509]
        chain d [70510]
        chain e [70511]
        chain f [70512]
        chain g [70513]
        chain h [70514]
        chain i [70515]
        chain j [70516]
        chain k [70517]
        chain l [70518]
        chain m [70519]
        chain n [70520]
        chain o [70521]
        chain p [70522]
        chain q [70523]
        chain r [70524]
        chain s [70525]
        chain t [70526]
        chain u [70527]
        chain v [70528]
      19. 1qaw
        
        chain a [28197]
        chain b [28198]
        chain c [28199]
        chain d [28200]
        chain e [28201]
        chain f [28202]
        chain g [28203]
        chain h [28204]
        chain i [28205]
        chain j [28206]
        chain k [28207]
2. PA3696/SPS0176-like [101995] (2)
  duplication: there are three structural repeats per subunit; nine domains per ring-like trimer
  1. Hypothetical protein SPyM3_0169 (SPyM18_0222, SPS0176) [101996]
    1. Streptococcus pyogenes [TaxId: 1314] [101997] (1)
      1. 1pg6
        structural genomics; NESG target DR2
        complexed with ca
        
        chain a [94673]
  2. Hypothetical protein PA3696 [141645]
    1. Pseudomonas aeruginosa [TaxId: 287] [141646] (6)
      SQ Q9HXU4 5-244
      1. 1yox
        
        region a:5-244 [123789]
      2. 1yox
        automatically matched to 1YOX A:5-244
        
        region b:5-237 [123790]
      3. 1yox
        automatically matched to 1YOX A:5-244
        
        region c:5-237 [123791]
      4. 1yox
        automatically matched to 1YOX A:5-244
        
        region d:5-237 [123792]
      5. 1yox
        automatically matched to 1YOX A:5-244
        
        region e:5-237 [123793]
      6. 1yox
        automatically matched to 1YOX A:5-244
        
        region f:5-242 [123794]