Superfamily: Methionyl-tRNA synthetase (MetRS), Zn-domain

uperfamily

Lineage:

1. Root: scop
2. Class: Small proteins [56992]
   Usually dominated by metal ligand, heme, and/or disulfide bridges
3. Fold: Rubredoxin-like [57769]
   metal(zinc or iron)-bound fold; sequence contains two CX(n)C motifs, in most cases n = 2
4. Superfamily: Methionyl-tRNA synthetase (MetRS), Zn-domain [57770]
   uperfamily

Families:

1. Methionyl-tRNA synthetase (MetRS), Zn-domain [57771] (2)
   in the Pyrococcus abyssi MetRS structure there is a tandem repeat of two such domains swapped with their zinc-binding 'knuckles', this duplicated finger occupies a larger region (124-183) than defined below; there is a structurally equivalent region in the E. coli enzyme lacking the second zinc-binding site
   1. Methionyl-tRNA synthetase (MetRS), Zn-domain [57772]
      1. Escherichia coli [TaxId: 562] [57773] (9)
         1. 1pfv
            complexed with 2fm, zn
            1. region a:141-175 [94662]
         2. 1pfw
            complexed with mf3, zn
            1. region a:141-175 [94665]
         3. 1p7p
            complexed with mph, zn
            1. region a:141-175 [94311]
         4. 1f4l
            complexed with met, zn
            1. region a:141-175 [59650]
         5. 1pfu
            complexed with mpj, zn
            1. region a:141-175 [94659]
         6. 1pfy
            complexed with msp, zn
            1. region a:141-175 [94668]
         7. 1qqt
            1. region a:141-175 [45175]
         8. 1mea
            complexed with zn
            1. chain a [45176]
         9. 1med
            complexed with zn
            1. chain a [45177]
      2. Pyrococcus abyssi [TaxId: 29292] [111451] (1)
         SQ Q9V011 1-606; C-domain 616-722 is solved separately: 1MKH
         1. 1rqg
            complexed with zn
            1. region a:139-173 [105065]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk