Structural Classification of Proteins
home mail help root up expand collapse

Family: HkH motif-containing C2H2 finger

putative dsRNA-specific zinc finger with a helix-kink-helix (HkH) motif; the kink results from the incompatibility of the cation-coordinating H-x5-H motif with a regular alpha-helix and contributes to RNA recognition

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: beta-beta-alpha zinc fingers [57666]
    simple fold, consisting of the N-terminal beta-hairpin and C-terminal alpha-helical region; each part provides two zinc-coordinating residues with the observed sequences including C2H2, C2HC and CHHC
  4. Superfamily: beta-beta-alpha zinc fingers [57667]
    link to SUPERFAMILY database - Superfamily
  5. Family: HkH motif-containing C2H2 finger [111436]
    putative dsRNA-specific zinc finger with a helix-kink-helix (HkH) motif; the kink results from the incompatibility of the cation-coordinating H-x5-H motif with a regular alpha-helix and contributes to RNA recognition

Protein Domains:

  1. Spliceosomal protein U1C [111437]
    1. Human (Homo sapiens) [TaxId: 9606] [111438] (1) picpic
      SQ P09234 1-61
  2. Zinc finger protein 593, ZNF593 [144151]
    1. Human (Homo sapiens) [TaxId: 9606] [144152] (1) picpic
      SQ O00488 28-94
  3. dsRNA-binding protein ZFa (ZNF346, JAZ) [161154]
    1. African clawed frog (Xenopus laevis) [TaxId: 8355] [161155] (2) picpic
      SQ Q8AVN9 2-73!SQ Q8AVN9 74-128
  4. Zinc finger homeobox protein 4, ZFHX4 [161156]
    1. Human (Homo sapiens) [TaxId: 9606] [161157] (1) picpic
      SQ Q9JJN9 2937-2984

Enter search key:

MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk