Fold: beta-beta-alpha zinc fingers

simple fold, consisting of the N-terminal beta-hairpin and C-terminal alpha-helical region; each part provides two zinc-coordinating residues with the observed sequences including C2H2, C2HC and CHHC

Lineage:

1. Root: scop
2. Class: Small proteins [56992]
   Usually dominated by metal ligand, heme, and/or disulfide bridges
3. Fold: beta-beta-alpha zinc fingers [57666]
   simple fold, consisting of the N-terminal beta-hairpin and C-terminal alpha-helical region; each part provides two zinc-coordinating residues with the observed sequences including C2H2, C2HC and CHHC

Superfamilies:

1. beta-beta-alpha zinc fingers [57667] (7)
   uperfamily
   1. Classic zinc finger, C2H2 [57668] (30)
   2. Plant C2H2 finger (QALGGH zinc finger) [90198] (1)
   3. C2HC finger [57697] (3)
   4. HkH motif-containing C2H2 finger [111436] (4)
      putative dsRNA-specific zinc finger with a helix-kink-helix (HkH) motif; the kink results from the incompatibility of the cation-coordinating H-x5-H motif with a regular alpha-helix and contributes to RNA recognition
   5. CHHC finger [161158] (1)
   6. variant C2H2 finger [118273] (1)
      contains extra C-terminal, alpha-helical subdomain
   7. BED zinc finger [144157] (1)
      Pfam 02892; contains extra N-terminal and C-terminal helices bundled together with the core helix

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk