Structural Classification of Proteins
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Family: Bcl-2 inhibitors of programmed cell death

Pfam 00452

Lineage:

  1. Root: scop
  2. Class: Membrane and cell surface proteins and peptides [56835]
    Does not include proteins in the immune system
  3. Fold: Toxins' membrane translocation domains [56836]
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. Superfamily: Bcl-2 inhibitors of programmed cell death [56854]
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
    link to SUPERFAMILY database - Superfamily
  5. Family: Bcl-2 inhibitors of programmed cell death [56855]
    Pfam 00452

Protein Domains:

  1. Bcl-2 [64524]
    1. Human (Homo sapiens) [TaxId: 9606] [64525] (5) picpic
  2. Apoptosis regulator Bcl-xL [56856]
    1. Human (Homo sapiens) [TaxId: 9606] [56857] (15) picpic
    2. Mouse (Mus musculus) [TaxId: 10090] [103423] (3) picpic
    3. Rat (Rattus norvegicus) [TaxId: 10116] [56858] (1) picpic
  3. Apoptosis regulator Bcl-w [90103]
    1. Human (Homo sapiens) [TaxId: 9606] [90104] (3) picpic
  4. Proapoptotic molecule Bid [56859]
    1. Human (Homo sapiens) [TaxId: 9606] [56860] (1) picpic
    2. Mouse (Mus musculus) [TaxId: 10090] [56861] (1) picpic
  5. Proapoptotic molecule Bax [56862]
    1. Human (Homo sapiens) [TaxId: 9606] [56863] (2) picpic
  6. Bcl-2 homolog [75637]
    1. Kaposi's sarcoma-associated herpesvirus [TaxId: 37296] [75638] (1) picpic
  7. Apoptosis regulator ced-9 [103424]
    1. Nematode (Caenorhabditis elegans) [TaxId: 6239] [103425] (3) picpic
      SQ P41958 74-237
  8. Early antigen protein R [103426]
    1. Epstein-Barr virus [TaxId: 10376] [103427] (1) picpic
  9. EAT/MCL-1 (Myeloid cell leukemia sequence 1) [118212]
    1. Mouse (Mus musculus) [TaxId: 10090] [118213] (4) picpic
      SQ P97287 152-308
  10. Bcl-2 homolog V-bcl-2 [144081]
    1. Murid herpesvirus 4 [TaxId: 33708] [144082] (5) picpic
      SQ P89884 6-136
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk