Structural Classification of Proteins
home mail help root up expand collapse

Protein: Nsp15, C-terminal domain from Murine hepatitis virus, MHV [TaxId: 11138]

SQ P16342 6720-6872

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: EndoU-like [142876]
    comprises several helices and two three-stranded antiparallel beta-sheets; similar architecture to the RNase A-like fold (scop_cf 54075)
  4. Superfamily: EndoU-like [142877]
    similarity to the RNase A-like superfamily (scop_sf 54076) extends to the active site location and architecture; the two structural cores of the RNase A and EndoU superfamilies are interrelated by a topological permutation - transposition of two pereferial beta-strands, suggesting possible distant homology of the two superfamilies (and their unification in a hyperfamily)
    link to SUPERFAMILY database - Superfamily
  5. Family: Nsp15 C-terminal domain-like [142881]
    PfamB 001946
  6. Protein: Nsp15, C-terminal domain [142882]
  7. Species: Murine hepatitis virus, MHV [TaxId: 11138] [142884]
    SQ P16342 6720-6872

PDB Entry Domains:

  1. 2gti picpicxref
    complexed with gol, so4; mutant
    1. region a:217-369 [135653] picpiclink
  2. 2gth picpicxref
    1. region a:217-369 [135651] picpiclink
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk