Structural Classification of Proteins
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Family: ADP-ribosylating toxins

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: ADP-ribosylation [56398]
    unusual fold
  4. Superfamily: ADP-ribosylation [56399]
    link to SUPERFAMILY database - Superfamily
  5. Family: ADP-ribosylating toxins [56400]

Protein Domains:

  1. Heat-labile toxin, A-chain [56401]
    1. Escherichia coli, type IB [TaxId: 562] [56402] (9) picpic
    2. Escherichia coli, type IIB [TaxId: 562] [56403] (1) picpic
  2. Diphtheria toxin, N-terminal domain [56404]
    1. Corynebacterium diphtheriae [TaxId: 1717] [56405] (7) picpic
  3. Exotoxin A, C-terminal domain [56406]
    1. Pseudomonas aeruginosa [TaxId: 287] [56407] (21) picpic
  4. Pertussis toxin, S1 subunit [56408]
    1. Bordetella pertussis [TaxId: 520] [56409] (3) picpic
  5. Cholera toxin [56410]
    1. Vibrio cholerae [TaxId: 666] [56411] (9) picpic
  6. Vegetative insecticidal protein 2 (VIP2) [56412]
    duplication: consists of two domains of this fold, the second of which is catalytic
    1. Bacillus cereus [TaxId: 1396] [56413] (2) picpic
  7. Enzymatic component (Ia) of iota-toxin [82812]
    mammalian-targeted relative of VIP2; C-terminal domain is catalytic, N-terminal domain interacts with Ib (binding component)
    1. Clostridium perfringens [TaxId: 1502] [82813] (4) picpic
  8. Exoenzyme c3 [56414]
    1. Clostridium botulinum [TaxId: 1491] [56415] (14) picpic
      SQ P15879 41-251
    2. Staphylococcus aureus [TaxId: 1280] [103338] (2) picpic
    3. Clostridium botulinum C bacteriophage [TaxId: 12336] [118161] (2) picpic
      SQ Q00901 44-244
  9. Anthrax toxin lethal factor, middle domain [69845]
    includes an all-alpha insert subdomain
    1. Bacillus anthracis [TaxId: 1392] [69846] (10) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk