Structural Classification of Proteins
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Family: Lactate & malate dehydrogenases, C-terminal domain

N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: LDH C-terminal domain-like [56326]
    unusual fold, defines family
  4. Superfamily: LDH C-terminal domain-like [56327]
    link to SUPERFAMILY database - Superfamily
  5. Family: Lactate & malate dehydrogenases, C-terminal domain [56328]
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)

Protein Domains:

  1. Malate dehydrogenase [56329]
    1. Pig (Sus scrofa) [TaxId: 9823] [56330] (3) picpic
    2. Sorghum (Sorghum vulgare), chloroplast [TaxId: 4558] [56331] (1) picpic
    3. Flaveria bidentis, chloroplast [TaxId: 4224] [56332] (1) picpic
    4. Escherichia coli [TaxId: 562] [56333] (8) picpic
    5. Thermus flavus [TaxId: 274] [56334] (2) picpic
    6. Thermus thermophilus [TaxId: 274] [82806] (9) picpic
      identical sequence to that from the Thermus flavus enzyme
    7. Archaeon Haloarcula marismortui [TaxId: 2238] [56335] (17) picpic
    8. Aquaspirillum arcticum [TaxId: 87645] [56336] (3) picpic
    9. Chloroflexus aurantiacus [TaxId: 1108] [69840] (7) picpic
      SQ P80040
    10. Chlorobium tepidum [TaxId: 1097] [69841] (1) picpic
    11. Chlorobium vibrioforme [TaxId: 1098] [69842] (2) picpic
  2. L-2-hydroxyisocapronate dehydrogenase, L-HICDH [56337]
    1. Lactobacillus confusus [TaxId: 1583] [56338] (1) picpic
  3. Lactate dehydrogenase [56339]
    1. Pig (Sus scrofa) [TaxId: 9823] [56340] (3) picpic
    2. Human (Homo sapiens), heart isoform (H chain) [TaxId: 9606] [64444] (2) picpic
    3. Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606] [64445] (1) picpic
    4. Mouse (Mus musculus) [TaxId: 10090] [56341] (4) picpic
    5. Dogfish (Squalus acanthias) [TaxId: 7797] [56342] (3) picpic
    6. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [56343] (9) picpic
    7. Plasmodium berghei [TaxId: 5821] [103325] (7) picpic
    8. Toxoplasma gondii [TaxId: 5811] [103326] (4) picpic
    9. Bacillus stearothermophilus [TaxId: 1422] [56344] (9) picpic
    10. Lactobacillus casei [TaxId: 1582] [56345] (1) picpic
    11. Lactobacillus pentosus [TaxId: 1589] [69843] (1) picpic
    12. Bifidobacterium longum, strain am101-2 [TaxId: 216816] [56346] (2) picpic
    13. Thermotoga maritima [TaxId: 2336] [56347] (1) picpic
    14. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [111253] (2) picpic
      SQ O08349
    15. Clostridium thermocellum [TaxId: 1515] [118160] (1) picpic
      SQ Q4CDK5
  4. MJ0490, lactate/malate dehydrogenase [64446]
    1. Archaeon Methanococcus jannaschii [TaxId: 2190] [64447] (2) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk