Fold: Hect, E3 ligase catalytic domain

consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: Hect, E3 ligase catalytic domain [56203]
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

Superfamilies:

1. Hect, E3 ligase catalytic domain [56204] (1)
   uperfamily
   1. Hect, E3 ligase catalytic domain [56205] (2)
      1. Ubiquitin-protein ligase E3a (E6ap) [56206]
         1. Human (Homo sapiens) [TaxId: 9606] [56207] (2)
      2. WW domain-containing protein 1, WWP1 [103308]
         1. Human (Homo sapiens) [TaxId: 9606] [103309] (1)

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk