Structural Classification of Proteins
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Family: Transglutaminase core

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Cysteine proteinases [54000]
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. Superfamily: Cysteine proteinases [54001]
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
    link to SUPERFAMILY database - Superfamily
  5. Family: Transglutaminase core [54044]

Protein Domains:

  1. Transglutaminase catalytic domain [54045]
    1. Human (Homo sapiens), blood isozyme [TaxId: 9606] [54046] (8)
      Coagulation factor XIII
      1. 1ex0 picpicxrefxref
        complexed with ca, pgo, po4; mutant
        1. region a:191-510 [90468] picpiclink
        2. region b:191-511 [90472] picpiclink
      2. 1f13 picpicxrefxref
        1. region a:191-515 [37107] picpiclink
        2. region b:191-515 [37108] picpiclink
      3. 1evu picpicxrefxref
        complexed with ca, pgo
        1. region a:191-508 [37113] picpiclink
        2. region b:191-508 [37114] picpiclink
      4. 1ggu picpicxrefxref
        complexed with ca
        1. region a:191-508 [37115] picpiclink
        2. region b:191-508 [37116] picpiclink
      5. 1fie picpicxrefxref
        1. region a:191-515 [37109] picpiclink
        2. region b:191-515 [37110] picpiclink
      6. 1qrk picpicxrefxref
        complexed with sr
        1. region a:191-511 [37119] picpiclink
        2. region b:191-507 [37120] picpiclink
      7. 1ggy picpicxrefxref
        complexed with yb
        1. region a:191-508 [37117] picpiclink
        2. region b:191-508 [37118] picpiclink
      8. 1ggt picpicxrefxref
        1. region a:191-515 [37111] picpiclink
        2. region b:191-515 [37112] picpiclink
    2. Human (Homo sapiens), tissue isozyme [TaxId: 9606] [75333] (2)
      GDP-binding protein
      1. 2q3z picpicxrefxrefxref
        automatically matched to d1kv3a4
        complexed with ace, nh2, onl, so4
        1. region a:146-461 [150040] picpiclink
      2. 1kv3 picpicxrefxref
        complexed with gdp
        1. region a:146-468 [73030] picpiclink
        2. region b:146-468 [73034] picpiclink
        3. region c:146-468 [73038] picpiclink
        4. region d:146-468 [73042] picpiclink
        5. region e:146-468 [73046] picpiclink
        6. region f:146-468 [73050] picpiclink
    3. Human (Homo sapiens), TGase E3 [TaxId: 9606] [75334] (8)
      1. 1vjj picpicxrefxref
        complexed with ca, cl, gdp, mg; mutant
        1. region a:141-461 [100817] picpiclink
        2. region b:141-459 [100821] picpiclink
      2. 1sgx picpicxrefxref
        complexed with 5gp, ca, mg; mutant
        1. region a:141-461 [98865] picpiclink
        2. region b:141-459 [98869] picpiclink
      3. 1l9n picpicxrefxref
        complexed with bgl, ca, cl; mutant
        1. region a:141-460 [73743] picpiclink
        2. region b:141-460 [73747] picpiclink
      4. 1rle picpicxrefxref
        complexed with ca, gsp, mg; mutant
        1. region a:141-461 [97641] picpiclink
        2. region b:141-459 [97645] picpiclink
      5. 1l9m picpicxrefxref
        complexed with br, ca, cl; mutant
        1. region a:141-461 [73735] picpiclink
        2. region b:141-460 [73739] picpiclink
      6. 1nug picpicxrefxref
        complexed with ca, cl, mg; mutant
        1. region a:141-461 [86189] picpiclink
        2. region b:141-459 [86193] picpiclink
      7. 1nuf picpicxrefxref
        complexed with br, ca, cl; mutant
        1. region a:141-461 [86185] picpiclink
      8. 1nud picpicxrefxref
        complexed with br, ca, cl; mutant
        1. region a:141-460 [86177] picpiclink
        2. region b:141-460 [86181] picpiclink
    4. Red sea bream (Chrysophrys major) [TaxId: 143350] [64204] (1)
      1. 1g0d picpicxrefxref
        complexed with so4
        1. region a:141-461 [60169] picpiclink
  2. Peptide:N-glycanase 1, PNG1 [142852]
    1. Baker's yeast(Saccharomyces cerevisiae) [TaxId: 4932] [142853] (2)
      SQ Q02890 8-327
      1. 1x3z picpicxref
        automatically matched to 1X3W A:8-327
        complexed with suc, zn
        1. region a:8-327 [121673] picpiclink
      2. 1x3w picpicxref
        complexed with suc, zn
        1. region a:8-327 [121671] picpiclink
    2. Mouse (Mus musculus) [TaxId: 10090] [159840] (2)
      SQ Q9JI78 164-450
      1. 2f4m picpicxref
        complexed with cl, zn
        1. region a:164-450 [145135] picpiclink
      2. 2f4o picpicxref
        automatically matched to 2F4M A:164-450
        complexed with cl, phq, zn
        1. region a:164-447 [145136] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk