Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain

has a circularly permuted topology
uperfamily

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: ATP-grasp [56058]
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies
4. Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain [56091]
   has a circularly permuted topology
   uperfamily

Families:

1. ATP-dependent DNA ligase catalytic domain [56092] (3)
   1. ATP-dependent DNA ligase, N-terminal domain [56093]
      1. Bacteriophage T7 [TaxId: 10760] [56094] (1)
      2. Chlorella virus PBCV-1 [TaxId: 10506] [56095] (7)
   2. DNA ligase I (LIG1) [118122]
      1. Human (Homo sapiens) [TaxId: 9606] [118123] (1)
         SQ P18858 262-901
2. Adenylation domain of NAD+-dependent DNA ligase [56096] (3)
   1. Adenylation domain of NAD+-dependent DNA ligase [56097]
      contains additional, N-terminal all-alpha subdomain
      1. Bacillus stearothermophilus [TaxId: 1422] [56098] (1)
      2. Thermus filiformis [TaxId: 276] [56099] (2)
      3. Enterococcus faecalis [TaxId: 1351] [118124] (2)
         SQ Q837V6 5-317
3. mRNA capping enzyme [56100] (2)
   1. RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain [56101]
      1. Chlorella virus PBCV-1 [TaxId: 10506] [56102] (3)
   2. mRNA capping enzyme alpha subunit [90032]
      1. Yeast (Candida albicans) [TaxId: 5476] [90033] (1)
4. RNA ligase [103286] (2)
   1. RNA ligase 2, N-terminal domain [103287]
      1. Bacteriophage T4 [TaxId: 10665] [103288] (1)
   2. RNA editing ligase MP52 [118125]
      1. Trypanosoma brucei [TaxId: 5691] [118126] (1)
         SQ P82863 52-316

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk