Structural Classification of Proteins
home mail help root up expand collapse

Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain

has a circularly permuted topology
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: ATP-grasp [56058]
    Consists of two subdomains with different alpha+beta folds
    shares functional and structural similarities with the PIPK and protein kinase superfamilies
  4. Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain [56091]
    has a circularly permuted topology
    link to SUPERFAMILY database - Superfamily

Families:

  1. ATP-dependent DNA ligase catalytic domain [56092] (3)
    1. ATP-dependent DNA ligase, N-terminal domain [56093]
      1. Bacteriophage T7 [TaxId: 10760] [56094] (1)
        1. 1a0i picpicxref
          complexed with atp; mutant
          1. region a:2-240 [41577] picpiclink
      2. Chlorella virus PBCV-1 [TaxId: 10506] [56095] (7)
        1. 1fvi picpicxref
          complexed with amp, so4; mutant
          1. region a:2-189 [41578] picpiclink
        2. 2q2t picpicxref
          automatically matched to d1p8la2
          complexed with amp, omc
          1. region a:2-189 [150015] picpiclink
        3. 2q2u picpicxrefxrefxrefxref
          automatically matched to d1p8la2
          complexed with omc
          1. region a:2-189 [150017] picpiclink
        4. 2q2u picpicxrefxrefxrefxref
          automatically matched to d1p8la2
          complexed with omc
          1. region b:2-189 [150019] picpiclink
        5. 2q2u picpicxrefxrefxrefxref
          automatically matched to d1p8la2
          complexed with omc
          1. region c:2-189 [150021] picpiclink
        6. 2q2u picpicxrefxrefxrefxref
          automatically matched to d1p8la2
          complexed with omc
          1. region d:2-189 [150023] picpiclink
        7. 1p8l picpicxref
          complexed with amp
          1. region a:2-189 [94364] picpiclink
    2. DNA ligase I (LIG1) [118122]
      1. Human (Homo sapiens) [TaxId: 9606] [118123] (1)
        SQ P18858 262-901
        1. 1x9n picpicxrefxref
          complexed with amp, doc
          1. region a:534-753 [115004] picpiclink
  2. Adenylation domain of NAD+-dependent DNA ligase [56096] (3)
    1. Adenylation domain of NAD+-dependent DNA ligase [56097]
      contains additional, N-terminal all-alpha subdomain
      1. Bacillus stearothermophilus [TaxId: 1422] [56098] (1)
        1. 1b04 picpic
          1. chain a [41579] picpiclink
          2. chain b [41580] picpiclink
      2. Thermus filiformis [TaxId: 276] [56099] (2)
        1. 1dgs picpicxrefxref
          complexed with amp, zn
          1. region a:1-314 [41581] picpiclink
          2. region b:2001-2314 [41582] picpiclink
        2. 1v9p picpicxrefxref
          complexed with amp, zn
          1. region a:1-317 [100546] picpiclink
          2. region b:2001-2317 [100549] picpiclink
      3. Enterococcus faecalis [TaxId: 1351] [118124] (2)
        SQ Q837V6 5-317
        1. 1ta8 picpic
          complexed with gol, nmn, so4
          1. chain a [112375] picpiclink
        2. 1tae picpic
          complexed with na, nad, so4
          1. chain a [112376] picpiclink
          2. chain b [112377] picpiclink
          3. chain c [112378] picpiclink
          4. chain d [112379] picpiclink
  3. mRNA capping enzyme [56100] (2)
    1. RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain [56101]
      1. Chlorella virus PBCV-1 [TaxId: 10506] [56102] (3)
        1. 1ckm picpicxref
          complexed with gtp
          1. region a:11-238 [41585] picpiclink
          2. region b:11-238 [41586] picpiclink
        2. 1ckn picpicxref
          complexed with gpl, gtp, mn, so4
          1. region a:11-238 [41587] picpiclink
          2. region b:11-238 [41588] picpiclink
        3. 1cko picpicxref
          complexed with gp3, zn
          1. region a:11-238 [41589] picpiclink
    2. mRNA capping enzyme alpha subunit [90032]
      1. Yeast (Candida albicans) [TaxId: 5476] [90033] (1)
        1. 1p16 picpicxref
          complexed with the phosphorylated carboxyl-terminal peptide of RNA polymerase II, chains C and D
          complexed with g, gtp, mse, po4, sep; mutant
          1. region a:1-245 [87662] picpiclink
          2. region b:1-245 [87664] picpiclink
  4. RNA ligase [103286] (2)
    1. RNA ligase 2, N-terminal domain [103287]
      1. Bacteriophage T4 [TaxId: 10665] [103288] (1)
        1. 1s68 picpic
          complexed with amp
          1. chain a [98591] picpiclink
    2. RNA editing ligase MP52 [118125]
      1. Trypanosoma brucei [TaxId: 5691] [118126] (1)
        SQ P82863 52-316
        1. 1xdn picpic
          complexed with atp, mg
          1. chain a [115168] picpiclink
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk