Structural Classification of Proteins
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Fold: Profilin-like

core: 2 alpha-helices and 5-stranded antiparallel sheet: order 21543; 3 layers: alpha/beta/alpha

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Profilin-like [55769]
    core: 2 alpha-helices and 5-stranded antiparallel sheet: order 21543; 3 layers: alpha/beta/alpha

Superfamilies:

  1. Profilin (actin-binding protein) [55770] (1) picpic
    alpha-beta(2)-alpha-beta(5)-alpha
    link to SUPERFAMILY database - Superfamily
  2. GAF domain-like [55781] (4) picpic
    alpha(2)-beta(3)-alpha-beta(3)-alpha; antiparallel beta-sheet: order 321654
    link to SUPERFAMILY database - Superfamily
  3. PYP-like sensor domain (PAS domain) [55785] (7) picpic
    alpha-beta(2)-alpha(2)-beta(3)
    link to SUPERFAMILY database - Superfamily
  4. Pheromone-binding domain of LuxR-like quorum-sensing transcription factors [75516] (1) picpic
    alpha(2)-beta(2)-alpha(2)-beta(3)-alpha; possibly related to the PAS domain
    link to SUPERFAMILY database - Superfamily
  5. Sensory domain-like [103190] (3) picpic
    alpha(2)-beta(2)-alpha(2)-beta(3); possibly related to the PAS domain
    link to SUPERFAMILY database - Superfamily
  6. SNARE-like [64356] (4) picpic
    beta(2)-alpha-beta(3)-alpha(2)
    link to SUPERFAMILY database - Superfamily
  7. Roadblock/LC7 domain [103196] (1) picpic
    alpha-beta(2)-alpha-beta(3)-alpha; structurally most similar to the SNARE-like superfamily with a circular permutation of the terminal helices
    link to SUPERFAMILY database - Superfamily
  8. YeeU-like [143737] (1) picpic
    beta(2)-alpha-beta(3); 2 layers, a/b; there is an oligomerization interface instead of the 'missing' helical layer
    link to SUPERFAMILY database - Superfamily
  9. GlcG-like [143744] (1) picpic
    alpha-beta(2)-alpha(3)-beta(2)-alpha; similar to the Roadblock/LC7 domain
    link to SUPERFAMILY database - Superfamily
  10. YNR034W-A-like [160683] (1) picpic

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk