Structural Classification of Proteins
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Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Class II aaRS and biotin synthetases [55680]
    contains large mixed beta-sheet
  4. Superfamily: Class II aaRS and biotin synthetases [55681]
    link to SUPERFAMILY database - Superfamily
  5. Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain [55682]

Protein Domains:

  1. Seryl-tRNA synthetase (SerRS) [55683]
    1. Thermus thermophilus, strain hb27 [TaxId: 274] [55684] (4) picpic
  2. Lysyl-tRNA synthetase (LysRS) [55685]
    contains an insertion of LEM/SAP-like HeH motif, residues 337-379
    1. Escherichia coli, gene lysU [TaxId: 562] [55686] (5) picpic
    2. Escherichia coli, gene lysS [TaxId: 562] [55687] (2) picpic
  3. Histidyl-tRNA synthetase (HisRS) [55688]
    1. Escherichia coli [TaxId: 562] [55689] (7) picpic
    2. Staphylococcus aureus [TaxId: 1280] [55690] (1) picpic
    3. Thermus thermophilus [TaxId: 274] [55691] (3) picpic
    4. Archaeon Thermoplasma acidophilum [TaxId: 2303] [143637] (2) picpic
      SQ Q9HLX5 3-329
  4. Glycyl-tRNA synthetase (GlyRS) [55692]
    1. Thermus thermophilus [TaxId: 274] [55693] (3) picpic
  5. Threonyl-tRNA synthetase (ThrRS) [55694]
    1. Escherichia coli [TaxId: 562] [55695] (5) picpic
    2. Staphylococcus aureus [TaxId: 1280] [103154] (2) picpic
  6. Aspartyl-tRNA synthetase (AspRS) [55696]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [55697] (3) picpic
    2. Archaeon Pyrococcus kodakaraensis [TaxId: 311400] [55698] (1) picpic
    3. Thermus thermophilus, AspRS-2 [TaxId: 274] [90008] (1) picpic
      non-discriminating and archaeal-type enzyme
    4. Escherichia coli [TaxId: 562] [55699] (3) picpic
    5. Thermus thermophilus, AspRS-1 [TaxId: 274] [55700] (3) picpic
  7. Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS [55701]
    1. Thermus thermophilus [TaxId: 274] [55702] (9) picpic
      identical sequence to Thermus aquaticus, TaxId: 271
  8. Phenyl-tRNA synthetase (PheRS) beta subunit, PheT, central domain [55703]
    this domain is non-catalytic
    1. Thermus thermophilus [TaxId: 274] [55704] (9) picpic
      identical sequence to Thermus aquaticus, TaxId: 271
  9. Glycyl-tRNA synthetase (GlyRS) alpha chain [75504]
    1. Thermotoga maritima [TaxId: 2336] [75505] (1) picpic
      TM0216
  10. Alanyl-tRNA synthetase (AlaRS) [103155]
    1. Aquifex aeolicus [TaxId: 63363] [103156] (7) picpic
  11. Prolyl-tRNA synthetase (ProRS) [64347]
    1. Thermus thermophilus [TaxId: 274] [64348] (4) picpic
    2. Arhaeon (Methanothermobacter thermautotrophicus) [TaxId: 145262] [90009] (4) picpic
    3. Archaeon (Methanocaldococcus jannaschii) [TaxId: 2190] [90010] (1) picpic
  12. The aaRS-like accessory subunit of mitochondrial polymerase gamma, N-terminal domain [64349]
    1. Mouse (Mus musculus) [TaxId: 10090] [64350] (2) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [143638] (4) picpic
      SQ Q9UHN1 66-355
  13. Asparagine synthetase [55705]
    1. Escherichia coli [TaxId: 562] [55706] (2) picpic
  14. Hypothetical protein PF1951 [103157]
    1. Archaeon Pyrococcus furiosus [TaxId: 2261] [103158] (1) picpic
      AspRS-related protein
  15. ATP phosphoribosyltransferase regulatory subunit HisZ [118058]
    shares histidine-binding site with the HisRS catalytic domain
    1. Thermotoga maritima [TaxId: 2336] [118059] (1) picpic
      SQ Q9X0D3
    2. Lactococcus lactis [TaxId: 1358] [143639] (8) picpic
      SQ Q02147 6-323
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk