Structural Classification of Proteins
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Family: Intein endonuclease

duplication: contains tandem repeat of this fold

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Homing endonuclease-like [55603]
    alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243
  4. Superfamily: Homing endonucleases [55608]
    link to SUPERFAMILY database - Superfamily
  5. Family: Intein endonuclease [55614]
    duplication: contains tandem repeat of this fold

Protein Domains:

  1. VMA1-derived endonuclease (VDE) PI-SceI [55615]
    homing endonuclease with protein splicing activity
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [55616] (7)
      SQ P17255 284-737
      1. 1jva picpicxref
        mutant
        1. region a:464-581 [77176] picpiclink
        2. region a:582-698 [77177] picpiclink
        3. region b:464-581 [77179] picpiclink
        4. region b:582-698 [77180] picpiclink
      2. 1ef0 picpicxref
        complexed with zn
        1. region a:181-298 [40577] picpiclink
        2. region a:299-415 [40578] picpiclink
        3. region b:181-298 [40579] picpiclink
        4. region b:299-415 [40580] picpiclink
      3. 1dfa picpicxref
        1. region a:181-298 [40575] picpiclink
        2. region a:299-415 [40576] picpiclink
      4. 1vde picpicxref
        1. region a:181-298 [40581] picpiclink
        2. region a:299-415 [40582] picpiclink
        3. region b:181-298 [40583] picpiclink
        4. region b:299-415 [40584] picpiclink
      5. 1um2 picpicxref
        mutant
        1. region a:464-581 [107947] picpiclink
        2. region a:582-698 [107948] picpiclink
        3. region b:464-581 [107950] picpiclink
        4. region b:582-698 [107951] picpiclink
      6. 1lwt picpicxref
        complexed with mse
        1. region a:181-298 [78279] picpiclink
        2. region a:299-415 [78280] picpiclink
      7. 1lws picpicxref
        complexed with ca, mse
        1. region a:181-298 [78276] picpiclink
        2. region a:299-415 [78277] picpiclink
  2. PI-Pfui intein [55617]
    1. Archaeon Pyrococcus furiosus [TaxId: 2261] [55618] (1)
      1. 1dq3 picpicxrefxref
        complexed with zn
        1. region a:129-226 [40585] picpiclink
        2. region a:227-335 [40586] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk