Structural Classification of Proteins
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Superfamily: FAD/NAD-linked reductases, dimerisation (C-terminal) domain

both first two domains are of same beta/beta/alpha fold
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: CO dehydrogenase flavoprotein C-domain-like [55423]
    core: beta(3,4)-alpha(3); alpha+beta sandwich
  4. Superfamily: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424]
    both first two domains are of same beta/beta/alpha fold
    link to SUPERFAMILY database - Superfamily

Families:

  1. FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (22)
    1. Glutathione reductase [55426]
      1. Human (Homo sapiens) [TaxId: 9606] [55427] (17) picpic
      2. Plasmodium falciparum [TaxId: 5833] [89990] (1) picpic
      3. Escherichia coli [TaxId: 562] [55428] (4) picpic
    2. Trypanothione reductase [55429]
      1. Crithidia fasciculata [TaxId: 5656] [55430] (6) picpic
      2. Trypanosoma cruzi [TaxId: 5693] [55431] (6) picpic
    3. Mammalian thioredoxin reductase [64329]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [64330] (1) picpic
    4. Apoptosis-inducing factor (AIF) [75489]
      contains a large loop insertion in this domain
      1. Human (Homo sapiens) [TaxId: 9606] [75490] (1) picpic
      2. Mouse (Mus musculus) [TaxId: 10090] [75491] (1) picpic
    5. NADH peroxidase [55432]
      1. Enterococcus faecalis [TaxId: 1351] [55433] (8) picpic
    6. NADH-dependent ferredoxin reductase, BphA4 [55434]
      1. Pseudomonas sp., KKS102 [TaxId: 306] [55435] (2) picpic
    7. Putidaredoxin reductase [103115]
      1. Pseudomonas putida [TaxId: 303] [103116] (2) picpic
    8. Dihydrolipoamide dehydrogenase [55436]
      1. Pseudomonas putida [TaxId: 303] [55437] (1) picpic
      2. Pseudomonas fluorescens [TaxId: 294] [55438] (1) picpic
      3. Azotobacter vinelandii [TaxId: 354] [55439] (1) picpic
      4. Bacillus stearothermophilus [TaxId: 1422] [55440] (1) picpic
      5. Neisseria meningitidis [TaxId: 487] [55441] (2) picpic
      6. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64331] (3) picpic
      7. Garden pea (Pisum sativum) [TaxId: 3888] [55442] (1) picpic
      8. Mycobacterium tuberculosis [TaxId: 1773] [118041] (1) picpic
        SQ O53355
    9. NADH-dependent 2-ketopropyl coenzyme M oxidoreductase/carboxylase [82726]
      1. Xanthobacter sp., py2 [TaxId: 35809] [82727] (6) picpic
    10. Flavocytochrome c sulfide dehydrogenase, FCSD, flavin-binding subunit [55443]
      rudiment "interface" domain of smaller size; beta(3)-alpha
      1. Purple phototrophic bacterium (Chromatium vinosum) [TaxId: 1049] [55444] (1) picpic
    11. NADH oxidase /nitrite reductase [118042]
      1. Pyrococcus furiosus [TaxId: 2261] [118043] (1) picpic
        SQ Q8U1K9
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk