Structural Classification of Proteins
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Fold: Bacillus chorismate mutase-like

core: beta-alpha-beta-alpha-beta(2); mixed beta-sheet: order: 1423, strand 4 is antiparallel to the rest

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Bacillus chorismate mutase-like [55297]
    core: beta-alpha-beta-alpha-beta(2); mixed beta-sheet: order: 1423, strand 4 is antiparallel to the rest

Superfamilies:

  1. YjgF-like [55298] (2)
    forms trimers with three closely packed beta-sheets; possibly related to the IspF (d.79.5) and 4'-phosphopantetheinyl transferase superfamilies (d.150.1)
    link to SUPERFAMILY database - Superfamily
    1. YjgF/L-PSP [55299] (15)
      some members possess an endoribonuclease activity inhibiting mRNA translation
      1. Conserved 'hypothetical' protein YjgF [55300]
        1. Escherichia coli [TaxId: 562] [55301] (1) picpic
        2. Haemophilus influenzae [TaxId: 727] [82719] (1) picpic
          YjgF homologue HI0719
      2. Hypothetical protein YjgH [103075]
        1. Escherichia coli [TaxId: 562] [103076] (1) picpic
      3. Purine regulatory protein YabJ [55302]
        1. Bacillus subtilis [TaxId: 1423] [55303] (1) picpic
        2. Clostridium thermocellum [TaxId: 1515] [118024] (1) picpic
          SQ Q4CI45
      4. Highdosage growth inhibitor YER057cp (YEO7_YEAST) [64319]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64320] (1) picpic
      5. 14.5 kda translational inhibitor protein, L-PSP [89979]
        mammalian tumor associated antigen UK114
        1. Human (Homo sapiens) [TaxId: 9606] [89980] (1) picpic
        2. Goat (Capra hircus) [TaxId: 9925] [103077] (1) picpic
        3. Rat (Rattus norvegicus) [TaxId: 10116] [103078] (1) picpic
          Perchloric acid soluble protein
      6. Hypothetical protein ST0811 [143521]
        1. Sulfolobus tokodaii [TaxId: 111955] [143522] (2) picpic
          SQ Q973T6 1-124
      7. Putative endonuclease APE1501 [143523]
        1. Aeropyrum pernix [TaxId: 56636] [143524] (1) picpic
          SQ Q9YBU8 4-119
      8. Putative protein synthesis inhibitor TM0215 [143525]
        1. Thermotoga maritima [TaxId: 2336] [143526] (2) picpic
          SQ Q9WY58 2-127
      9. Hypothetical protein SPy2060 [143527]
        1. Streptococcus pyogenes [TaxId: 1314] [143528] (12) picpic
          SQ Q99XS4 3-122
      10. Putative translation intiation inhibitor TTHA0137 [143529]
        1. Thermus thermophilus [TaxId: 274] [143530] (13) picpic
          SQ Q5SM06 1-124
      11. Hypothetical protein SO1960 [160498]
        1. Shewanella oneidensis [TaxId: 70863] [160499] (3) picpic
          SQ Q8EFL1 2-153
    2. Chorismate mutase [55304] (3)
      1. Chorismate mutase [55305]
        1. Bacillus subtilis [TaxId: 1423] [55306] (6) picpic
        2. Thermus thermophilus [TaxId: 274] [89981] (3) picpic
        3. Clostridium thermocellum [TaxId: 1515] [118025] (1) picpic
          SQ Q5KXU6 5-114 # 53% sequence identity
  2. IpsF-like [69765] (1)
    forms trimers with three closely packed beta-sheets; possible link between the YjgF-like (d.79.1) and 4'-phosphopantetheinyl transferase superfamilies (d.150.1)
    link to SUPERFAMILY database - Superfamily
    1. IpsF-like [69766] (5)
      1. 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF [69767]
        1. Escherichia coli [TaxId: 562] [69768] (11) picpic
          SQ P62617 ! SQ P36663
        2. Haemophilus influenzae [TaxId: 727] [75479] (3) picpic
        3. Thermus thermophilus [TaxId: 274] [82720] (4) picpic
        4. Shewanella oneidensis [TaxId: 70863] [118026] (1) picpic
          SQ Q8EBR3
      2. IspD/ispF bifunctional enzyme, MECDP synthase domain [118027]
        1. Campylobacter jejuni [TaxId: 197] [118028] (2) picpic
          SQ Q9PM68
  3. Tubulin C-terminal domain-like [55307] (1)
    link to SUPERFAMILY database - Superfamily
    1. Tubulin, C-terminal domain [55308] (9)
      1. Cell-division protein FtsZ [55309]
        1. Archaeon Methanococcus jannaschii [TaxId: 2190] [55310] (7) picpic
          SQ Q57816 23-360
        2. Pseudomonas aeruginosa [TaxId: 287] [89982] (2) picpic
        3. Mycobacterium tuberculosis [TaxId: 1773] [111032] (7) picpic
          SQ O08378
        4. Thermotoga maritima [TaxId: 2336] [118029] (1) picpic
          SQ O08398 22-335
      2. Tubulin alpha-subunit [55311]
        1. Pig (Sus scrofa) [TaxId: 9823] [55312] (3) picpic
        2. Cow (Bos taurus) [TaxId: 9913] [64321] (6) picpic
          SQ P02550
        3. Prosthecobacter dejongeii [TaxId: 48465] [160500] (3) picpic
          SQ Q8GCC5 253-432
          bacterial tubulin BtubA
      3. Tubulin beta-subunit [55313]
        1. Pig (Sus scrofa) [TaxId: 9823] [55314] (1) picpic
        2. Cow (Bos taurus) [TaxId: 9913] [64322] (8) picpic
          SQ P02554
  4. L30e-like [55315] (3)
    link to SUPERFAMILY database - Superfamily
    1. L30e/L7ae ribosomal proteins [55316] (11)
      1. Eukaryotic ribosomal protein L30 (L30e) [55317]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [55318] (4) picpic
          SQ P14120
        2. Archaeon Thermococcus celer [TaxId: 2264] [89986] (8) picpic
      2. Ribosomal protein L7ae [55319]
        1. Archaeon Pyrococcus abyssi [TaxId: 29292] [103081] (2) picpic
        2. Archaeon Haloarcula marismortui [TaxId: 2238] [55320] (58) picpic
          SQ P12743
        3. Archaeon Methanococcus jannaschii [TaxId: 2190] [111033] (3) picpic
          SQ P54066
        4. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [111034] (1) picpic
          SQ O29494 # AF0764
        5. Aeropyrum pernix [TaxId: 56636] [160501] (1) picpic
          SQ Q9YAX7 4-127
        6. Pyrococcus furiosus [TaxId: 2261] [160502] (1) picpic
          SQ Q8U160 3-123
        7. Cryptosporidium parvum [TaxId: 5807] [160503] (1) picpic
          SQ Q7YYQ3 17-131
      3. Spliceosomal 15.5kd protein [55321]
        1. Human (Homo sapiens) [TaxId: 9606] [55322] (4) picpic
      4. Small nuclear ribonucleoprotein-associated protein 1, Snu13p [160504]
        1. Saccharomyces cerevisiae [TaxId: 4932] [160505] (3) picpic
          SQ P39990 1-126! SQ P39990 2-126
    2. RNA 2'-O ribose methyltransferase substrate binding domain [75480] (2)
      1. RrmA (RrmH), N-terminal domain [75481]
        23S rRNA methyltransferase; proposed gene names are as appear in the original publication (and the PDB entry)
        1. Thermus thermophilus [TaxId: 274] [75482] (1) picpic
      2. RlmB, N-terminal domain [82721]
        23S rRNA G2251 2'O-methytransferase
        1. Escherichia coli [TaxId: 562] [82722] (1) picpic
    3. ERF1/Dom34 C-terminal domain-like [55323] (4)
      1. C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 [55324]
        contains a large insertion forming a separate (sub)domain
        1. Human (Homo sapiens) [TaxId: 9606] [55325] (1) picpic
      2. Cell division protein pelota [160506]
        1. Human (Homo sapiens) [TaxId: 9606] [160507] (1) picpic
          SQ Q9BRX2 261-371
        2. Thermoplasma acidophilum [TaxId: 2303] [160508] (1) picpic
          SQ Q9HJ74 244-338
      3. Dom34 [160509]
        1. Saccharomyces cerevisiae [TaxId: 4932] [160510] (3) picpic
          SQ P33309 278-381
  5. PurM N-terminal domain-like [55326] (1)
    link to SUPERFAMILY database - Superfamily
    1. PurM N-terminal domain-like [55327] (6)
      1. Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain [55328]
        1. Escherichia coli [TaxId: 562] [55329] (1) picpic
      2. Phosphoribosylformylglycinamidine synthase II, domains 1 and 3 [103082]
        duplication: tandem repeats of two PurM-like units arranged like the PurM subunits in the dimer
        1. Thermotoga maritima [TaxId: 2336] [103083] (17) picpic
          TM1246
      3. FGAM synthase PurL, PurM-like module, N1 and N2 domains [111035]
        1. Salmonella typhimurium [TaxId: 90371] [111036] (1) picpic
          SQ P74881
      4. Thiamine monophosphate kinase (ThiL) N-terminal domain [118030]
        1. Aquifex aeolicus [TaxId: 63363] [118031] (9) picpic
          SQ O67883
      5. Selenide, water dikinase SelD [160511]
        1. Aquifex aeolicus [TaxId: 63363] [160512] (7) picpic
          SQ O67139 1-154! SQ O67139 28-154
      6. Hydrogenase expression/formation protein HypE [160513]
        1. Thermococcus kodakaraensis [TaxId: 311400] [160514] (2) picpic
          SQ Q5JII7 41-155
  6. Holliday junction resolvase RusA [103084] (1)
    link to SUPERFAMILY database - Superfamily
    1. Holliday junction resolvase RusA [103085] (1)
      1. Holliday junction resolvase RusA [103086]
        1. Escherichia coli [TaxId: 562] [103087] (1) picpic
  7. OmpA-like [103088] (1)
    link to SUPERFAMILY database - Superfamily
    1. OmpA-like [103089] (3)
      Pfam 00691
      1. Peptidoglycan-associated lipoprotein, PAL, periplasmic domain [103090]
        1. Escherichia coli [TaxId: 562] [103091] (5) picpic
        2. Haemophilus influenzae [TaxId: 727] [143531] (1) picpic
          SQ P10324 20-153
      2. Outer membrane protein class 4, RmpM, C-terminal domain [103092]
        1. Neisseria meningitidis [TaxId: 487] [103093] (1) picpic
  8. YueI-like [160515] (1)
    1. YueI-like [160516] (1)
      Pfam 07997; DUF1694
      1. Uncharacterized protein YueI [160517]
        1. Bacillus subtilis [TaxId: 1423] [160518] (2) picpic
          SQ O32092 3-130
  9. BB2672-like [160519] (1)
    contains extra N-terminal strand and a beta-hairpin insertion between strands 3 and 4 that packs against the main beta-sheet
    1. BB2672-like [160520] (2)
      Pam 06684; DUF1185
      1. Uncharacterized protein BB2672 [160521]
        1. Bordetella bronchiseptica [TaxId: 518] [160522] (3) picpic
          SQ Q7WJ28 2-192
      2. Uncharacterized protein SPO0826 [160523]
        1. Silicibacter pomeroyi [TaxId: 89184] [160524] (1) picpic
          SQ Q5LV76 3-171
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk