Structural Classification of Proteins
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Family: Interleukin 8-like chemokines

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: IL8-like [54116]
    beta(3)-alpha
  4. Superfamily: Interleukin 8-like chemokines [54117]
    form dimers with different dimerisation modes
    link to SUPERFAMILY database - Superfamily
  5. Family: Interleukin 8-like chemokines [54118]

Protein Domains:

  1. Interleukin-8, IL-8 [54119]
    1. Human (Homo sapiens) [TaxId: 9606] [54120] (9) picpic
  2. Platelet factor 4, PF4 [54121]
    1. Cow (Bos taurus) [TaxId: 9913] [54122] (1) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [54123] (6) picpic
  3. IP-10/CXCL10 [82573]
    1. Human (Homo sapiens) [TaxId: 9606] [82574] (4) picpic
  4. Melanoma growth stimulating activity (MGSA) [54124]
    1. Human (Homo sapiens) [TaxId: 9606] [54125] (3) picpic
  5. IL-8/MGSA chimeric protein CIL-8M [54126]
    IL-8: residues 1-53; MGSA: residues 54-72
    1. Human (Homo sapiens) [TaxId: 9606] [54127] (1) picpic
  6. Macrophage inflammatory protein, MIP [54128]
    has different dimerisation mode
    1. Human (Homo sapiens), 1-beta [TaxId: 9606] [54129] (3) picpic
    2. Human (Homo sapiens), 1-alpha [TaxId: 9606] [54130] (2) picpic
    3. Human (Homo sapiens), ccl20/mip-3a [TaxId: 9606] [75340] (4) picpic
    4. Mouse (Mus musculus), ccl20/mip-3a [TaxId: 10090] [64214] (1) picpic
    5. Kaposi's sarcoma-associated herpesvirus, VMIP-II [TaxId: 37296] [54131] (10) picpic
      anti-HIV chemokine
  7. RANTES (regulated upon activation, normal T-cell expressed and secreted) [54132]
    has different dimerisation mode
    1. Human (Homo sapiens) [TaxId: 9606] [54133] (9) picpic
      SQ P13501 25-91
  8. Monocyte chemoattractant protein-1 (MCP-1, MCAF) [54134]
    1. Human (Homo sapiens) [TaxId: 9606] [54135] (9) picpic
  9. Monocyte chemoattractant protein-2 (MCP-2) [54136]
    1. Human (Homo sapiens) [TaxId: 9606] [54137] (1) picpic
  10. CC chemokine I-309 [54138]
    1. Human (Homo sapiens) [TaxId: 9606] [54139] (1) picpic
  11. Eotaxin [54140]
    1. Human (Homo sapiens) [TaxId: 9606] [54141] (2) picpic
  12. Eotaxin-2 [54142]
    1. Human (Homo sapiens) [TaxId: 9606] [54143] (2) picpic
  13. Eotaxin-3 [75341]
    1. Human (Homo sapiens) [TaxId: 9606] [75342] (2) picpic
  14. Lymphotactin [69632]
    1. Human (Homo sapiens) [TaxId: 9606] [69633] (2) picpic
  15. Monocyte chemoattractant protein-3 (MCP-3) [54144]
    1. Human (Homo sapiens) [TaxId: 9606] [54145] (2) picpic
  16. Chemokine domain of fractalkine [54146]
    1. Human (Homo sapiens) [TaxId: 9606] [54147] (2) picpic
  17. Platelet basic protein, PBP [54148]
    synonym: Small inducible cytokine B7; Neutrophil-activating peptide-2 (NAP-2), Connective tissue activating peptide-III (CTAP-III)
    1. Human (Homo sapiens) [TaxId: 9606] [54149] (3) picpic
  18. Stromal cell-derived factor-1 (SDF-1) [54150]
    1. Human (Homo sapiens) [TaxId: 9606] [54151] (7) picpic
  19. Macrophage inflammatory protein-2 [54152]
    1. Mouse (Mus musculus) [TaxId: 10090] [54153] (1) picpic
  20. Chemokine hcc-2 (macrophage inflammatory protein-5) [54154]
    1. Human (Homo sapiens) [TaxId: 9606] [54155] (1) picpic
  21. Gro beta [54156]
    1. Human (Homo sapiens) [TaxId: 9606] [54157] (1) picpic
  22. Myeloid progenitor inhibitory factor-1 (MPIF-1) [64215]
    1. Human (Homo sapiens) [TaxId: 9606] [64216] (1) picpic
  23. Thymus and activation-regulated chemokine, TRAC [102730]
    1. Human (Homo sapiens) [TaxId: 9606] [102731] (2) picpic
  24. Small inducible cytokine b11 (CXCL11/I-TAC) [102732]
    1. Human (Homo sapiens) [TaxId: 9606] [102733] (1) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk