Structural Classification of Proteins
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Superfamily: Nucleotide cyclase

common fold is elaborated with additional secondary structures
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Ferredoxin-like [54861]
    alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
  4. Superfamily: Nucleotide cyclase [55073]
    common fold is elaborated with additional secondary structures
    link to SUPERFAMILY database - Superfamily

Families:

  1. Adenylyl and guanylyl cyclase catalytic domain [55074] (5)
    Pfam 00211
    structurally similar to the "palm" domain of DNA/RNA polymerase superfamily
    1. Type II adenylyl cyclase C2 domain [55075]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [55076] (5) picpic
        SQ P26769 879-1077
    2. Adenylyl cyclase VC1, domain C1a [55077]
      1. Dog (Canis familiaris) [TaxId: 9615] [55078] (11) picpic
        SQ P30803 458-646
    3. Adenylyl cyclase IIC1, domain C2a [55079]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [55080] (7) picpic
    4. Receptor-type monomeric adenylyl cyclase [55081]
      1. Trypanosome (Trypanosoma brucei), different isoform [TaxId: 5691] [55082] (2) picpic
    5. Adenylate cyclase CyaC [117982]
      1. Spirulina platensis [TaxId: 118562] [117983] (6) picpic
        SQ O32393 1004-1200
  2. GGDEF domain [117984] (1)
    Pfam 00990; less decorated than the adenylyl/guanylyl cyclase domain
    1. Response regulator PleD, C-terminal domain [117985]
      Diguanylate cyclase
      1. Caulobacter crescentus [TaxId: 155892] [117986] (3) picpic
        SQ Q9A5I5

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk