Structural Classification of Proteins
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Superfamily: dsRNA-binding domain-like

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: dsRBD-like [54767]
    alpha-beta(3)-alpha; 2 layers: alpha/beta
  4. Superfamily: dsRNA-binding domain-like [54768]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Double-stranded RNA-binding domain (dsRBD) [54769] (15)
    Pfam 00035
    1. Double-stranded RNA-binding protein A, second dsRBD [54770]
      1. Xenopus laevis [TaxId: 8355] [54771] (1) picpic
    2. Staufen, domain III [54772]
      1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [54773] (2) picpic
    3. dsRNA-dependent protein kinase pkr [54774]
      contains tandem repeat of two dsRBD
      1. Human (Homo sapiens) [TaxId: 9606] [54775] (1) picpic
      2. Mouse (Mus musculus) [TaxId: 10090] [143201] (2) picpic
        SQ Q03963 1-85! SQ Q03963 96-181
    4. RNase III, C-terminal domain [54776]
      1. Thermotoga maritima [TaxId: 2336] [82644] (1) picpic
      2. Aquifex aeolicus [TaxId: 63363] [102927] (19) picpic
      3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [110913] (3) picpic
        SQ Q02555 364-447 ! SQ Q02555 366-453 ! SQ Q02555 363-443
    5. staufen homolog 2 [110914]
      1. Mouse (Mus musculus) [TaxId: 10090] [110915] (1) picpic
        SQ Q9D5N7 3-78
    6. ATP-dependent RNA helicase A, Dhx9 [117901]
      formerly hypothetical protein bab28848
      1. Mouse (Mus musculus) [TaxId: 10090] [117902] (2) picpic
        SQ O70133 4-89, 168-262
    7. tRNA-dihydrouridine synthase 2-like, Dus2l (2310016k04Rik) [117903]
      1. Mouse (Mus musculus) [TaxId: 10090] [117904] (1) picpic
        SQ Q9D7B1 350-464
    8. dsRNA-specific editase 1 [143202]
      duplication: contains two dsRBD domains
      1. Rat (Rattus norvegicus) [TaxId: 10116] [143203] (2) picpic
        SQ P51400 231-301! SQ P51400 74-146
    9. Interferon-inducible double stranded RNA-dependent protein kinase activator A [143204]
      1. Human (Homo sapiens) [TaxId: 9606] [143205] (1) picpic
        SQ O75569 32-104
    10. Dgcr8 protein [143206]
      1. Human (Homo sapiens) [TaxId: 9606] [143207] (1) picpic
        SQ Q8WYQ5 502-586
    11. TAR RNA-binding protein 2 [143208]
      duplication: contains three dsRBD
      1. Human (Homo sapiens) [TaxId: 9606] [143209] (1) picpic
        SQ Q15633 150-225
    12. Spermatid perinuclear RNA-binding protein [143210]
      1. Human (Homo sapiens) [TaxId: 9606] [143211] (1) picpic
        SQ Q96SI9 378-461
  2. The homologous-pairing domain of Rad52 recombinase [82645] (1)
    contains N- and C-terminal extensions to the common fold involved in the oligomerization
    1. The homologous-pairing domain of Rad52 recombinase [82646]
      forms an undecameric ring structure; binds to ssDNA and dsDNA
      1. Human (Homo sapiens) [TaxId: 9606] [82647] (2) picpic
  3. Ribosomal S5 protein, N-terminal domain [54778] (3)
    1. Ribosomal S5 protein, N-terminal domain [54779]
      lacks the N-terminal helix
      1. Bacillus stearothermophilus [TaxId: 1422] [54780] (1) picpic
      2. Thermus thermophilus [TaxId: 274] [54781] (36) picpic
        SQ P27152
      3. Escherichia coli [TaxId: 562] [160202] (24) picpic
        SQ P0A7W1 9-77
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk