Structural Classification of Proteins
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Superfamily: S-adenosyl-L-methionine-dependent methyltransferases

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: S-adenosyl-L-methionine-dependent methyltransferases [53334]
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. Superfamily: S-adenosyl-L-methionine-dependent methyltransferases [53335]
    link to SUPERFAMILY database - Superfamily

Families:

  1. COMT-like [53336] (3)
    1. Catechol O-methyltransferase, COMT [53337]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [53338] (6) picpic
    2. COMT domain-containing protein 1, COMTD1 [142571]
      1. Human (Homo sapiens) [TaxId: 9606] [142572] (2) picpic
        SQ Q86VU5 44-262
    3. Caffeoyl-CoA O-methyltransferase [142573]
      1. Alfalfa (Medicago sativa) [TaxId: 3879] [142574] (8) picpic
        SQ Q40313 21-247
  2. Plant O-methyltransferase, C-terminal domain [64111] (5)
    1. Chalcone O-methyltransferase [64112]
      1. Alfalfa (Medicago sativa) [TaxId: 3879] [64113] (2) picpic
    2. Isoflavone O-methyltransferase [64114]
      1. Alfalfa (Medicago sativa) [TaxId: 3879] [64115] (2) picpic
    3. Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase [75259]
      1. Alfalfa (Medicago sativa) [TaxId: 3879] [75260] (2) picpic
    4. Aclacinomycin-10-hydroxylase RdmB [102554]
      evolved a different function; binds SAM and SAH
      1. Streptomyces purpurascens [TaxId: 1924] [102555] (4) picpic
        SQ Q54527
    5. Carminomycin 4-O-methyltransferase [110660]
      1. Streptomyces peucetius [TaxId: 1950] [110661] (2) picpic
        SQ Q06528
  3. RNA methyltransferase FtsJ [53339] (1)
    1. RNA methyltransferase FtsJ [53340]
      1. Escherichia coli [TaxId: 562] [53341] (2) picpic
  4. Fibrillarin homologue [53342] (3)
    1. Fibrillarin homologue [53343]
      1. Archaeon Methanococcus jannaschii [TaxId: 2190] [53344] (2) picpic
      2. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [89737] (1) picpic
        AF2087
      3. Archaeon Pyrococcus horikoshii [TaxId: 53953] [102556] (2) picpic
  5. rRNA methyltransferase RlmA [102557] (1)
    1. rRNA methyltransferase RlmA [102558]
      23S rRNA N1-G745 methyltransferase
      1. Escherichia coli [TaxId: 562] [102559] (1) picpic
  6. rRNA methyltransferase AviRa [89738] (1)
    1. rRNA methyltransferase AviRa [89739]
      1. Streptomyces viridochromogenes [TaxId: 1938] [89740] (2) picpic
  7. rRNA adenine dimethylase-like [88784] (5)
    1. rRNA adenine dimethylase [53363]
      contains additional all-alpha C-terminal domain (res.181-248)
      1. Streptococcus pneumoniae, Ermam [TaxId: 1313] [53364] (1) picpic
      2. Bacillus subtilis, Ermc' [TaxId: 1423] [53365] (5) picpic
    2. Transcription factor sc-mtTFB [69555]
      overall structure is very similar to those of Ermc' and Ermam
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [69556] (1) picpic
    3. High level kasugamycin resistance protein KsgA [110662]
      1. Escherichia coli [TaxId: 562] [110663] (1) picpic
        SQ P06992
    4. Probable dimethyladenosine transferase [142575]
      1. Human (Homo sapiens) [TaxId: 9606] [142576] (2) picpic
        SQ Q9UNQ2 36-313
  8. mRNA cap methylase [88785] (3)
    1. Polymerase regulatory subunit VP39 [53361]
      1. Vaccinia virus [TaxId: 10245] [53362] (19) picpic
    2. An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 [89741]
      structurally and functionally similar to VP39
      1. Flavivirus (Dengue virus type 2) [TaxId: 12637] [89742] (3) picpic
        SQ P12823 2495-2756
      2. Dengue virus 2 [TaxId: 11060] [159679] (5) picpic
  9. mRNA cap (Guanine N-7) methyltransferase [102560] (1)
    mRNA capping enzyme
    1. mRNA cap (Guanine N-7) methyltransferase [102561]
      1. Fungus (Encephalitozoon cuniculi) [TaxId: 6035] [102562] (7) picpic
  10. Hypothetical protein MJ0882 [53345] (1)
    1. Hypothetical protein MJ0882 [53346]
      1. Archaeon Methanococcus jannaschii [TaxId: 2190] [53347] (1) picpic
  11. Hypothetical protein HI0319 (YecO) [69544] (1)
    1. Hypothetical protein HI0319 (YecO) [69545]
      1. Haemophilus influenzae [TaxId: 727] [69546] (1) picpic
        structural genomics
  12. Glycine N-methyltransferase [53348] (3)
    1. Glycine N-methyltransferase [53349]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [53350] (16) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [110664] (1) picpic
        SQ Q14749
      3. Mouse (Mus musculus) [TaxId: 10090] [110665] (2) picpic
        SQ Q9QXF8
  13. Arylamine N-methyltransferase [69547] (2)
    1. Phenylethanolamine N-methyltransferase, PNMTase [69548]
      1. Human (Homo sapiens) [TaxId: 9606] [69549] (21) picpic
    2. Indolethylamine N-methyltransferase, INMT [142577]
      1. Human (Homo sapiens) [TaxId: 9606] [142578] (1) picpic
        SQ O95050 5-261
  14. Histamine methyltransferase [75261] (1)
    1. Histamine methyltransferase [75262]
      1. Human (Homo sapiens) [TaxId: 9606] [75263] (12) picpic
  15. Hypothetical Protein YjhP [82469] (1)
    1. Hypothetical Protein YjhP [82470]
      1. Escherichia coli [TaxId: 562] [82471] (1) picpic
  16. Salicylic acid carboxyl methyltransferase (SAMT) [102563] (1)
    1. Salicylic acid carboxyl methyltransferase (SAMT) [102564]
      1. Clarkia breweri [TaxId: 36903] [102565] (1) picpic
  17. Thiopurine S-methyltransferase [102566] (2)
    1. Thiopurine S-methyltransferase [102567]
      1. Pseudomonas syringae [TaxId: 317] [102568] (1) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [142579] (3) picpic
        SQ P51580 17-245
  18. Leucine carboxy methyltransferase Ppm1 [102569] (1)
    1. Leucine carboxy methyltransferase Ppm1 [102570]
      involved in the regulation of protein phosphatase 2a activity
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [102571] (7) picpic
  19. Precorrin-6Y methyltransferase (CbiT) [82472] (1)
    1. Precorrin-6Y methyltransferase (CbiT) [82473]
      1. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [82474] (5) picpic
        MTH146
  20. MraW-like putative methyltransferases [82475] (2)
    1. TM0872, methyltransferase domain [82476]
      contains an inserted alpha helical subdomain
      1. Thermotoga maritima [TaxId: 2336] [82477] (2) picpic
      2. Thermus thermophilus [TaxId: 274] [117678] (1) picpic
        SQ Q5SJD8
  21. N5-glutamine methyltransferase, HemK [89743] (2)
    1. N5-glutamine methyltransferase, HemK [89744]
      contains an N-terminal alpha helical subdomain; res. 13-84
      1. Thermotoga maritima [TaxId: 2336] [89745] (5) picpic
        SQ Q9WYV8
      2. Escherichia coli [TaxId: 562] [110666] (2) picpic
        SQ P37186
  22. Catalytic, N-terminal domain of histone methyltransferase Dot1l [89746] (2)
    1. Catalytic, N-terminal domain of histone methyltransferase Dot1l [89747]
      a non-SET domain nucleosomal histone methyltransferase
      1. Human (Homo sapiens) [TaxId: 9606] [89748] (1) picpic
      2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [110667] (1) picpic
        SQ Q04089 176-581
  23. Guanidinoacetate methyltransferase [69550] (2)
    1. Guanidinoacetate methyltransferase [69551]
      a template structure of protein arginine methyltransferase
      1. Rat (Rattus norvegicus) [TaxId: 10116] [69552] (5) picpic
        SQ P10868
      2. Human (Homo sapiens) [TaxId: 9606] [142580] (3) picpic
        SQ Q14353 8-236
  24. Arginine methyltransferase [53351] (4)
    lacks the last two strands of the common fold replaced with a beta-sandwich oligomerisation subdomain
    1. Arginine methyltransferase, HMT1 [53352]
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [53353] (1) picpic
      2. Rat (Rattus norvegicus) [TaxId: 10116] [64116] (1) picpic
    2. Protein arginine N-methyltransferase 1, PRMT1 [89749]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [89750] (3) picpic
    3. Protein arginine N-methyltransferase 3, PRMT3 [142581]
      1. Human (Homo sapiens) [TaxId: 9606] [142582] (1) picpic
        SQ O60678 221-531
  25. Protein-L-isoaspartyl O-methyltransferase [53354] (5)
    topological variant; strand order 3214567; strand 6 is antiparallel to the rest
    1. Protein-L-isoaspartyl O-methyltransferase [68927]
      1. Thermotoga maritima [TaxId: 2336] [68928] (1) picpic
      2. Archaeon Pyrococcus furiosus [TaxId: 2261] [69553] (4) picpic
      3. Human (Homo sapiens) [TaxId: 9606] [69554] (2) picpic
      4. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [102572] (1) picpic
      5. Sulfolobus tokodaii [TaxId: 111955] [110668] (1) picpic
        SQ Q972K9
  26. Glucose-inhibited division protein B (GidB) [75264] (2)
    1. Glucose-inhibited division protein B (GidB) [75265]
      function unknown
      1. Escherichia coli [TaxId: 562] [75266] (1) picpic
      2. Bacillus subtilis [TaxId: 1423] [117679] (1) picpic
        SQ P25813
  27. tRNA(1-methyladenosine) methyltransferase-like [64117] (4)
    contains additional N-terminal beta-sandwich domain
    1. Probable methyltransferase Rv2118c [64118]
      1. Mycobacterium tuberculosis [TaxId: 1773] [64119] (1) picpic
    2. Hypothetical protein TM0748 [102573]
      1. Thermotoga maritima [TaxId: 2336] [102574] (1) picpic
    3. Hypothetical protein FLJ20628 [142583]
      1. Human (Homo sapiens) [TaxId: 9606] [142584] (2) picpic
        SQ Q9BVS5 149-472
    4. Hypothetical protein Ta0852 [142585]
      forms dimer similar to half-tetramer of the other members but with swapped N-terminal domains; variant topology of the N-terminal domain
      1. Thermoplasma acidophilum [TaxId: 2303] [142586] (1) picpic
        SQ Q9HJW1 6-255
  28. NOL1/NOP2/sun [102575] (3)
    Pfam 01189; contains additional N-terminal 3-helical and ferredoxin-like domains
    1. Hypothetical methyltransferase PH1374 [102576]
      1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [102577] (1) picpic
    2. Ribosomal RNA small subunit methyltransferase B, RsmB (Sun, Fmu/Fmv), C-terminal domain [110669]
      1. Escherichia coli [TaxId: 562] [110670] (2) picpic
        SQ P36929
    3. NOL1R [142587]
      1. Human (Homo sapiens) [TaxId: 9606] [142588] (1) picpic
        SQ Q96P11 133-425
  29. Ribosomal protein L11 methyltransferase PrmA [102578] (1)
    contains additional N-terminal ferredoxin-like domain
    1. PrmA-like protein TTHA0656 (TT0836) [102579]
      1. Thermus thermophilus [TaxId: 274] [102580] (12) picpic
  30. (Uracil-5-)-methyltransferase [102581] (1)
    Pfam 05958
    1. rRNA (Uracil-5-)-methyltransferase RumA, catalytic domain [102582]
      includes an iron-sulfur cluster-binding, alpha+beta sudbomain
      1. Escherichia coli [TaxId: 562] [102583] (3) picpic
  31. Chemotaxis receptor methyltransferase CheR, C-terminal domain [53357] (1)
    contains additional N-terminal all-alpha domain, res. 11-91
    1. Chemotaxis receptor methyltransferase CheR, C-terminal domain [53358]
      1. Salmonella typhimurium [TaxId: 90371] [53359] (2) picpic
  32. C5 cytosine-specific DNA methylase, DCM [88786] (3)
    1. DNA methylase HhaI [53367]
      1. Haemophilus haemolyticus [TaxId: 726] [53368] (20) picpic
        SQ P05102
    2. DNA methylase HaeIII [53371]
      1. Haemophilus aegyptius [TaxId: 197575] [53372] (1) picpic
    3. DNMT2 [53375]
      an enigmatic DNA methyltransferase homologue from mitochondria
      1. Human (Homo sapiens) [TaxId: 9606] [53376] (1) picpic
  33. DNA methylase TaqI, N-terminal domain [88787] (1)
    1. DNA methylase TaqI, N-terminal domain [53369]
      1. Thermus aquaticus [TaxId: 271] [53370] (18) picpic
  34. N6 adenine-specific DNA methylase, DAM [88788] (2)
    1. DNA methylase DpnM [53373]
      1. Streptococcus pneumoniae [TaxId: 1313] [53374] (1) picpic
    2. DNA methylase T4DAM [102584]
      1. Bacteriophage T4 [TaxId: 10665] [102585] (14) picpic
  35. Type II DNA methylase [53377] (3)
    circularly permuted version of the common fold
    1. m.PvuII N4 cytosine-specific DNA methyltransferase [53378]
      1. Proteus vulgaris [TaxId: 585] [53379] (1) picpic
    2. m.RsrI N6 adenosine-specific DNA methyltransferase [53380]
      1. Rhodobacter sphaeroides [TaxId: 1063] [53381] (5) picpic
    3. Methyltransferase mboII [75267]
      1. Moraxella bovis [TaxId: 476] [75268] (1) picpic
  36. Spermidine synthase [69557] (7)
    contains additional N-terminal tetramerisation all-beta domain, res. 1-71
    1. Spermidine synthase [69558]
      polyamine aminopropyltransferase
      1. Thermus thermophilus [TaxId: 274] [102586] (1) picpic
      2. Thermotoga maritima [TaxId: 2336] [69559] (2) picpic
      3. Bacillus subtilis [TaxId: 1423] [82478] (1) picpic
      4. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117680] (5) picpic
        SQ Q9ZUB3
      5. Caenorhabditis elegans [TaxId: 6239] [142589] (2) picpic
        SQ Q9U2F0 3-314
      6. Human (Homo sapiens) [TaxId: 9606] [142590] (8) picpic
        SQ P19623 15-300
    2. Putative spermidine synthetase PF0127 (SpeE) [82479]
      1. Archaeon Pyrococcus furiosus [TaxId: 2261] [82480] (1) picpic
  37. Mycolic acid cyclopropane synthase [69560] (6)
    1. CmaA1 [69561]
      1. Mycobacterium tuberculosis [TaxId: 1773] [69562] (3) picpic
    2. CmaA2 [116723]
      1. Mycobacterium tuberculosis [TaxId: 1773] [116724] (1) picpic
    3. PccA [75269]
      1. Mycobacterium tuberculosis [TaxId: 1773] [75270] (1) picpic
    4. Methoxy mycolic acid synthase 2, Mma2 [117681]
      1. Mycobacterium tuberculosis [TaxId: 1773] [117682] (1) picpic
        SQ P72026 33-317
    5. Methoxy mycolic acid synthase 4, Mma4 [142591]
      1. Mycobacterium tuberculosis [TaxId: 1773] [142592] (2) picpic
        SQ Q79FX8 22-301
    6. Putative sarcosine dimethylglycine methyltransferase [159680]
      sequence similarity to other families with less structural similarity
      1. Red algae (Galdieria sulphuraria) [TaxId: 130081] [159681] (1) picpic
  38. Ta1320-like [89751] (2)
    1. Hypothetical protein Ta1320 [89752]
      1. Archaeon Thermoplasma acidophilum [TaxId: 2303] [89753] (1) picpic
    2. Hypothetical protein PH1948 [142593]
      1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [142594] (4) picpic
        SQ O59611 4-204
  39. UbiE/COQ5-like [110671] (5)
    Pfam 01209
    1. Hypothetical protein BH2331 [110672]
      1. Bacillus halodurans [TaxId: 86665] [110673] (1) picpic
        SQ Q9KAF6
    2. Possible histamine N-methyltransferase TM1293 [110674]
      1. Thermotoga maritima [TaxId: 2336] [110675] (1) picpic
        SQ Q9X119
    3. Hypothetical protein YcgJ [117683]
      1. Bacillus subtilis [TaxId: 1423] [117684] (3) picpic
        SQ O31474
    4. Hypothetical methyltransferase TM1389 [142595]
      1. Thermotoga maritima [TaxId: 2336] [142596] (2) picpic
        SQ Q9X1A9 1-246
    5. Hypothetical protein ECA1738 [159682]
      1. Erwinia carotovora [TaxId: 554] [159683] (6) picpic
        SQ Q6D6E7 21-249
  40. AD-003 protein-like [117685] (2)
    Pfam 05891; DUF858
    1. Hypothetical protein Lmaj004091aaa (LmjF30.0810) [117686]
      1. Leishmania major [TaxId: 5664] [117687] (1) picpic
        SQ Q4Q7M2
    2. Adrenal gland protein AD-003 (C9orf32) [142597]
      1. Human (Homo sapiens) [TaxId: 9606] [142598] (2) picpic
        SQ Q9BV86 1-222
  41. CAC2371-like [117688] (3)
    similar overall fold to the Glycine N-methyltransferase (scop_fa 53348) and mRNA cap (Guanine N-7) methyltransferase (scop_fa 102560) families
    1. Putative methyltransferase CAC2371 [117689]
      1. Clostridium acetobutylicum [TaxId: 1488] [117690] (1) picpic
        SQ Q97GJ5
    2. Hypothetical protein PH0226 [142599]
      1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [142600] (2) picpic
        SQ O57965 2-227
    3. Hypothetical methyltransferase PH1305 [142601]
      the beta-sheet insertion makes trimerization subdomain
      1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [142602] (3) picpic
        SQ O59000 1-251
  42. TehB-like [142603] (1)
    Pfam 03848; overall structural similarity to Thiopurine S-methyltransferase (Pfam 05724)
    1. Putative methyltransferase TehB [142604]
      Tellurite resistance protein
      1. Salmonella typhimurium [TaxId: 90371] [142605] (2) picpic
        SQ Q8ZPC3 1-198
        sequence similarity to Hypothetical methyltransferase PH1305 of the CAC2371-like family (scop_fa 117688)
  43. N-6 DNA Methylase-like [142606] (3)
    Pfam 02384; contains C-terminal extension to the canonical fold and extra N-terminal all-alpha domain similar to the insert domain of the DAM family (scop_fa 88788)
    1. Hypothetical protein Lmo1582 [142607]
      1. Listeria monocytogenes [TaxId: 1639] [142608] (1) picpic
        SQ Q8Y6U9 2-329
    2. M.EcoKI [142609]
      contains extra C-terminal structured region
      1. Escherichia coli [TaxId: 562] [142610] (2) picpic
        SQ P08957 4-527
    3. Type I restriction enzyme StySJI M protein [159684]
      1. Bacteroides thetaiotaomicron [TaxId: 818] [159685] (2) picpic
        SQ Q89Z59 9-433
  44. YhhF-like [142611] (5)
    Pfam 03602
    1. Putative methylase EF2452 [142612]
      1. Enterococcus faecalis [TaxId: 1351] [142613] (2) picpic
        SQ Q831P8 1-182
    2. Methyltransferase TTHA0928 [142614]
      1. Thermus thermophilus [TaxId: 274] [142615] (1) picpic
        SQ Q5SJT0 15-185
    3. Putative methylase HI0767 [142616]
      YhhF homologue
      1. Haemophilus influenzae [TaxId: 727] [142617] (1) picpic
        SQ P44869 11-193
    4. Putative methyltransferase SPy1538 [142618]
      1. Streptococcus pyogenes [TaxId: 1314] [142619] (2) picpic
        SQ Q99YU1 28-179
    5. Methylase YhhF [142620]
      1. Escherichia coli [TaxId: 562] [142621] (6) picpic
        SQ P0ADX9 10-192
  45. Met-10+ protein-like [142622] (1)
    Pfam 02475; contains extra N-terminal alpha+beta domain: beta(2)-alpha-beta(2); mixed beta-sheet; order: 1234; cf scop_fold 102740
    1. Hypothetical protein PH0793 [142623]
      1. Pyrococcus horikoshii [TaxId: 53953] [142624] (1) picpic
        SQ O58523 19-278
  46. Nsp15 N-terminal domain-like [142625] (2)
    rudiment methyltransferase fold that probably has lost the enzymatic activity; contains extra N-terminal alpha+beta subdomain
    1. Nsp15 [142626]
      1. Murine hepatitis virus, MHV [TaxId: 11138] [142627] (2) picpic
        SQ P16342 6504-6697! SQ P16342 6697-6872
      2. SARS coronavirus [TaxId: 227859] [142628] (11) picpic
        SQ Q6VA80 6619-6774
  47. BC2162-like [142629] (1)
    contains extra helical regions inserted after strands 5 and 6 of the canonical fold
    1. Methyltransferase BC2162 [142630]
      1. Bacillus cereus [TaxId: 1396] [142631] (2) picpic
        SQ Q81E32 13-293
  48. CmcI-like [142632] (1)
    Pfam 04989; may have evolved different enzymatic activity
    1. Cephalosporin hydroxylase CmcI [142633]
      1. Streptomyces clavuligerus [TaxId: 1901] [142634] (34) picpic
        SQ O85726 2-233
  49. hypothetical RNA methyltransferase [142635] (4)
    C-terminal part of Pfam 03602; similar to (Uracil-5-)-methyltransferase (Pfam 05958)
    1. Putative methyltransferase Atu0340 [142636]
      there is no associated PUA domain; rudiment extra N-terminal subdomain
      1. Agrobacterium tumefaciens [TaxId: 358] [142637] (3) picpic
        SQ Q8UIF7 1-309
    2. Hypothetical protein TTHA1280, middle and C-terminal domains [142638]
      1. Thermus thermophilus [TaxId: 274] [142639] (10) picpic
        SQ Q5SIT4 65-382
    3. Hypothetical protein SMu776, middle and C-terminal domains [142640]
      1. Streptococcus mutans [TaxId: 1309] [142641] (1) picpic
        SQ Q8DUW5 69-385
    4. Hypothetical protein PH1915, middle and C-terminal domains [142642]
      1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [142643] (2) picpic
        SQ O59578 73-396
  50. RPA4359-like [142644] (1)
    Pfam 02636; DUF185
    1. Hypothetical protein RPA4359 [142645]
      1. Rhodopseudomonas palustris [TaxId: 1076] [142646] (2) picpic
        SQ Q6N1P6 2-366
  51. TrmB-like [142647] (2)
    Pfam 02390
    1. tRNA (guanine-N(7)-)-methyltransferase TrmB [142648]
      1. Streptococcus pneumoniae [TaxId: 1313] [142649] (2) picpic
        SQ P67506 8-211
      2. Bacillus subtilis [TaxId: 1423] [142650] (2) picpic
        SQ O34522 10-213
  52. Methyltransferase 10 domain [142651] (1)
    Pfam 05971; DUF890
    1. Methyltransferase 10 domain containing protein METT10D [142652]
      1. Human (Homo sapiens) [TaxId: 9606] [142653] (3) picpic
        SQ Q86W50 42-291
  53. YhiQ-like [159686] (3)
    Pfam 04445; DUF548; contains extra N-terminal alpha+beta subdomain [beta-alpha-beta(4)]
    1. Hypothetical protein YhiQ [159687]
      1. Escherichia coli [TaxId: 562] [159688] (1) picpic
        SQ P68568 1-250
      2. Salmonella typhimurium [TaxId: 90371] [159689] (1) picpic
        SQ Q9X6G2 1-252
      3. Shigella flexneri [TaxId: 623] [159690] (1) picpic
        SQ Q7UAV7 1-250
  54. FkbM-like [159691] (1)
    contains extra N-terminal alpha/beta and all-alpha subdomains
    1. Methyltransferase FkbM [159692]
      1. Methylobacillus flagellatus [TaxId: 405] [159693] (1) picpic
        SQ Q1GXX6 14-408
  55. ML2640-like [159694] (1)
    Pfam 02409; O-methyltransferase N-terminus (DUF142); most similar structure to the Leucine carboxy methyltransferase Ppm1 family
    1. Putative methyltransferase ML2640 [159695]
      1. Mycobacterium leprae [TaxId: 1769] [159696] (4) picpic
        SQ Q9CCZ4 8-310
  56. TRM1-like [159697] (1)
    Pfam 02005; contains extra C-terminal alpha+beta subdomain
    1. N(2),N(2)-dimethylguanosine tRNA methyltransferase Trm1 [159698]
      1. Pyrococcus horikoshii [TaxId: 53953] [159699] (5) picpic
        SQ O59493 3-377
  57. LPG1296-like [159700] (1)
    Pfam 04378; DUF519
    1. Uncharacterized protein LPG1296 [159701]
      involved in catabolism of external DNA
      1. Legionella pneumophila [TaxId: 446] [159702] (1) picpic
        SQ Q5ZVZ2 14-284
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk