Structural Classification of Proteins

Family: Retroviral integrase, catalytic domain

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: Ribonuclease H-like motif [53066]
3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
Superfamily: Ribonuclease H-like [53098]
consists of one domain of this fold
uperfamily
Family: Retroviral integrase, catalytic domain [53107]

Protein Domains:

Retroviral integrase, catalytic domain [53108]
1. Rous sarcoma virus RSV [TaxId: 11886] [53109] (21)
  1. 1cxq
    complexed with epe, gol; mutant
    1. chain a [33621]
  2. 1czb
    complexed with epe; mutant
    1. chain a [33622]
  3. 1cz9
    complexed with cit, sul; mutant
    1. chain a [33623]
  4. 1cxu
    complexed with cit, gol; mutant
    1. chain a [33624]
  5. 1vsd
    complexed with epe, mg, ohe
    1. chain a [33625]
  6. 1asu
    complexed with epe; mutant
    1. chain a [33626]
  7. 1asw
    complexed with epe, ipa; mutant
    1. chain a [33627]
  8. 1a5x
    complexed with y3
    1. chain a [33630]
  9. 1a5v
    complexed with mn, y3
    1. chain a [33629]
  10. 1vsf
    complexed with epe, mn
    1. chain a [33628]
  11. 1a5w
    complexed with y3
    1. chain a [33632]
  12. 1vse
    complexed with epe
    1. chain a [33631]
  13. 1vsh
    complexed with epe, ocy, zn
    1. chain a [33633]
  14. 1vsm
    1. chain a [33635]
  15. 1asv
    complexed with ohe; mutant
    1. chain a [33634]
  16. 1vsj
    complexed with cd, epe, ocy
    1. chain a [33636]
  17. 1vsi
    complexed with ca, epe, ocy
    1. chain a [33638]
  18. 1vsl
    complexed with zn2; mutant
    1. chain a [33637]
  19. 1vsk
    mutant
    1. chain a [33639]
  20. 1c0m
    mutant
    1. region a:49-216 [33640]
    2. region b:54-216 [33641]
    3. region c:49-216 [33642]
    4. region d:54-216 [33643]
  21. 1c1a
    mutant
    1. region a:52-216 [33644]
    2. region b:55-216 [33645]
2. Human immunodeficiency virus type 1 [TaxId: 11676] [53110] (19)
  1. 1exq
    complexed with cd, cl, so4; mutant
    1. chain a [33646]
    2. chain b [33647]
  2. 1hyv
    complexed with caf, cl, so4, tta; mutant
    1. chain a [61424]
  3. 1b9d
    complexed with cac, so4; mutant
    1. chain a [33649]
  4. 1b9f
    complexed with cac, so4; mutant
    1. chain a [33648]
  5. 2b4j
    automatically matched to d1biza_
    complexed with gol, po4; mutant
    1. region a:57-208 [127833]
  6. 2b4j
    automatically matched to d1biza_
    complexed with gol, po4; mutant
    1. region b:57-208 [127834]
  7. 1b92
    complexed with cac, so4; mutant
    1. chain a [33654]
  8. 1bis
    mutant
    1. chain a [33650]
    2. chain b [33651]
  9. 1biz
    complexed with cac; mutant
    1. chain a [33652]
    2. chain b [33653]
  10. 1bl3
    complexed with mg; mutant
    1. chain a [33655]
    2. chain b [33656]
    3. chain c [33657]
  11. 1qs4
    1. chain a [33658]
    2. chain b [33659]
    3. chain c [33660]
  12. 1itg
    complexed with cac; mutant
    1. chain a [33661]
  13. 1biu
    complexed with mg; mutant
    1. chain a [33663]
    2. chain b [33664]
    3. chain c [33665]
  14. 1hyz
    complexed with caf, cl, so4, tto; mutant
    1. chain a [61426]
  15. 1k6y
    complexed with k, po4, zn; mutant
    1. region a:56-210 [68240]
    2. region b:56-212 [68242]
    3. region c:56-209 [68244]
    4. region d:56-211 [68246]
  16. 1bhl
    complexed with cas; mutant
    1. chain a [33662]
  17. 1bi4
    mutant
    1. chain a [33666]
    2. chain b [33667]
    3. chain c [33668]
  18. 1ex4
    complexed with cps; mutant
    1. region a:56-222 [33670]
    2. region b:55-222 [33671]
  19. 2itg
    mutant
    1. chain a [33669]
3. Simian immunodeficiency virus [TaxId: 11723] [53111] (1)
  1. 1c6v
    mutant
    1. chain a [33672]
    2. chain b [33673]
    3. chain c [33674]
    4. chain d [33675]