Structural Classification of Proteins
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Protein: Chloride intracellular channel 1 (clic1) from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Thioredoxin fold [52832]
    core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
  4. Superfamily: Thioredoxin-like [52833]
    link to SUPERFAMILY database - Superfamily
  5. Family: Glutathione S-transferase (GST), N-terminal domain [52862]
  6. Protein: Chloride intracellular channel 1 (clic1) [69514]
    similar to class theta enzymes; the N-domain undergoes a redox-controlled structural transition
  7. Species: Human (Homo sapiens) [TaxId: 9606] [69515]

PDB Entry Domains:

  1. 1k0m picpicxref
    mutant
    1. region a:6-91 [67950] picpiclink
    2. region b:6-91 [67952] picpiclink
  2. 1rk4 picpicxref
    oxidized form; adopts different all-alpha dimeric fold
    1. region a:22-91 [97593] picpiclink
    2. region b:22-91 [97595] picpiclink
  3. 1k0o picpicxref
    mutant
    1. region a:6-91 [67958] picpiclink
    2. region b:6-89 [67960] picpiclink
  4. 1k0n picpicxref
    complexed with gtt; mutant
    1. region a:6-91 [67954] picpiclink
    2. region b:6-91 [67956] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk