Structural Classification of Proteins
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Family: Glutathione peroxidase-like

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Thioredoxin fold [52832]
    core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
  4. Superfamily: Thioredoxin-like [52833]
    link to SUPERFAMILY database - Superfamily
  5. Family: Glutathione peroxidase-like [52901]

Protein Domains:

  1. Glutathione peroxidase [52902]
    contains many insertions in the common fold
    1. Cow (Bos taurus) [TaxId: 9913] [52903] (1) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [142365] (2) picpic
      SQ P07203 12-195
  2. Tryparedoxin I [52904]
    1. Crithidia fasciculata [TaxId: 5656] [52905] (8) picpic
    2. Trypanosoma brucei brucei [TaxId: 5702] [89707] (1) picpic
  3. Tryparedoxin II [64062]
    1. Crithidia fasciculata [TaxId: 5656] [64063] (6) picpic
  4. Tryparedoxin peroxidase (thioredoxin peroxidase homologue) [64064]
    1. Crithidia fasciculata [TaxId: 5656] [64065] (1) picpic
    2. Trypanosoma cruzi [TaxId: 5693] [117598] (1) picpic
      SQ O96763
  5. Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin) [52906]
    1. Norway rat (Rattus norvegicus) [TaxId: 10116] [52907] (1) picpic
      heme-binding protein 23, HBP23
    2. Human (Homo sapiens) [TaxId: 9606] [52908] (1) picpic
    3. Plasmodium yoelii [TaxId: 5861] [142366] (1) picpic
      SQ Q86SB2 8-177
  6. Peroxiredoxin 5 [64066]
    1. Human (Homo sapiens) [TaxId: 9606] [64067] (10) picpic
      SQ P30044
  7. 1-Cys peroxiredoxin [52909]
    1. Human (Homo sapiens) [TaxId: 9606] [52910] (1) picpic
    2. Plasmodium yoelii yoelii [TaxId: 73239] [117599] (1) picpic
      SQ Q7RGR1
    3. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [142367] (2) picpic
      SQ Q5MYR6 60-238
  8. Alkyl hydroperoxide reductase AhpC [69516]
    1. Salmonella typhimurium [TaxId: 90371] [69517] (26) picpic
    2. Mycobacterium tuberculosis [TaxId: 1773] [142368] (3) picpic
      SQ Q7BHK8 2-170
    3. Amphibacillus xylanus [TaxId: 1449] [142369] (10) picpic
      SQ O87200 2-167
  9. N-terminal, Prx domain of Hybrid-Prx5 [89708]
    1. Haemophilus influenzae [TaxId: 727] [89709] (1) picpic
      HI0572
  10. Probable thiol peroxidase PsaD [89710]
    1. Streptococcus pneumoniae [TaxId: 1313] [89711] (1) picpic
  11. Thiol peroxidase Tpx [102452]
    1. Escherichia coli [TaxId: 562] [102453] (1) picpic
    2. Haemophilus influenzae [TaxId: 727] [102454] (1) picpic
      HI0751
    3. Mycobacterium tuberculosis [TaxId: 1773] [117600] (3) picpic
      SQ P66952
  12. Membrane-anchored thioredoxin-like protein TlpA, soluble domain [64068]
    1. Bradyrhizobium japonicum [TaxId: 375] [64069] (1) picpic
  13. Thioredoxin-like protein CcmG (CycY, DsbE) [75237]
    1. Bradyrhizobium japonicum [TaxId: 375] [75238] (1) picpic
    2. Escherichia coli [TaxId: 562] [142370] (1) picpic
      SQ P0AA86 49-184
  14. Thiol-disulfide oxidoreductase ResA [102455]
    1. Bacillus subtilis [TaxId: 1423] [102456] (6) picpic
  15. Soluble secreted antigen MPT53 [102457]
    1. Mycobacterium tuberculosis [TaxId: 1773] [102458] (1) picpic
  16. Thioredoxin-like protein Sco1 (YpmQ), soluble domain [102459]
    1. Bacillus subtilis [TaxId: 1423] [102460] (3) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [142371] (5) picpic
      SQ O75880 138-297
    3. Baker's yeast(Saccharomyces cerevisiae) [TaxId: 4932] [142372] (8) picpic
      SQ P23833 111-262
  17. Phenol hydroxylase, C-terminal domain [52911]
    1. Soil-living yeast (Trichosporon cutaneum) [TaxId: 5554] [52912] (2) picpic
  18. Peroxiredoxin [117601]
    1. Aeropyrum pernix [TaxId: 56636] [117602] (50) picpic
      SQ Q9Y9L0 # APE2278
  19. thiol:disulfide oxidoreductase YkuV [142373]
    1. Bacillus subtilis [TaxId: 1423] [142374] (2) picpic
      SQ O31699 1-143
  20. Lipoprotein DsbF [142375]
    1. Mycobacterium tuberculosis [TaxId: 1773] [142376] (1) picpic
      SQ O53924 47-180
  21. Bacterioferritin comigratory protein [142377]
    1. Archaeon Aeropyrum pernix [TaxId: 56636] [142378] (12) picpic
      SQ Q9YA14 4-163
  22. Plant peroxiredoxin [142379]
    1. Western balsam poplar(Populus trichocarpa) [TaxId: 3694] [142380] (4) picpic
      SQ Q8S3L0 1-162
  23. Putative peroxiredoxin Rv2238c/MT2298 [142381]
    1. Mycobacterium tuberculosis [TaxId: 1773] [142382] (6) picpic
      SQ P65688 1-153
  24. Thioredoxin reductase TsaA [142383]
    1. Helicobacter pylori [TaxId: 210] [142384] (10) picpic
      SQ P56876 1-170
  25. Peptide methionine sulfoxide reductase MsrA/MsrB, N-terminal domain [142385]
    1. Neisseria meningitidis serogroup A [TaxId: 65699] [142386] (3) picpic
      SQ Q9JWM8 33-175
  26. Peroxiredoxin dot5 [142387]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [142388] (1) picpic
      SQ P40553 59-214
  27. Probable thiol-disulfide isomerase/thioredoxin TTHA0593 [142389]
    1. Thermus thermophilus [TaxId: 274] [142390] (2) picpic
      SQ Q5SKQ0 2-188
  28. Peroxiredoxin-3 (AOP-1, SP-22) [142391]
    1. Cow (Bos taurus) [TaxId: 9913] [142392] (12) picpic
      SQ P35705 63-220
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk