Structural Classification of Proteins
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Protein: Tyrosine phosphatase from Human (Homo sapiens), shp-2 [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: (Phosphotyrosine protein) phosphatases II [52798]
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. Superfamily: (Phosphotyrosine protein) phosphatases II [52799]
    share with the family I the common active site structure with a circularly permuted topology
    link to SUPERFAMILY database - Superfamily
  5. Family: Higher-molecular-weight phosphotyrosine protein phosphatases [52805]
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. Protein: Tyrosine phosphatase [52806]
  7. Species: Human (Homo sapiens), shp-2 [TaxId: 9606] [52810]

PDB Entry Domains:

  1. 2shp picpicxref
    contains tandem repeat of two SH2 domains in the N-terminal region
    complexed with cat; mutant
    1. region a:219-525 [32683] picpiclink
    2. region b:219-525 [32684] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk